Kidney Cancer Clinical Trial

Evaluating Renal Masses Using Ultrasound Intravenous Microbubble Contrast

Summary

The purpose of this study is to evaluate the blood flow in kidney masses by using ultrasound microbubble contrast material, and to see if results from ultrasound contrast studies can predict if a kidney mass is benign or malignant. Patterns of blood flow in the kidney mass will be examined to see if:

benign kidney masses can be distinguished from kidney cancers and
if slow growing, lower risk cancers have different blood flow compared to clear cell cancer which is the most common type of kidney cancer.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Any adult patient who is planned or scheduled for surgical excision or biopsy of a solid or complex cystic renal mass would be eligible for the study
Histology of the renal mass must be unknown at the time of enrollment
Patients who have renal masses that are evident on conventional US imaging
Patients will have a correlative abdominal CT and/or MRI

Exclusion Criteria:

Patients with any history of cardiac shunts.
Patients with history of pulmonary hypertension or unstable cardiopulmonary conditions, including patients on mechanical ventilation.
Patients without peripheral IV access
Pregnant patients and children
Patients with any known contrast allergies, allergy to perflutren, or any components of Definity or microbubble contrast
Patients who have renal masses that are not evident on conventional US imaging

Study is for people with:

Kidney Cancer

Phase:

Phase 1

Estimated Enrollment:

42

Study ID:

NCT00671411

Recruitment Status:

Completed

Sponsor:

Memorial Sloan Kettering Cancer Center

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There is 1 Location for this study

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Memorial Sloan-Kettering Cancer Center
New York New York, 10065, United States

How clear is this clinincal trial information?

Study is for people with:

Kidney Cancer

Phase:

Phase 1

Estimated Enrollment:

42

Study ID:

NCT00671411

Recruitment Status:

Completed

Sponsor:


Memorial Sloan Kettering Cancer Center

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