Breast Cancer Clinical Trial
Optimizing Treatment of Stage IV Breast Cancer Through Real-Time Disease Monitoring
Summary
This study evaluates if blood tests can detect changes in disease status during treatment for stage IV breast cancer. Information from this study may help researchers learn more about metastatic breast cancer and how to optimize treatment.
Full Description
PRIMARY OBJECTIVES:
I. To identify subtype-specific signatures for breast cancer using genomic positioning of plasma deoxyribonucleic acid (DNA) fragments.
II. To validate changes in circulating tumor-derived DNA (ctDNA) levels as a biomarker for treatment monitoring in patients with metastatic breast cancer.
OUTLINE:
Patients undergo collection of blood samples at baseline, 2 weeks after the start of treatment, and at the beginning of each new treatment cycle.
Eligibility Criteria
Inclusion Criteria:
All women > 18 years of age
Stage IV breast cancer undergoing cancer treatment
Exclusion Criteria:
Stage I-III breast cancer
Unwilling or unable to give consent
Patients with a prior or concurrent malignancy, excluding non-melanoma skin cancers and non-invasive cancers whose natural history or treatment does not have the potential to interfere with the assessment of the investigational marker
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There is 1 Location for this study
Scottsdale Arizona, 85259, United States More Info
Principal Investigator
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