Airway Epithelium Gene Expression in the Diagnosis of Lung Cancer: AEGIS CLIA

Inclusion Criteria:

The patient is being evaluated for the diagnosis of possible lung cancer or "rule out lung cancer" and is indicated for bronchoscopy.
The patient is undergoing bronchoscopy
≥ 21 years of age
Patient meets local site's standard of care (SOC) for performing diagnostic bronchoscopy
The patient is a current or former cigarette smoker (defined as having smoked >100 cigarettes in their lifetime.

Exclusion Criteria:

The Pulmonary physician does not recommend that bronchoscopy be performed
The patient is unable to be consented into the study or unable to comply with requirements of the study
The patient has previously been diagnosed with primary lung cancer
Immediately prior to bronchoscopy, the patient has been on a mechanical ventilator for ≥ 24 consecutive hours.