Breast Cancer Clinical Trial

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Prevention of Heart Failure Induced by Doxorubicin With Early Administration of Dexrazoxane

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Summary

The purpose of this research study is to determine whether early administration of Dexrazoxane prevents Doxorubicin induced cardiotoxicity.

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Full Description

This is a study on volunteers to determine effective dose of dexrazoxane in degrading Topoisomerase 2 b in human blood samples. Each participant will receive one dose of dexrazoxane. Blood samples will be collected to determine the time course and degradation of Topoisomerase 2b and Topoisomerase 2a

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Eligibility Criteria

Inclusion Criteria:

Women,
Age 18-65,
Not pregnant, Not currently breast feeding
No current illness,

Exclusion Criteria:

Pregnancy, currently breast feeding
Current illness,
History of cardiac, or renal disease

Study is for people with:

Breast Cancer

Phase:

Phase 1

Estimated Enrollment:

25

Study ID:

NCT03930680

Recruitment Status:

Recruiting

Sponsor:

University of Arkansas

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There is 1 Location for this study

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University of Arkansas for Medical Sciences
Little Rock Arkansas, 72205, United States More Info
Hui-Ming Chang, MD, MPH
Contact
501-686-7575
[email protected]

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Phase:

Phase 1

Estimated Enrollment:

25

Study ID:

NCT03930680

Recruitment Status:

Recruiting

Sponsor:


University of Arkansas

How clear is this clinincal trial information?

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