Esophageal Cancer Clinical Trial

An Investigational Immuno-therapy Study of Nivolumab or Placebo in Participants With Resected Esophageal or Gastroesophageal Junction Cancer

Summary

The primary purpose of this study is to determine whether immunotherapy-drugs-are-boosting-survival/" >Nivolumab will improve disease-free survival compared with placebo.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Diagnosed with Stage II/III carcinoma of the esophagus or gastroesophageal junction
Completed pre-operative chemo radiotherapy followed by surgery
Diagnosed with residual pathologic disease after being surgically rendered free of disease with negative margins following complete resection

Exclusion Criteria:

Diagnosed with cervical esophageal carcinoma
Diagnosed with Stage IV resectable disease
Did not receive concurrent chemoradiotherapy prior to surgery
Participants who have received a live/attenuated vaccine within 30 days of the first treatment

Other protocol defined Inclusion/exclusion criteria could apply

Study is for people with:

Esophageal Cancer

Phase:

Phase 3

Estimated Enrollment:

794

Study ID:

NCT02743494

Recruitment Status:

Active, not recruiting

Sponsor:

Bristol-Myers Squibb

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There are 192 Locations for this study

See Locations Near You

Local Institution - 0250
Tucson Arizona, 85711, United States
Local Institution - 0026
Los Angeles California, 90033, United States
Pacific Hematology Oncology Associates
San Francisco California, 94115, United States
Local Institution - 0068
San Francisco California, 94158, United States
Local Institution - 0151
Aurora Colorado, 80045, United States
Local Institution - 0247
Denver Colorado, 80218, United States
Local Institution - 0054
Washington District of Columbia, 20007, United States
Local Institution - 0113
Fort Myers Florida, 33901, United States
Local Institution - 0131
Jacksonville Florida, 32256, United States
Local Institution - 0226
Miami Florida, 33136, United States
Local Institution - 0022
Pensacola Florida, 32504, United States
Local Institution - 0114
Saint Petersburg Florida, 33705, United States
Local Institution - 0153
Chicago Illinois, 60637, United States
Local Institution - 0025
Baltimore Maryland, 21202, United States
Local Institution - 0055
Boston Massachusetts, 02215, United States
Local Institution - 0170
Boston Massachusetts, 02215, United States
Local Institution - 0171
Boston Massachusetts, 02215, United States
Local Institution - 0217
Boston Massachusetts, 02215, United States
Local Institution - 0027
Saint Louis Missouri, 63110, United States
Local Institution - 0058
Hackensack New Jersey, 07601, United States
Local Institution - 0066
Neptune New Jersey, 07753, United States
Local Institution - 0205
Bronx New York, 10461, United States
Local Institution - 0032
New York New York, 10016, United States
Local Institution - 0033
Charlotte North Carolina, 28262, United States
Local Institution - 0024
Durham North Carolina, 27710, United States
Local Institution - 0056
Cleveland Ohio, 44106, United States
Local Institution - 0165
Portland Oregon, 97239, United States
Local Institution - 0101
Allentown Pennsylvania, 18103, United States
Local Institution - 0048
Philadelphia Pennsylvania, 19111, United States
Local Institution - 0116
Pittsburgh Pennsylvania, 15224, United States
Local Institution - 0111
Nashville Tennessee, 37203, United States
Local Institution - 0130
Nashville Tennessee, 37232, United States
Local Institution - 0216
Dallas Texas, 75216, United States
Local Institution - 0248
Dallas Texas, 75246, United States
Local Institution - 0012
Houston Texas, 77030, United States
Local Institution - 0241
Seattle Washington, 98101, United States
Local Institution - 0067
Seattle Washington, 98109, United States
Local Institution - 0069
Madison Wisconsin, 53792, United States
Local Institution - 0050
Capital Federal Buenos Aires, 1264, Argentina
Local Institution - 0152
Capital Federal Buenos Aires, 1280, Argentina
Local Institution - 0164
Ciudad Autonoma Buenos Aires Distrito Federal, 1118, Argentina
Local Institution - 0207
Viedma RIO Negro, 8500, Argentina
Local Institution - 0208
Rosario Santa FE, 2000, Argentina
Local Institution - 0051
San Miguel De Tucuman Tucuman, 4000, Argentina
Local Institution - 0198
Buenos Aires , 1093 , Argentina
Local Institution - 0133
Caba , 1426, Argentina
Local Institution - 0112
Cordoba , X5006, Argentina
Local Institution - 0200
Blacktown New South Wales, 2148, Australia
Local Institution - 0098
Gosford New South Wales, 2250, Australia
Local Institution - 0074
St Leonards New South Wales, 2065, Australia
Local Institution - 0075
Tamworth New South Wales, 2340, Australia
Local Institution - 0237
Brisbane Queensland, 4102, Australia
Local Institution - 0123
Adelaide South Australia, 5000, Australia
Local Institution - 0072
Clayton Victoria, 3168, Australia
Local Institution - 0156
Perth Western Australia, 6150, Australia
Local Institution - 0099
Hobart , 7000, Australia
Local Institution - 0035
Bruxelles , 1200, Belgium
Local Institution - 0037
Edegem , 2650, Belgium
Local Institution - 0086
Gent , 9000, Belgium
Local Institution - 0034
Leuven , 3000, Belgium
Local Institution - 0036
Liege , 4000, Belgium
Local Institution - 0087
Namur , 5000, Belgium
Local Institution - 0095
Brasilia Distrito Federal, 70200, Brazil
Local Institution - 0096
Belo Horizonte Minas Gerais, 30130, Brazil
Local Institution - 0221
Curitiba Parana, 81520, Brazil
Local Institution - 0059
Ijui RIO Grande DO SUL, 98700, Brazil
Local Institution - 0060
Porto Alegre RIO Grande DO SUL, 90610, Brazil
Local Institution - 0223
Itacorubi, Florianopolis Santa Catarina, 88034, Brazil
Local Institution - 0061
Barretos Sao Paulo, 14780, Brazil
Local Institution - 0222
Sao Jose De Rio Preto Sao Paulo, 15091, Brazil
Local Institution - 0065
Rio de Janeiro , 22793, Brazil
Local Institution - 0064
Salvador , 0, Brazil
Local Institution - 0062
Sao Paulo , 01246, Brazil
Local Institution - 0063
Sao Paulo , 01308, Brazil
Local Institution - 0129
Edmonton Alberta, T6G 1, Canada
Local Institution - 0093
Vancouver British Columbia, V5Z 4, Canada
Local Institution - 0092
Halifax Nova Scotia, B3H 1, Canada
Local Institution - 0094
London Ontario, N6A 4, Canada
Local Institution - 0091
Ottawa Ontario, K1H 8, Canada
Local Institution - 0110
Toronto Ontario, M5G 2, Canada
Local Institution - 0134
Montreal Quebec, H4A 3, Canada
Local Institution - 0214
Trois-Rivieres Quebec, G8Z 3, Canada
Local Institution - 0109
Quebec , G1R 2, Canada
Local Institution - 0240
Beijing Beijing, 10014, China
Local Institution - 0234
Fuzhou Fujian, 35001, China
Local Institution - 0227
Shanghai Shanghai, 20003, China
Local Institution - 0239
Shanghai Shanghai, 20003, China
Local Institution - 0230
Hangzhou Zhejiang, 31000, China
Local Institution - 0238
Hangzhou Zhejiang, 31002, China
Local Institution - 0233
Linhai Zhejiang, 31700, China
Local Institution - 0232
Shanghai , 20003, China
Local Institution - 0228
Tianjin , 30006, China
Local Institution - 0031
Brno , 656 5, Czechia
Local Institution - 0029
Hradec Kralove , 500 0, Czechia
Local Institution - 0030
Olomouc , 779 0, Czechia
Local Institution - 0166
Aarhus N , 8200, Denmark
Local Institution - 0215
Avignon Cedes 9 , 84918, France
Local Institution - 0121
Dijon Cedex , 21079, France
Local Institution - 0117
Lille , 59037, France
Local Institution - 0119
Paris , 75012, France
Local Institution - 0120
Pessac , 33604, France
Local Institution - 0118
Pierre Benite Cedex , 69495, France
Local Institution - 0132
Rennes Cedex 9 , 35033, France
Local Institution - 0149
Rouen , 76000, France
Local Institution - 0148
Toulouse , 31403, France
Local Institution - 0006
Berlin , 13353, Germany
Local Institution - 0008
Essen , 45136, Germany
Local Institution - 0007
Hamburg , 20251, Germany
Local Institution - 0003
Koeln , 50937, Germany
Local Institution - 0001
Mainz , 55131, Germany
Local Institution - 0017
Marburg , 35043, Germany
Local Institution - 0005
Munich , 81675, Germany
Local Institution - 0011
Tuebingen , 72076, Germany
Local Institution - 0225
Hong Kong , 0, Hong Kong
Local Institution - 0053
Budapest , 1097, Hungary
Local Institution - 0224
Budapest , 1122, Hungary
Local Institution - 0052
Debrecen , 0, Hungary
Local Institution - 0057
Kaposvar , 7400, Hungary
Local Institution - 0039
Wilton Cork, 0, Ireland
Local Institution - 0040
Dublin , 9, Ireland
Local Institution - 0038
Galway , , Ireland
Local Institution - 0146
Haifa , 31096, Israel
Local Institution - 0144
Jerusalem , 91120, Israel
Local Institution - 0143
Petach Tikva , 49100, Israel
Local Institution - 0145
Ramat-gan , 52621, Israel
Local Institution - 0142
Tel Aviv , 64239, Israel
Local Institution - 0105
Bergamo , 24127, Italy
Local Institution - 0137
Milano , 20097, Italy
Local Institution - 0104
Milano , 20133, Italy
Local Institution - 0106
Reggio Emilia , 42100, Italy
Local Institution - 0107
Roma , 00168, Italy
Local Institution - 0173
Akita-Shi Akita, 01085, Japan
Local Institution - 0180
Chiba-shi Chiba, 26086, Japan
Local Institution - 0187
Fukuoka-shi Fukuoka, 81285, Japan
Local Institution - 0189
Gifu-shi Gifu, 50111, Japan
Local Institution - 0183
Hiroshima-Shi Hiroshima, 73485, Japan
Local Institution - 0192
Sapporo-shi Hokkaido, 00300, Japan
Local Institution - 0196
Sapporo-shi Hokkaido, 06086, Japan
Local Institution - 0191
Kagoshima-shi Kagoshima, 89085, Japan
Local Institution - 0184
Kumamoto-shi Kumamoto, 86085, Japan
Local Institution - 0188
Sendai-shi Miyagi, 98085, Japan
Local Institution - 0182
Osakasayama Osaka, 589-8, Japan
Local Institution - 0185
Suita-shi Osaka, 565-0, Japan
Local Institution - 0186
Kitaadachi-gun Saitama, 36208, Japan
Local Institution - 0172
Chuo-ku Tokyo, 10400, Japan
Local Institution - 0190
Koto-ku Tokyo, 13585, Japan
Local Institution - 0174
Minato-ku Tokyo, 10584, Japan
Local Institution - 0193
Shinjuku-ku Tokyo, 16000, Japan
Local Institution - 0204
Shinjuuku-ku Tokyo, 16085, Japan
Local Institution - 0194
Fukuoka , 81113, Japan
Local Institution - 0181
Kita-gun , 76107, Japan
Local Institution - 0175
Seoul , 05505, Korea, Republic of
Local Institution - 0176
Seoul , 120-7, Korea, Republic of
Local Institution - 0212
Tuxtla Gutierrez Chiapas, 29038, Mexico
Local Institution - 0085
Tlalpan Distrito Federal C.p., 14000, Mexico
Local Institution - 0127
Leon, Guanajato Guanajuato, 37000, Mexico
Local Institution - 0154
Aguascalientes , 20230, Mexico
Local Institution - 0168
Ciudad de Mexico , 06760, Mexico
Local Institution - 0084
Distrito Federal , 14080, Mexico
Local Institution - 0089
Amsterdam , 1066 , Netherlands
Local Institution - 0251
Groningen , 9700 , Netherlands
Local Institution - 0042
Groningen , 9713 , Netherlands
Local Institution - 0043
Maastrict , 6229 , Netherlands
Local Institution - 0195
Callao , 02, Peru
Local Institution - 0162
Lima , 34, Peru
Local Institution - 0141
Lima , LIMA , Peru
Local Institution - 0088
Lima , LIMA , Peru
Local Institution - 0255
Lublin Lubelskie, 20-08, Poland
Local Institution - 0253
Warszawa Mazowieckie, 02-78, Poland
Local Institution - 0083
Gliwice , 44-10, Poland
Local Institution - 0138
Krakow , 31-20, Poland
Local Institution - 0139
Lublin , 20-08, Poland
Local Institution - 0082
Poznan , 60-78, Poland
Local Institution - 0081
Warszawa , 02-78, Poland
Local Institution - 0097
San Juan , 00927, Puerto Rico
Local Institution - 0167
Baia Mare , 43029, Romania
Local Institution - 0163
Bucharest , 02232, Romania
Local Institution - 0197
Bucuresti , 02138, Romania
Local Institution - 0103
Cluj-napoca , 40035, Romania
Local Institution - 0028
Craiova , 20034, Romania
Local Institution - 0135
Floresti , 40728, Romania
Local Institution - 0213
Cheboksary , 42802, Russian Federation
Local Institution - 0125
Moscow , 11547, Russian Federation
Local Institution - 0209
Saint-Petersburg , 19702, Russian Federation
Local Institution - 0136
St. Petersburg , 19775, Russian Federation
Local Institution - 0218
Singapore , 11922, Singapore
Local Institution - 0219
Singapore , 16961, Singapore
Local Institution - 0078
Barcelona , 08035, Spain
Local Institution - 0079
Cordoba , 14004, Spain
Local Institution - 0080
Madrid , 28007, Spain
Local Institution - 0077
Madrid , 28050, Spain
Local Institution - 0018
Basel , 4031, Switzerland
Local Institution - 0047
St Gallen , 9007, Switzerland
Local Institution - 0177
Taichung , 40447, Taiwan
Local Institution - 0178
Tainan , 70403, Taiwan
Local Institution - 0179
Taipei , 100, Taiwan
Local Institution - 0160
Adana , 01250, Turkey
Local Institution - 0161
Erzurum , 25240, Turkey
Local Institution - 0157
Istanbul , 34300, Turkey
Local Institution - 0203
London Greater London, NW1 2, United Kingdom
Local Institution - 0045
London Greater London, SW3 6, United Kingdom
Local Institution - 0046
Southampton Hampshire, SO16 , United Kingdom
Local Institution - 0049
Withington Manchester, M20 4, United Kingdom
Local Institution - 0169
Sutton Surrey, SM2 5, United Kingdom
Local Institution - 0243
Cardiff , CF14 , United Kingdom
Local Institution - 0202
London , SE1 9, United Kingdom

How clear is this clinincal trial information?

Study is for people with:

Esophageal Cancer

Phase:

Phase 3

Estimated Enrollment:

794

Study ID:

NCT02743494

Recruitment Status:

Active, not recruiting

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.