Breast Cancer Clinical Trial

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Study of Dasatinib (BMS-354825) in Patients With Advanced Estrogen/Progesterone Receptor-positive (ER+/PR+) or Her2/Neu-positive (Her2/Neu+)Breast Cancer

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Summary

This study will determine whether the investigational drug dasatinib is effective in treatment of women with progressive advanced ER+/PR+ or Her2/neu+ breast cancer

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

females, 18 or older
recurrent, locally advanced, or metastatic breast cancer with expression of ER/PR receptor and/or overexpression of Her2/neu
paraffin-embedded tissue block must be available
measurable disease
prior chemotherapy with an anthracycline and/or a taxane (neoadjuvant, adjuvant, or metastatic setting)
0, 1 or 2 chemotherapies in the metastatic setting
adequate organ function

Exclusion Criteria:

Metastatic disease confined to bone only
Symptomatic central nervous system (CNS) metastasis
Concurrent medical condition which may increase the risk of toxicity
Unable to take oral medication

Study is for people with:

Breast Cancer

Phase:

Phase 2

Estimated Enrollment:

92

Study ID:

NCT00371345

Recruitment Status:

Completed

Sponsor:

Bristol-Myers Squibb

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There are 22 Locations for this study

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Ucsf-Comprehensive Cancer Center
San Francisco California, 94143, United States
Mayo Clinic Florida
Jacksonville Florida, 32224, United States
Dana-Farber Cancer Inst
Boston Massachusetts, 02115, United States
Montefiore Medical Center
Bronx New York, 10461, United States
University Of North Carolina At Chapel Hill
Chapel Hill North Carolina, 27599, United States
Fox Chase Cancer Center
Philadelphia Pennsylvania, 19111, United States
University Of Texas Md Anderson Cancer Ctr
Houston Texas, 77030, United States
Local Institution
Haedo Buenos Aires, 1684, Argentina
Local Institution
Buenos Aires , 1019, Argentina
Local Institution
Buenos Aires , 1185, Argentina
Local Institution
Bruxelles , 1000, Belgium
Local Institution
Bruxelles , 1200, Belgium
Local Institution
Dijon Cedex , 21079, France
Local Institution
Paris , 75231, France
Local Institution
Saint Herblain Cedex , 44805, France
Local Institution
Toulouse Cedex 3 , 31052, France
Local Institution
Modena , 41100, Italy
Local Institution
Arequipa , , Peru
Local Institution
Lima , 34, Peru
Local Institution
Lima , LIMA , Peru
Local Institution
Barcelona , 08035, Spain
Local Institution
Lleida , 25198, Spain
Local Institution
Madrid , 28041, Spain
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How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Phase:

Phase 2

Estimated Enrollment:

92

Study ID:

NCT00371345

Recruitment Status:

Completed

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

Clinical Trial Resources

SurvivorNet’s Guide To Clinical Trials: What Are They And Are They Right for You?
Clinical Trials for Breast Cancer
Have You Been Diagnosed With Late-Stage Breast Cancer? Know That You Have Treatment Options.
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