Neo-adjuvant Gemcitabine, Epirubicin, ABI-007 (GEA) in Locally Advanced or Inflammatory Breast Cancer

Inclusion Criteria:

To be included in this study, you must meet the following criteria:

Locally advanced/inflammatory adenocarcinoma of the breast
18 years of age or older
Normal heart function
Able to perform activities of daily living with minimal assistance
No prior chemotherapy for breast cancer
Adequate bone marrow, liver and kidney function
No evidence or history of significant cardiovascular abnormalities
Sentinel node or axillary dissection
Sign an informed consent form

Exclusion Criteria:

You cannot participate in this study if any of the following apply to you:

Pregnant or breast feeding
History of heart disease with congestive heart failure
Heart attack within the previous 6 months
Prior chemotherapy or hormone therapy for breast cancer
History of active uncontrolled infection

Please note: There are additional inclusion/exclusion criteria. The study center will determine if you meet all of the criteria. If you do not qualify for the trial, study personnel will explain the reasons. If you do qualify, study personnel will explain the trial in detail and answer any questions you may have.