Heart Failure Clinical Trial
A Study of Ultra High Dose Diuretics to Treat Heart Failure
The purpose of this study is to determine the safety and effectiveness of ultrahigh dose diuretics compared to standard dose diuretics over 24 hours in patients with decompensated heart failure.
Diagnosis of decompensated heart failure receiving intravenous diuretics
Ability to provide informed consent
Patients on home inotrope medications
Patients with Chronic Kidney disease stage V and end stage renal failure on dialysis
Patients lacking the capacity to consent for themselves
Known pregnancy or breastfeeding mothers
Complex congenital heart disease
Allergy to furosemide or bumetanide
Respiratory failure requiring non-invasive ventilation (CPAP/BiPAP) or invasive mechanical ventilatory support at the time of randomization
Hypotension with systolic blood pressure <80 mm Hg at the time of randomization
Acute coronary syndrome
Sustained Ventricular tachycardia requiring treatment in the last 48 hours
Patients weighing ≤ 40 kg
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There is 1 Location for this study
Rochester Minnesota, 55905, United States
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