Kidney Cancer Clinical Trial
Study of BMS-986315 Alone and in Combination With Nivolumab or Cetuximab in Participants With Advanced Solid Tumors
The purpose of this study is to evaluate BMS-986315 alone and in combination with nivolumab or cetuximab in participants with advanced solid tumors.
Participants must have histologic confirmation of advanced (metastatic, recurrent, and/or unresectable) squamous cell carcinoma of the head and neck (SCCHN), nonsmall cell lung cancer (NSCLC), or renal cell cancer (RCC) with measurable disease per RECIST 1.1
Participants expected to have received standard of care therapies including an available PD-(L)1 inhibitor
Eastern cooperative oncology group performance status of 0 or 1
Women of childbearing potential must agree to follow methods of contraception
Participants with active, known or suspected autoimmune disease
Participants with a condition requiring systemic treatment with either corticosteroids or other immunosuppressive medications
Uncontrolled or significant cardiovascular disease
History of or with active interstitial lung disease or pulmonary fibrosis
Prior participation in anti-natural killer cell receptor (anti-NKG2A) clinical study
History of allergy or hypersensitivity to study drug components
Other protocol-defined inclusion/exclusion criteria apply
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There are 14 Locations for this study
Gilbert Arizona, 85234, United States
Baltimore Maryland, 21287, United States
Winston-Salem North Carolina, 27157, United States
Capital Federal Distrito Federal, C1428, Argentina
Edmonton Alberta, T6X 1, Canada More Info
Vancouver British Columbia, V5Z 4, Canada More Info
Vancouver British Columbia, V5Z 4, Canada
Ottawa Ontario, K1H 8, Canada
Toronto Ontario, M5G 2, Canada More Info
Montreal Quebec, H2X 3, Canada More Info
Ottawa , K1H 8, Canada More Info
Recoleta Metropolitana, , Chile
Mexico city Distrito Federal, 06100, Mexico More Info
Monterrey Nuevo LEON, 66460, Mexico
San Luis Potosí SAN LUIS Potosi, 78250, Mexico
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