Kidney Cancer Clinical Trial
Axitinib (AG-013736) With Or Without Dose Titration (Increase) In Patients With Kidney Cancer
Summary
Axitinib dose titration (giving a higher dose of the drug above its standard starting dose) among certain patients may improve the response to treatment.
Eligibility Criteria
Inclusion Criteria:
metastatic renal cell carcinoma (kidney cancer) with clear cell component
no prior systemic therapy (including no prior adjuvant or neoadjuvant)
Eastern Cooperative Oncology Group (ECOG) Performance Status 0-1
Blood Pressure < or = 140/90mmHg
Exclusion Criteria:
brain/CNS metastasis
using more than 2 blood pressure medications
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There are 58 Locations for this study
Antioch California, 94531, United States
Bakersfield California, 93309, United States
Pleasant Hill California, 94523, United States
Pleasant Hill California, 94523, United States
Pleasant Hill California, 94523, United States
San Leandro California, 94578, United States
Tampa Florida, 33612, United States
Indianapolis Indiana, 46202, United States
Indianapolis Indiana, 46202, United States
Indianapolis Indiana, 46202, United States
Baltimore Maryland, 21201, United States
Baltimore Maryland, 21231, United States
Baltimore Maryland, 21287, United States
Boston Massachusetts, 02114, United States
Boston Massachusetts, 02215, United States
Grand Rapids Michigan, 49503, United States
Saint Louis Missouri, 63110, United States
Saint Louis Missouri, 63110, United States
Omaha Nebraska, 68114, United States
Omaha Nebraska, 68198, United States
Las Vegas Nevada, 89135, United States
Cincinnati Ohio, 45219, United States
Cincinnati Ohio, 45219, United States
Cleveland Ohio, 44195, United States
Columbus Ohio, 43210, United States
Columbus Ohio, 43221, United States
West Chester Ohio, 45069, United States
Portland Oregon, 97239, United States
Dallas Texas, 75246, United States
Houston Texas, 77030, United States
Seattle Washington, 98101, United States
Brno CZE, 656 5, Czechia
Olomouc , 775 2, Czechia
Praha 8 , 180 8, Czechia
Usti nad Labem , 401 1, Czechia
Duesseldorf , 40225, Germany
Frankfurt , 60590, Germany
Hannover , 30625, Germany
Tuebingen , 72076, Germany
Weiden , 92637, Germany
Nagoya Aichi, 466-8, Japan
Sapporo Hokkaido, 060-8, Japan
Sapporo Hokkaido, 060-8, Japan
Kobe Hyogo, 650-0, Japan
Osakasayama Osaka, 589-8, Japan
Hamamatsu-City Shizuoka, 431-3, Japan
Chuo-ku Tokyo, 104-0, Japan
Koto-ku Tokyo, 135-8, Japan
Shinjuku-ku Tokyo, 160-8, Japan
Akita , 010-8, Japan
Chiba , 260-8, Japan
Fukuoka , 812-8, Japan
Nagasaki , 852-8, Japan
Tokushima , 770-8, Japan
Yamagata , 990-9, Japan
Obninsk Kaluga Region, 24903, Russian Federation
Poselok Kuzmolovskiy Vsevolozhskiy Region, Leningradskaya Oblast, 18866, Russian Federation
Moscow , 11547, Russian Federation
Moscow , 11799, Russian Federation
Saint-Petersburg , 19702, Russian Federation
Saint-Petersburg , 19825, Russian Federation
Samara , 44303, Russian Federation
Madrid , 28006, Spain
Madrid , 28007, Spain
Madrid , 28046, Spain
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