Heart Failure Clinical Trial

His Bundle Pacing in Bradycardia and Heart Failure

Summary

Participants in this study will either have heart failure (HF) and are scheduled to undergo pace maker (PM) implantation, cardiac resynchronization therapy pacemaker (CRT-P), cardiac resynchronization therapy defibrillator (CRT-D) implantation, His bundle pacing (HIBP) or left bundle area pacing (LBAP) (including HIBP/LBAP for patients with HF, for patients who have failed CRT implant or patients who are CRT non-responders), or have atrioventricular (AV) block or bradycardia and are scheduled to undergo dual chamber pacemaker implantation. In this study additional heart rhythm measurements will be collected during the implant procedure to better understand how His bundle and/or parahisian pacing (HISP) effects electrical conduction in the hearts of patients with HF or AV block.

The hypothesis is that His bundle or parahisian pacing (HISP) and left bundle area pacing (LBAP) may normalize atrioventricular (AV) conduction with a narrow combination of the Q wave, R wave and S wave (QRS complex) in functional bundle branch block or conduction delay in patients with heart failure (HF).

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

HF Group

Clinically recommended to undergo PM, CRT-P, or CRT-D implantation or HIBP/LBAP (including HIBP/LBAP for patients with HF, for patients who have failed CRT implant or patients who are CRT non-responders)
Any QRS duration
LVEF ≤ 50%

AV Block/Bradycardia Group

Recommended to undergo dual chamber pacemaker implantation
Second or third degree AV block or Sinus Bradycardia

Exclusion Criteria:

Age < 18 years
Pregnant

Study is for people with:

Heart Failure

Estimated Enrollment:

80

Study ID:

NCT03008291

Recruitment Status:

Recruiting

Sponsor:

Yong-Mei Cha

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There is 1 Location for this study

See Locations Near You

Mayo Clinic
Rochester Minnesota, 55905, United States More Info
Yong-mei Cha
Contact
507-255-2440
[email protected]
Brian Liddel
Contact
(507) 255-8717
[email protected]
Yong-Mei Cha
Principal Investigator

How clear is this clinincal trial information?

Study is for people with:

Heart Failure

Estimated Enrollment:

80

Study ID:

NCT03008291

Recruitment Status:

Recruiting

Sponsor:


Yong-Mei Cha

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.