Lung Cancer Clinical Trial
A Randomized Trial Of PF-00299804 Taken Orally Versus Erlotinib Taken Orally For Treatment Of Advanced Non-Small Cell Lung Cancer That Has Progressed After One Or Two Prior Chemotherapy Regimen
Summary
This study will compare PF-00299804 given orally on continuous schedule to the approved drug, erlotinib, in patients whose non-small cell lung cancer has progressed after chemotherapy; patients will be randomized to receive one of these drugs, and followed for efficacy and tolerance of each.
Eligibility Criteria
Inclusion Criteria:
advanced measurable Non-Small Cell Lung Cancer (NSCLC);
progressed after 1-2 prior chemotherapy;
Eastern Cooperative Oncology Group (ECOG) 0-2;
tissue available for future KRAS/ EGFR testing
Exclusion Criteria:
prior Epidermal Growth Factor Receptor (EGFR) targeted therapy;
active or untreated Central Nervous System (CNS) metastases;
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There are 53 Locations for this study
Muscle Shoals Alabama, 35661, United States
Montebello California, 90640, United States
Bridgeport Connecticut, 06610, United States
Norwalk Connecticut, 06856, United States
Waterbury Connecticut, 06708, United States
Atlanta Georgia, 30303, United States
Atlanta Georgia, 30322, United States
Atlanta Georgia, 30322, United States
Atlanta Georgia, 30322, United States
Atlanta Georgia, 30322, United States
Augusta Georgia, 30901, United States
Augusta Georgia, 30909, United States
Columbus Georgia, 31904, United States
Decatur Georgia, 30033, United States
Gainesville Georgia, 30501, United States
Macon Georgia, 31201, United States
Marietta Georgia, 30106, United States
Warner Robins Georgia, 31088, United States
Post Falls Idaho, 83854, United States
Post Falls Idaho, 83854, United States
Zion Illinois, 60099, United States
Bethesda Maryland, 20817, United States
Rockville Maryland, 20850, United States
Minneapolis Minnesota, 55455, United States
Memphis Tennessee, 38120, United States
Clarksburg West Virginia, 26301, United States
Camperdown New South Wales, 2050, Australia
Fitzroy Victoria, 3065, Australia
Geelong Victoria, 3220, Australia
Wodonga Victoria, 3690, Australia
Porto Alegre RS, 90050, Brazil
Porto Alegre RS, 90610, Brazil
Barretos SP, 14784, Brazil
Sao Paulo SP, 01246, Brazil
Vancouver British Columbia, V5Z 4, Canada
Barrie Ontario, L4M 6, Canada
Oshawa Ontario, L1G 2, Canada
Ottawa Ontario, K1H 8, Canada
Shatin New Territories, , Hong Kong
Tuen Mun New Territories, , Hong Kong
Seoul , 110-7, Korea, Republic of
Seoul , 120-7, Korea, Republic of
Seoul , 135-7, Korea, Republic of
Chrzanow , 32-50, Poland
Krakow , 30-04, Poland
Krakow , 31-10, Poland
Krakow , 31-21, Poland
Warsaw , 02-78, Poland
Warszawa , 00-72, Poland
Ponce , 00716, Puerto Rico
Singapore , 16961, Singapore
Badalona Barcelona, 08916, Spain
Palma de Mallorca Islas Baleares, 07198, Spain
Barakaldo Vizcaya, 48903, Spain
La Coruña , 15006, Spain
Taipei , 100, Taiwan
Taipei , 112, Taiwan
Manchester , M20 4, United Kingdom
Oxford , OX3 7, United Kingdom
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