Esophageal Cancer Clinical Trial

Sentinel Lymph Node Mapping in Esophageal Cancer Using ICG Dye and NIR Imaging

Summary

The purpose of this study is to find out whether sentinel lymph node (SLN) mapping with ICG dye and NIR imaging can be used to identify esophageal or esophagogastric junction cancer that has spread to the lymph nodes. If SLN mapping is successful in these types of cancer, surgeons in the future could identify the sentinel lymph nodes and only remove these instead of removing all the lymph nodes which is currently done.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Pathological diagnosis of adenocarcinoma tumor located in distal 1/3 of esophagus or esophagogastric junction , with a plan to undergo minimally invasive esophagectomy.
All patients with Stage IVA (AJCC Cancer Staging Manual, 8th edition) disease will be eligible
≥18 years of age.
Documented, signed, and dated informed consent, obtained before any procedures, for the proposed research study and for standard surgical resection.

Exclusion Criteria:

No plan to undergo surgical resection.
Severe iodide or seafood allergy.
Women of childbearing potential without a negative pregnancy test; or women who are lactating.
Prior diagnosis of severe hepatic or renal dysfunction.
Patients with Stage IVB or M1 disease (AJCC Cancer Staging Manual, 8th edition)
Patients with local recurrence and planning to undergo salvage esophagectomy

Study is for people with:

Esophageal Cancer

Estimated Enrollment:

60

Study ID:

NCT04400292

Recruitment Status:

Recruiting

Sponsor:

Memorial Sloan Kettering Cancer Center

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There is 1 Location for this study

See Locations Near You

Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York New York, 10065, United States More Info
Daniela Molena, MD
Contact
212-639-3870

How clear is this clinincal trial information?

Study is for people with:

Esophageal Cancer

Estimated Enrollment:

60

Study ID:

NCT04400292

Recruitment Status:

Recruiting

Sponsor:


Memorial Sloan Kettering Cancer Center

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.