Lung Cancer Clinical Trial

Clinical Trial Finder Lung Cancer Trials

An Investigational Immuno-therapy Study for Safety of Nivolumab in Combination With Ipilimumab to Treat Advanced Cancers

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Summary

A study to evaluate the safety of Nivolumab given in combination with Ipilimumab in patients with advanced cancers. The initial group will enroll patients with newly diagnosed Stage 4 or non-small cell lung cancer that has come back.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Histologically confirmed Stage 4 or recurrent non-small cell lung cancer
Eastern Cooperative Oncology Group (ECOG) score 0-1 (Physically able to carry out light housework or office work through to being fully active as you were before cancer)
No prior systemic anticancer therapy (including EGFR and ALK inhibitors)
Tissue or Programmed death-ligand 1 (PD-L1) results available

Cohort 1A Inclusion Criteria:

Eastern Cooperative Oncology Group (ECOG) score 2 or
Eastern Cooperative Oncology Group (ECOG) score 0-1 and one disease specific criteria as listed in the protocol

Cohort C Inclusion Criteria:

High Tumor Mutation Burden

Exclusion Criteria:

Untreated brain metastases
An active malignancy that requires concurrent intervention
Active, known or suspected autoimmune disease
Carcinomatous meningitis, which means there is inflammation of the covering of the brain, caused by cancer

Other protocol-defined inclusion/exclusion criteria apply

Study is for people with:

Lung Cancer

Phase:

Phase 4

Estimated Enrollment:

1036

Study ID:

NCT02869789

Recruitment Status:

Completed

Sponsor:

Bristol-Myers Squibb

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There are 133 Locations for this study

See Locations Near You

Local Institution - 0121
Birmingham Alabama, 35205, United States
Local Institution - 0148
Phoenix Arizona, 85016, United States
Local Institution - 0085
Tucson Arizona, 85704, United States
Local Institution - 0164
Little Rock Arkansas, 72205, United States
Local Institution - 0146
Bakersfield California, 93309, United States
Marin Cancer Care, Inc
Greenbrae California, 94904, United States
Los Angeles Hematology/Oncology Medical Group
Los Angeles California, 90017, United States
Local Institution - 0115
Los Angeles California, 90095, United States
Torrance Health Association
Redondo Beach California, 90277, United States
Va San Diego Healthcare System
San Diego California, 92161, United States
Local Institution - 0143
San Luis Obispo California, 93401, United States
Local Institution - 0144
Santa Maria California, 93454, United States
Gene Upshaw Memorial Tahoe Forest Cancer Center
Truckee California, 96161, United States
Local Institution - 0161
Whittier California, 90603, United States
Local Institution - 0083
Denver Colorado, 80218, United States
Local Institution - 0141
Grand Junction Colorado, 81501, United States
Cancer Specialists of North FL
Jacksonville Florida, 32207, United States
Local Institution - 0082
Ocala Florida, 34474, United States
Local Institution - 0147
Pembroke Pines Florida, 33028, United States
Local Institution - 0163
Athens Georgia, 30607, United States
Local Institution - 0002
Atlanta Georgia, 30322, United States
Local Institution - 0166
Atlanta Georgia, 30342, United States
Local Institution - 0088
Niles Illinois, 60714, United States
Local Institution - 0108
Wichita Kansas, 67214, United States
Kentucky One Health St. Joseph East Cancer Center
Lexington Kentucky, 40509, United States
Local Institution - 0091
Columbia Maryland, 21044, United States
Local Institution - 0089
Edina Minnesota, 55435, United States
Jackson Oncology Associates, Pllc
Jackson Mississippi, 39202, United States
Local Institution - 0077
Grand Island Nebraska, 68803, United States
Local Institution - 0087
Las Vegas Nevada, 89148, United States
Local Institution - 0170
Reno Nevada, 89511, United States
Local Institution - 0156
Belleville New Jersey, 07109, United States
Summit Medical Group
Florham Park New Jersey, 07932, United States
Local Institution - 0142
Livingston New Jersey, 07039, United States
Local Institution - 0167
Bronx New York, 10461, United States
Local Institution - 0004
Durham North Carolina, 27710, United States
Local Institution - 0012
Winston-Salem North Carolina, 27157, United States
Local Institution - 0100
Cincinnati Ohio, 45242, United States
Local Institution - 0134
Cleveland Ohio, 44109, United States
Local Institution - 0172
Corvallis Oregon, 97330, United States
Local Institution - 0096
Eugene Oregon, 97401, United States
Local Institution - 0176
Portland Oregon, 97239, United States
Local Institution - 0139
Allentown Pennsylvania, 18103, United States
Allegheny Health Network
Pittsburgh Pennsylvania, 15224, United States
Local Institution - 0159
Pittsburgh Pennsylvania, 15232, United States
Local Institution - 0001
Sayre Pennsylvania, 18840, United States
Local Institution - 0123
Charleston South Carolina, 29414, United States
Local Institution - 0066
Chattanooga Tennessee, 37404, United States
Local Institution - 0067
Nashville Tennessee, 37203, United States
Local Institution - 0090
Austin Texas, 78745, United States
Texas Oncology, P.A.
Dallas Texas, 75230, United States
Local Institution - 0149
Dallas Texas, 75231, United States
Local Institution - 0094
Fort Worth Texas, 76104, United States
Local Institution - 0093
Longview Texas, 75601, United States
Local Institution - 0098
Plano Texas, 75075, United States
Local Institution - 0086
Waco Texas, 76712, United States
Local Institution - 0097
Fairfax Virginia, 22031, United States
Local Institution - 0044
Richmond Virginia, 23230, United States
Providence Regional Cancer Partnership
Everett Washington, 98201, United States
Local Institution - 0174
Renton Washington, 98055, United States
Local Institution - 0173
Spokane Washington, 99208, United States
Local Institution - 0008
Capital Federal Buenos Aires, 1426, Argentina
Local Institution - 0006
Viedma RIO Negro, 8500, Argentina
Local Institution - 0007
Caba , 1199, Argentina
Local Institution - 0009
Cordoba , 5000, Argentina
Local Institution - 0126
Tucuman , 4000, Argentina
Local Institution - 0038
Gent , 9000, Belgium
Local Institution - 0037
Liege , 4000, Belgium
Local Institution - 0036
Sint-Niklaas , 9100, Belgium
Local Institution - 0152
Ijui RIO Grande DO SUL, 98700, Brazil
Local Institution - 0154
Porto Alegre RIO Grande DO SUL, 90610, Brazil
Local Institution - 0153
Porto Alegre RIO Grande DO SUL, 91350, Brazil
Local Institution - 0151
Barretos Sao Paulo, 14780, Brazil
Local Institution - 0127
Greenfield Park Quebec, J4V 2, Canada
Local Institution - 0109
Montreal Quebec, H4J 1, Canada
Local Institution - 0049
Rimouski Quebec, G5L 5, Canada
Local Institution - 0050
Trois-Rivieres Quebec, G8Z 3, Canada
Local Institution - 0010
Santiago Metropolitana, 84203, Chile
Local Institution - 0011
Santiago , , Chile
Local Institution - 0133
Novy Jicin , 741 0, Czechia
Local Institution - 0130
Praha 2 , 128 0, Czechia
Local Institution - 0118
Bordeaux , 33076, France
Local Institution - 0075
Dijon Cedex , 21079, France
Local Institution - 0069
Marseille Cedex 20 , 13915, France
Local Institution - 0076
Paris , 75018, France
Local Institution - 0074
Pessac cedex , 33604, France
Local Institution - 0071
Rennes Cedex 9 , 35033, France
Local Institution - 0070
Saint Herblain , 44805, France
Local Institution - 0072
Strasbourg Cedex , 67091, France
Local Institution - 0073
Toulon Cedex , 83056, France
Local Institution - 0023
Frankfurt , 60488, Germany
Local Institution - 0028
Gera , 07548, Germany
Local Institution - 0029
Kassel , 34125, Germany
Local Institution - 0026
Loewenstein , 74245, Germany
Local Institution - 0025
Wiesbaden , 65199, Germany
Local Institution - 0030
Athens , 11527, Greece
Local Institution - 0031
N. Faliro , 18547, Greece
Local Institution - 0032
Thessaloniki , 56429, Greece
Local Institution - 0013
Gyöngyös - Mátraháza Heves, 3233, Hungary
Local Institution - 0014
Budapest , 1083, Hungary
Local Institution - 0054
Milan Lombardia, 20141, Italy
Ospedale Policlinico San Martino
Genova , 16132, Italy
IRST Meldola
Meldola , 47014, Italy
AOU della Campania Luigi Vanvitelli
Napoli , 80131, Italy
Local Institution
Napoli , 80131, Italy
Ospedale Degli Infermi
Rimini , 47923, Italy
Azienda Ospedaliera Universitaria Senese
Siena , 53100, Italy
Azienda Ospedaliera Santa Maria Terni
Terni , 05100, Italy
Local Institution - 0019
Monterrey, NL , 64060, Mexico
Local Institution - 0045
Groningen , 9714 , Netherlands
Local Institution - 0035
Rotterdam , 3014 , Netherlands
Local Institution - 0015
Bydgoszcz , 85-79, Poland
Local Institution - 0068
Sucha Beskidzka , 34-20, Poland
Local Institution - 0016
Warszawa , 02-78, Poland
Local Institution - 0128
Bucuresti , 02138, Romania
Local Institution - 0119
Craiova , 20034, Romania
Local Institution - 0120
Romania , 40001, Romania
Local Institution - 0022
Moscow , 11547, Russian Federation
Local Institution - 0021
Moscow , 12130, Russian Federation
Local Institution - 0020
St Petersburg , 19825, Russian Federation
Local Institution - 0061
A Coruña , 15006, Spain
Local Institution - 0060
Barcelona , 08035, Spain
Local Institution - 0062
Jaen , 23007, Spain
Local Institution - 0065
Madrid , 28041, Spain
Local Institution - 0064
Majadahonda - Madrid , 28222, Spain
Local Institution - 0063
Sevilla , 41013, Spain
Local Institution - 0059
Valencia , 46026, Spain
Local Institution - 0112
Zaragoza , 50009, Spain
Local Institution - 0048
Basel , 4031, Switzerland
Local Institution - 0046
Zuerich , 8091, Switzerland
Local Institution - 0104
Antalya , 07070, Turkey
Local Institution - 0041
London Greater London, SE1 9, United Kingdom
Local Institution - 0039
Leicester Leicestershire, LE1 5, United Kingdom
Local Institution - 0040
Edinburgh Midlothian, EH4 2, United Kingdom
Local Institution - 0043
Newcastle Upon Tyne , NE7 7, United Kingdom
Local Institution - 0042
Wirral , CH63 , United Kingdom
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How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 4

Estimated Enrollment:

1036

Study ID:

NCT02869789

Recruitment Status:

Completed

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

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