Transgender and Gender-Diverse Breast Cancer Screening Pilot

Inclusion Criteria for Transfeminine/Nonbinary/Gender-Diverse Persons:

Assigned male or intersex at birth and do not identify as cisgender

Age:

40-75 years
35-39 years with a family history of breast cancer, defined as ≥1 1st or 2nd degree relative(s) with a breast cancer diagnosis
30-34 with a 1st degree relative with a breast cancer diagnosis age ≤45
A history of gender-affirming hormone therapy ≥9 months.
Ability to speak, read, and write in English.
Ability to understand a written informed consent document, and the willingness to sign it.

Inclusion Criteria for Transmasculine/Nonbinary/Gender-Diverse Persons:

Assigned female or intersex at birth and do not identify as cisgender

Age:

40-75 years
35-39 years with a family history of breast cancer, defined as ≥1 1st or 2nd degree relative(s) with a breast cancer diagnosis
30-34 years with a 1st degree relative with a breast cancer diagnosis age ≤45
Any history of gender-affirming hormone therapy, regardless of duration.
Has not undergone a complete mastectomy for oncologic or risk-reducing reasons. (Note: those who have undergone top surgery are eligible, assuming they meet this criterion).
Ability to speak, read, and write in English.
Ability to understand a written informed consent document, and the willingness to sign it.

Inclusion Criteria for Breast Radiology Faculty:

Board-certified radiologist that specializes in breast imaging and are an actively employed faculty member at Froedtert & the Medical College of Wisconsin (main campus location).
Part of the breast radiology faculty who read both ABUS and MMG of the TGD study participants.
Ability to speak, read, and write in English.
Ability to understand a written informed consent document, and the willingness to sign it.

Inclusion Criteria for Breast Radiology Staff:

Must be either a technician, nurse, or clerical staff that works with the breast radiology team at Froedtert & the Medical College of Wisconsin (main campus location).
Ability to understand a written informed consent document, and the willingness to sign it.
Ability to speak, read, and write in English.

Exclusion Criteria for Transfeminine/Nonbinary/Gender-Diverse Persons

Has a history of breast cancer.
Has a known pathogenic gene mutation that increases the risk of breast cancer development (e.g., BRCA1/2).
Has not been on GAHT for ≥ 9 months.

Exclusion Criteria for Transmasculine/Nonbinary/Gender-Diverse Persons

Has undergone or planned to undergo a complete mastectomy.
Has a history of breast cancer.
Has a known pathogenic gene mutation that increases the risk of breast cancer development (e.g., BRCA1/2).

Exclusion Criteria for Breast Radiology Faculty

Not a board-certified radiologist.
Does not specialize in breast imaging.
Does not read ABUS and MMG and/or has not read imaging for study participants.

Exclusion for Breast Radiology Staff

1. Does not work with the breast radiology team.