Breast Cancer Clinical Trial

Study of NGM707 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

Summary

Study of NGM707 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor Malignancies

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Histologically or cytologically documented locally advanced or metastatic solid tumor malignancy.
Progressed or was intolerant to all available therapies known to confer clinical benefit appropriate for their tumor type, and for which the patient was eligible and willing to receive, or refused SOC treatments that are perceived to have marginal clinical benefit.
Adequate bone marrow, kidney and liver function.
Performance status of 0 or 1.
Resolved acute effects of any prior therapy to baseline severity or CTCAE Grade 1 except for AEs not constituting a safety risk by Investigator judgement.

Exclusion Criteria:

Prior treatment targeting ILT2 and/or ILT4 or targeting HLA-G.

Study is for people with:

Breast Cancer

Phase:

Phase 1

Estimated Enrollment:

179

Study ID:

NCT04913337

Recruitment Status:

Active, not recruiting

Sponsor:

NGM Biopharmaceuticals, Inc

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There are 27 Locations for this study

See Locations Near You

NGM Clinical Study Site
Los Angeles California, 90033, United States
NGM Clinical Study Site
Newport Beach California, 92663, United States
NGM Clinical Study Site
Santa Monica California, 90404, United States
NGM Clinical Study Site
Santa Rosa California, 94505, United States
NGM Clinical Study Site
Lone Tree Colorado, 80124, United States
NGM Clinical Study Site
Washington District of Columbia, 20007, United States
NGM Clinical Study Site
Sarasota Florida, 34232, United States
NGM Clinical Study Site
Baltimore Maryland, 21201, United States
NGM Clinical Study Site
Boston Massachusetts, 02215, United States
NGM Clinical Study Site
Grand Rapids Michigan, 49546, United States
NGM Clinical Study Site
Omaha Nebraska, 68130, United States
NGM Clinical Study Site
Albany New York, 12206, United States
NGM Clinical Study Site
Greenville South Carolina, 29605, United States
NGM Clinical Study Site
Dallas Texas, 75246, United States
NGM Clinical Study Site
Dallas Texas, 78701, United States
NGM Clinical Study Site
Houston Texas, 77030, United States
NGM Clinical Study Site
San Antonio Texas, 78229, United States
NGM Clinical Study Site
San Antonio Texas, 78240, United States
NGM Clinical Study Site
Blacksburg Virginia, 24060, United States
NGM Clinical Study Site
Vancouver Washington, 98684, United States
NGM Clinical Study Site
Seoul , 03080, Korea, Republic of
NGM Clinical Study Site
Seoul , 05505, Korea, Republic of
NGM Clinical Study Site
Seoul , 06351, Korea, Republic of
NGM Clinical Study Site
New Taipei City , 235, Taiwan
NGM Clinical Study Site
Taichung , 40432, Taiwan
NGM Clinical Study Site
Tainan , 704, Taiwan
NGM Clinical Study Site
Taipei , 10022, Taiwan

How clear is this clinincal trial information?

Study is for people with:

Breast Cancer

Phase:

Phase 1

Estimated Enrollment:

179

Study ID:

NCT04913337

Recruitment Status:

Active, not recruiting

Sponsor:


NGM Biopharmaceuticals, Inc

How clear is this clinincal trial information?

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