Breast Cancer Clinical Trial

Roll Over StudY for Patients Who Have Completed a Previous Oncology Study With Olaparib

Summary

The rationale of the ROSY-O study is to continue to provide study treatment for patients who have participated in a parent study with olaparib and who are continuing to derive clinical benefit from treatment at the end of such studies, as judged by the Investigator.

View Full Description

Full Description

ROSY-O is an open label, non-randomised, multicentre,international trial for patients who have completed a parent study using olaparib and who are deriving clinical benefit from continued treatment as judged by the Investigator. Patients will be rolled-over from the parent study and will continue the study indefinitely, until they meet one of the treatment discontinuation criteria

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Provision of signed and dated, written ICF.
Patient is currently deriving clinical benefit, as judged by the Investigator, from continued treatment in an AZ parent study using an AstraZeneca (AZ) compound that has met its endpoints or has otherwise stopped.
Patient participating in a prior oncology study with an AZ compound in which they received olaparib and are continuing to receive clinical benefit from treatment; the prior study can be an open-label or blinded study, with unblinding at study close.

Exclusion Criteria:

Ongoing, unresolved, Grade 3 or above toxicity requiring interruption of treatment at the time of the termination of the parent study.
Currently receiving treatment with any prohibited medication(s).
Concurrently enrolled in any other type of medical research judged not to be scientifically or medically compatible with this study.
Permanent discontinuation from the parent study due to toxicity or disease progression.
Local access to commercially-available drug at no cost to the patient is permitted by local regulation.

Study is for people with:

Breast Cancer

Phase:

Phase 3

Estimated Enrollment:

292

Study ID:

NCT04421963

Recruitment Status:

Enrolling by invitation

Sponsor:

AstraZeneca

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There are 110 Locations for this study

See Locations Near You

Research Site
West Hollywood California, 90048, United States
Research Site
Boca Raton Florida, 33486, United States
Research Site
Towson Maryland, 21204, United States
Research Site
Detroit Michigan, 48201, United States
Research Site
Minneapolis Minnesota, 55407, United States
Research Site
Basking Ridge New Jersey, 07920, United States
Research Site
Hackensack New Jersey, 07601, United States
Research Site
Bronx New York, 10461, United States
Research Site
New York New York, 10032, United States
Research Site
Philadelphia Pennsylvania, 19104, United States
Research Site
Pittsburgh Pennsylvania, 15224, United States
Research Site
Willow Grove Pennsylvania, 19090, United States
Research Site
Providence Rhode Island, 02905, United States
Research Site
Germantown Tennessee, 38138, United States
Research Site
Houston Texas, 77030, United States
Research Site
Leuven , 3000, Belgium
Research Site
Namur , 5000, Belgium
Research Site
Rio de Janeiro , 22793, Brazil
Research Site
Plovdiv , 4000, Bulgaria
Research Site
Plovdiv , 4004, Bulgaria
Research Site
Halifax Nova Scotia, B3H 1, Canada
Research Site
Kingston Ontario, K7L 2, Canada
Research Site
Mississauga Ontario, L5M 2, Canada
Research Site
Ottawa Ontario, K1H 8, Canada
Research Site
Toronto Ontario, M4N 3, Canada
Research Site
Toronto Ontario, M5G 2, Canada
Research Site
Montreal Quebec, H1T 2, Canada
Research Site
Montreal Quebec, H2X 0, Canada
Research Site
Montreal Quebec, H3T 1, Canada
Research Site
Montreal Quebec, H4A-3, Canada
Research Site
Quebec City Quebec, G1S 4, Canada
Research Site
Changchun , 13002, China
Research Site
Hangzhou , 31002, China
Research Site
Shanghai , 20003, China
Research Site
Brno , 625 0, Czechia
Research Site
Brno , 656 5, Czechia
Research Site
Olomouc , 779 0, Czechia
Research Site
Ostrava Poruba , 708 5, Czechia
Research Site
Praha 2 , 128 0, Czechia
Research Site
Praha 5 , 150 0, Czechia
Research Site
Aalborg , 9000, Denmark
Research Site
Kuopio , 70210, Finland
Research Site
Lille Cedex , 59020, France
Research Site
Lyon , 69373, France
Research Site
Plerin , 22190, France
Research Site
Villejuif , 94800, France
Research Site
Dresden , 1307, Germany
Research Site
Budapest , 1032, Hungary
Research Site
Budapest , 1122, Hungary
Research Site
Haifa , 31096, Israel
Research Site
Jerusalem , 91031, Israel
Research Site
Jerusalem , 91120, Israel
Research Site
Petah Tikva , 49100, Israel
Research Site
Ramat Gan , 52656, Israel
Research Site
Tel Aviv , 64239, Israel
Research Site
Ancona , 60020, Italy
Research Site
Bologna , 40138, Italy
Research Site
Brescia , 25123, Italy
Research Site
Candiolo , 10060, Italy
Research Site
Catania , 95126, Italy
Research Site
Lecce , 73100, Italy
Research Site
Lecco , 23900, Italy
Research Site
Milano , 20132, Italy
Research Site
Milan , 20141, Italy
Research Site
Napoli , 80131, Italy
Research Site
Padova , 35128, Italy
Research Site
Roma , 00168, Italy
Research Site
Torino , 10128, Italy
Research Site
Verona , 37134, Italy
Research Site
Seoul , 01812, Korea, Republic of
Research Site
Seoul , 03080, Korea, Republic of
Research Site
Seoul , 03722, Korea, Republic of
Research Site
Seoul , 06273, Korea, Republic of
Research Site
Seoul , 06351, Korea, Republic of
Research Site
Seoul , 6351, Korea, Republic of
Research Site
Białystok , 15-02, Poland
Research Site
Grzepnica , 72-00, Poland
Research Site
Lublin , 20-09, Poland
Research Site
Olsztyn , 10-56, Poland
Research Site
Poznan , 61-86, Poland
Research Site
Poznań , 60-56, Poland
Research Site
Porto , 4200-, Portugal
Research Site
Sankt-Peterburg , 19775, Russian Federation
Research Site
Ljubljana , 1000, Slovenia
Research Site
Badalona , 08916, Spain
Research Site
Barcelona , 08035, Spain
Research Site
Barcelona , 8907, Spain
Research Site
Barcelona , ?0804, Spain
Research Site
Cordoba , 14004, Spain
Research Site
Granada , 18014, Spain
Research Site
Madrid , 28027, Spain
Research Site
Madrid , 28041, Spain
Research Site
Madrid , 28046, Spain
Research Site
Pamplona , 31008, Spain
Research Site
San Sebastian , 20014, Spain
Research Site
Valencia , 46026, Spain
Research Site
Vigo , 36312, Spain
Research Site
Zaragoza , 50009, Spain
Research Site
Lund , 22185, Sweden
Research Site
Taipei , 112, Taiwan
Research Site
Ankara , 06230, Turkey
Research Site
Istanbul , 34093, Turkey
Research Site
Sahinbey , 27310, Turkey
Research Site
Birmingham , B18 7, United Kingdom
Research Site
Edinburgh , EH4 2, United Kingdom
Research Site
Glasgow , G12 O, United Kingdom
Research Site
Hull , HU16 , United Kingdom
Research Site
London , SW3 6, United Kingdom
Research Site
Manchester , M20 4, United Kingdom
Research Site
Taunton , TA1 5, United Kingdom

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Phase:

Phase 3

Estimated Enrollment:

292

Study ID:

NCT04421963

Recruitment Status:

Enrolling by invitation

Sponsor:


AstraZeneca

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.

Please confirm you are a US based health care provider:

Yes, I am a health care Provider No, I am not a health care provider