Lung Cancer Clinical Trial
Effectiveness Study of Nivolumab Compared to Chemotherapy in Patients With Relapsed Small-cell Lung Cancer
Summary
The purpose of this study is to compare the overall survival of nivolumab versus chemotherapy in subjects with relapsed SCLC.
Eligibility Criteria
Inclusion Criteria:
Histologically or cytologically confirmed small cell lung cancer (SCLC)
Subjects with either limited or extensive disease stage at the initial diagnosis
Must have recurrence or progression after platinum-based first-line chemotherapy or chemoradiation therapy for the treatment of limited or extensive disease stage SCLC
Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
Exclusion Criteria:
Untreated or symptomatic central nervous system (CNS) metastases
Prior therapy with anti-PD-1, anti-PDL1, anti-PD-L2, anti-CD137, or anti-CTLA-4 antibody
Inadequate hematologic or hepatic function
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There are 145 Locations for this study
Little Rock Arkansas, 72205, United States
New Haven Connecticut, 06520, United States
Atlanta Georgia, 30322, United States
Saint Louis Missouri, 63110, United States
Lincoln Nebraska, 68506, United States
Johnson City New York, 13790, United States
Durham North Carolina, 27710, United States
Cleveland Ohio, 44106, United States
Bethlehem Pennsylvania, 18015, United States
Lancaster Pennsylvania, 17604, United States
Philadelphia Pennsylvania, 19111, United States
Nashville Tennessee, 37203, United States
Nashville Tennessee, 37232, United States
Kennewick Washington, 99336, United States
Waratah New South Wales, 2298, Australia
Brisbane Queensland, 4032, Australia
Elizabeth Vale South Australia, 5112, Australia
Kurralta Park South Australia, 5037, Australia
Perth Western Australia, 6150, Australia
Murdoch , 6150, Australia
Graz , 8036, Austria
Wels , 4600, Austria
Wien , 1090, Austria
Bruxelles , 1200, Belgium
Edegem , 2650, Belgium
Leuven , 3000, Belgium
Yvoir , 5530, Belgium
Ijui RIO Grande DO SUL, 98700, Brazil
Porto Alegre Rio Grande Do Sul, 90610, Brazil
Barretos Sao Paulo, 14784, Brazil
Sao Paulo , 01321, Brazil
Recoleta Santiago De Chile, , Chile
Beijing Beijing, 10000, China
Beijing Beijing, 10002, China
Beijing Beijing, 10003, China
Beijing Beijing, 10114, China
Guanzhou Guangdong, 51008, China
Zhengzhou Henan, 45000, China
Nanjing Jiangsu, 21000, China
Changchun Jilin, 13001, China
Xian Shaanxi, 71003, China
Shanghai Shanghai, 20002, China
Shanghai Shanghai, 20003, China
Urumqi Xinjiang, 83001, China
Hangzhou Zhejiang, 31002, China
Beijing , 10007, China
Guangzhou , , China
Hangzhou , 31001, China
Shanghai , 20003, China
Brno , 625 0, Czechia
Brno , 656 5, Czechia
Olomouc , 779 0, Czechia
Praha 4 , 14059, Czechia
Copenhagen , 2100, Denmark
Herlev , 2730, Denmark
Odense , 5000, Denmark
Brest , 29200, France
Lille Cedex , 59037, France
Paris Cedex 14 , 75014, France
Pringy Cedex , 74374, France
Reims , 51100, France
Toulon Cedex , 83056, France
Bamberg , 96049, Germany
Berlin , 13125, Germany
Essen , 45122, Germany
Frankfurt am Main , 60590, Germany
Gera , 07548, Germany
Gerlingen , 70839, Germany
Grosshansdorf , 22927, Germany
Halle (saale) , 06120, Germany
Hamburg , 21075, Germany
Heidelberg , 69126, Germany
Immenstadt , 87509, Germany
Koeln , 50937, Germany
Muenchen , 81925, Germany
Oberhausen , 46145, Germany
Regensburg , 93053, Germany
Heraklion Creta, 71110, Greece
Athens , 11527, Greece
Thessaloniki , 56429, Greece
Budapest , 1083, Hungary
Budapest , 1121, Hungary
Beer Sheva , 84101, Israel
Kfar Saba , , Israel
Ramat -Gan , 52621, Israel
Safed , 13100, Israel
Bologna , 40139, Italy
Livorno , 57100, Italy
Lucca , 55100, Italy
Meldola , 47014, Italy
Milano , 20133, Italy
Monza , 20052, Italy
Rimini , 47923, Italy
Roma , 00189, Italy
Nagoya-shi Aichi, 46486, Japan
Nagoya Aichi, 460-0, Japan
Kashiwa Chiba, 277-8, Japan
Matsuyama Ehime, 79102, Japan
Fukuoka-shi Fukuoka, 811-1, Japan
Akashi-shi Hyogo, 67385, Japan
Kobe Hyogo, 65000, Japan
Natori-shi Miyagi, 98112, Japan
Niigata-shi Niigata, 951-8, Japan
Habikino-shi Osaka, 58385, Japan
Hirakata-shi Osaka, 57311, Japan
Osaka-sayama Osaka, 589-8, Japan
Osaka-shi Osaka, 53400, Japan
Sakai Osaka, 591-8, Japan
Kitaadachi-gun Saitama, 362-0, Japan
Bunkyo-ku Tokyo, 11384, Japan
Chuo-ku Tokyo, 10400, Japan
Chuo-ku Tokyo, 54185, Japan
Wakayama-Shi Wakayama, 641-8, Japan
Tokyo , 135-8, Japan
Suwon Gyeonggi-do, 16247, Korea, Republic of
Cheongju-si , 28644, Korea, Republic of
Seoul , 02841, Korea, Republic of
Seoul , 05505, Korea, Republic of
Bergen , 5021, Norway
Oslo , 0424, Norway
Elblag , 82-30, Poland
Gdansk , 80-21, Poland
Krakow , 31-20, Poland
Lodz , 93-51, Poland
Poznan , 60-56, Poland
Warszawa , 02-78, Poland
Bucharest , 02012, Romania
Craiova , 20034, Romania
Romania , 40001, Romania
Timisoara, Timis , 30023, Romania
Moscow , 11547, Russian Federation
Ryazan , 39001, Russian Federation
Saint-Petersburg , 19775, Russian Federation
St. Petersburg , 19429, Russian Federation
Barcelona , 08025, Spain
Barcelona , 08035, Spain
Madrid , 28034, Spain
Madrid , 28050, Spain
Sevilla , 41009, Spain
Valencia , 46026, Spain
Basel , 4031, Switzerland
Lausanne , 1011, Switzerland
Winterthur , 8401, Switzerland
Zurich , 8091, Switzerland
Taichung , 404, Taiwan
London Greater London, SW3 6, United Kingdom
Manchester Greater Manchester, M20 4, United Kingdom
Maidstone Kent, ME16 , United Kingdom
Sutton Surrey, SM2 5, United Kingdom
Southampton , SO16 , United Kingdom
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