Esophageal Cancer Clinical Trial
Effects of Oral Cancer Treatments on Upper Esophageal Opening During Swallowing
Summary
The purpose of this study is to investigate post-operative and post-radiation upper esophageal sphincter opening measures in oral cancer patients, compare measures to age- and gender-matched healthy adults, and determine relationships with patient swallowing outcomes and quality of life.
Eligibility Criteria
Inclusion Criteria:
Oral cancer that includes tongue or floor of mouth clinical stage T1 or higher
May have disease that extends to base of tongue or other site as long as floor of mouth or tongue are involved
Adults at least 18 years of age
Exclusion Criteria:
Oral cancer of the lip, cheek, palate or other site not impacting tongue or floor of mouth musculature
History of floor of mouth, tongue base, pharyngeal or laryngeal surgical resection
History of radiation treatment to the head and neck
History of dysphagia prior to onset of oral cancer symptoms
Allergy to lidocaine, barium, adhesive tape or apple flavoring
Woman of childbearing years who are pregnant
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