Lung Cancer Clinical Trial

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A Safety And Efficacy Study Of The Combination Of Oral PF-00299804 And Intravenous CP-751,871 Given Every 3 Weeks

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Summary

This study will explore the combination of the oral drug PF-00299804 and intravenous CP-751,871 in patients with advanced solid tumor. Each of these drugs have been given separately to patients in prior studies, and this study is to establish the safety and efficacy of the combination.

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Eligibility Criteria

Inclusion Criteria:

Histologically documented advanced cancer, Eastern Cooperative Oncology Group (ECOG) 0-1;
Platelets > 100,000, ANC > 1500;
Ccr > 60 or serum creat. <1.5
Non-small cell cancer cohort:
Eastern Cooperative Oncology Group (ECOG) 0-2, prior platin, < 4 prior chemotherapy regimen
HgA1C <5.7%

Exclusion Criteria:

Active Central Nervous System (CNS) metastases;
prior IGF1-R targeted therapy
Any history of unstable angina, myocardial infarction or symptomatic congestive heart failure.

Study is for people with:

Lung Cancer

Phase:

Phase 1

Estimated Enrollment:

74

Study ID:

NCT00728390

Recruitment Status:

Completed

Sponsor:

Pfizer

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There are 5 Locations for this study

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Pfizer Investigational Site
Amherst New York, 14221, United States
Pfizer Investigational Site
Buffalo New York, 14263, United States
Pfizer Investigational Site
San Antonio Texas, 78229, United States
Pfizer Investigational Site
Villejuif , 94805, France
Pfizer Investigational Site
Madrid , 28050, Spain
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How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 1

Estimated Enrollment:

74

Study ID:

NCT00728390

Recruitment Status:

Completed

Sponsor:


Pfizer

How clear is this clinincal trial information?

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