Heart Failure Clinical Trial

Clinical Trial Finder Heart Failure Trials

Study to Evaluate Safety, Tolerability and Drug Levels of BMS-986435/MYK-224 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

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Summary

The purpose of this study is to evaluate the safety, tolerability, and exposure-response (E-R) of BMS-986435/MYK-224 in participants with symptomatic Heart Failure with Preserved Ejection Fraction (HFpEF).

View Eligibility Criteria

Eligibility Criteria

Key Inclusion Criteria:

Adult participants with stable, symptomatic HFpEF with a normal heart pumping ability

Key Exclusion Criteria:

Participants must not have a known diagnosis of obstructive or genetic hypertrophic cardiomyopathy or infiltrative/storage disorder such as cardiac amyloidosis, or any other acute or serious condition that could interfere with assessments during the study or may pose a risk to the participant

Note: Other protocol-defined inclusion/exclusion criteria apply

Study is for people with:

Heart Failure

Phase:

Phase 2

Estimated Enrollment:

48

Study ID:

NCT06122779

Recruitment Status:

Recruiting

Sponsor:

Bristol-Myers Squibb

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There are 28 Locations for this study

See Locations Near You

Emory Heart and Vascular Center
Atlanta Georgia, 30322, United States More Info
Alanna Morris, Site 0014
Contact
Emory Heart and Vascular Center
Atlanta Georgia, 30322, United States More Info
Alanna Morris, Site 0048
Contact
Chicago Medical Research, LLC
Hazel Crest Illinois, 60429, United States More Info
Suhail Khadra, Site 0005
Contact
708-798-8522
St Vincent Hospital and Health Care Centers Inc
Indianapolis Indiana, 46260, United States More Info
Ashwin Ravichandran, Site 0045
Contact
317-338-8042
St. Vincent Hospital And Health Care Center, Inc.
Indianapolis Indiana, 46260, United States More Info
Ashwin Ravichandran, Site 0029
Contact
317-338-8042
St. Louis Heart and Vascular
Saint Louis Missouri, 63136, United States More Info
Harvey Serota, Site 0028
Contact
314-577-8896
St. Louis Heart and Vascular
Saint Louis Missouri, 63136, United States More Info
Harvey Serota, Site 0043
Contact
314-577-8896
South Oklahoma Heart Research
Oklahoma City Oklahoma, 73135, United States More Info
Naeem Tahirkheli, Site 0041
Contact
405-628-6865
South Oklahoma Heart Research
Oklahoma City Oklahoma, 73135, United States More Info
Naeem Tahirkheli, Site 0016
Contact
405-628-6865
Tennessee Center for Clinical Trials
Tullahoma Tennessee, 37388, United States More Info
Dinesh Gupta, Site 0001
Contact
931-461-2663
Clinical Heart and Vascular Center
Dallas Texas, 75390, United States More Info
Ambarish Pandey, Site 0036
Contact
214-645-8000
Angiocardiac Care of Texas - PA - PPDS
Houston Texas, 77025, United States More Info
Amin Karim, Site 0051
Contact
281-944-3610
Angiocardiac Care Of Texas
Houston Texas, 77025, United States More Info
Amin Karim, Site 0015
Contact
281-944-3610
Local Institution - 0037
Toronto Ontario, M4P 1, Canada More Info
Site 0037
Contact
Local Institution - 0030
Toronto Ontario, M5S 1, Canada More Info
Site 0030
Contact
Local Institution - 0040
Toronto Ontario, M5S 1, Canada More Info
Site 0040
Contact
Local Institution - 0035
Trois-Rivieres Quebec, G9A 1, Canada More Info
Site 0035
Contact
Local Institution - 0019
Napoli Campania, 80131, Italy More Info
Site 0019
Contact
Local Institution - 0022
Melegnano Lombardia, 20077, Italy More Info
Site 0022
Contact
Local Institution - 0023
Milano Lombardia, 20162, Italy More Info
Site 0023
Contact
Local Institution - 0033
Milano Lombardia, 20162, Italy More Info
Site 0033
Contact
Local Institution - 0050
San Donato Milanese Lombardia, 20097, Italy More Info
Site 0050
Contact
Local Institution - 0027
Foggia Puglia, 71100, Italy
Local Institution - 0038
Foggia Puglia, 71100, Italy More Info
Site 0038
Contact
Local Institution - 0052
Massa Toscana, 54100, Italy More Info
Site 0052
Contact
Local Institution - 0017
Pisa Toscana, 56124, Italy More Info
Site 0017
Contact
Local Institution - 0020
Lublin Lubelskie, 20-95, Poland More Info
Site 0020
Contact
Local Institution - 0031
Bialystok Podlaskie, 15-27, Poland More Info
Site 0031
Contact
Local Institution - 0044
Bialystok Podlaskie, 15-27, Poland More Info
Site 0044
Contact
Local Institution - 0006
Krakow , 30-08, Poland
Local Institution - 0049
Lublin , 20-95, Poland More Info
Site 0049
Contact
Local Institution - 0024
Oswiecim , 51162, Poland More Info
Site 0024
Contact
Local Institution - 0025
Majadahonda Madrid, 28222, Spain More Info
Site 0025
Contact
Local Institution - 0047
Majadahonda Madrid, 28222, Spain More Info
Site 0047
Contact
Local Institution - 0039
El Palmar Murcia, 30120, Spain More Info
Site 0039
Contact
Local Institution - 0042
Malaga Málaga, 29010, Spain More Info
Site 0042
Contact
Local Institution - 0032
a Gudina Ourense, 32540, Spain More Info
Site 0032
Contact
Local Institution - 0026
Madrid , 28034, Spain More Info
Site 0026
Contact
Local Institution - 0034
Madrid , 28034, Spain More Info
Site 0034
Contact
Local Institution - 0021
Murcia , 30120, Spain More Info
Site 0021
Contact
Local Institution - 0018
Sevilla , 41014, Spain More Info
Site 0018
Contact
Local Institution - 0046
Sevilla , 41014, Spain More Info
Site 0046
Contact
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How clear is this clinincal trial information?

Study is for people with:

Heart Failure

Phase:

Phase 2

Estimated Enrollment:

48

Study ID:

NCT06122779

Recruitment Status:

Recruiting

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

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