Clinical Impact of EUS in Staging NSCLC

Inclusion Criteria:

Any subject with presumed or known potentially resectable NSCLC
Due to the nature of NSCLC, children (<18 year of age) will not be considered
Men, women, and minorities
Subjects must be able to safely undergo conscious sedation for the EUS procedure
Subjects must be surgical candidates
Subjects must not have an uncorrectable coagulopathy and must be able to refrain from the used of aspirin one week prior to the EUS
Patient must provide signed written informed consent

Exclusion Criteria:

Subjects with a history of previously treated lung, head & neck, or esophageal cancer are not eligible if the histologic cell type is determined to be the same as what is biopsied during the EUS-FNA
Uncorrectable coagulopathy
Significant co-morbidities such as uncontrolled heart failure, or severe chronic obstructive pulmonary disease (COPD) that would limit their survivability to surgery
Evidence of significant active infection (e.g. pneumonia, peritonitis, wound abscess)
Evidence of serious ongoing illness such as uncontrolled metabolic disease (diabetes mellitus, hypothyroidism, etc.) or cardiac condition
Evidence of dementia or altered mental status that would prohibit the giving and understanding of informed consent, and no evidence of psychiatric illness that would preclude adequate compliance with this protocol