Lung Cancer Clinical Trial
Effectiveness Study of Nivolumab Compared to Chemotherapy in Patients With Relapsed Small-cell Lung Cancer
Summary
The purpose of this study is to compare the overall survival of nivolumab versus chemotherapy in subjects with relapsed SCLC.
View Eligibility Criteria
Eligibility Criteria
Inclusion Criteria:
Histologically or cytologically confirmed small cell lung cancer (SCLC)
Subjects with either limited or extensive disease stage at the initial diagnosis
Must have recurrence or progression after platinum-based first-line chemotherapy or chemoradiation therapy for the treatment of limited or extensive disease stage SCLC
Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
Exclusion Criteria:
Untreated or symptomatic central nervous system (CNS) metastases
Prior therapy with anti-PD-1, anti-PDL1, anti-PD-L2, anti-CD137, or anti-CTLA-4 antibody
Inadequate hematologic or hepatic function
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There are 145 Locations for this study
See Locations Near You
Univ Of Ark For Med Sci
Little Rock Arkansas, 72205, United States
Little Rock Arkansas, 72205, United States
Smilow Cancer Hospital. At Yale New Haven
New Haven Connecticut, 06520, United States
New Haven Connecticut, 06520, United States
Emory University
Atlanta Georgia, 30322, United States
Atlanta Georgia, 30322, United States
Washington University School Of Medicine
Saint Louis Missouri, 63110, United States
Saint Louis Missouri, 63110, United States
Nebraska Hematology Oncology Pc
Lincoln Nebraska, 68506, United States
Lincoln Nebraska, 68506, United States
Broome Oncology
Johnson City New York, 13790, United States
Johnson City New York, 13790, United States
Duke University
Durham North Carolina, 27710, United States
Durham North Carolina, 27710, United States
University Hospitals Cleveland Medical Center
Cleveland Ohio, 44106, United States
Cleveland Ohio, 44106, United States
St. Luke's University Health Network
Bethlehem Pennsylvania, 18015, United States
Bethlehem Pennsylvania, 18015, United States
Local Institution - 0057
Lancaster Pennsylvania, 17604, United States
Lancaster Pennsylvania, 17604, United States
Fox Chase Cancer Center
Philadelphia Pennsylvania, 19111, United States
Philadelphia Pennsylvania, 19111, United States
Tennessee Oncology, Pllc
Nashville Tennessee, 37203, United States
Nashville Tennessee, 37203, United States
Vanderbilt-Ingram Cancer Center
Nashville Tennessee, 37232, United States
Nashville Tennessee, 37232, United States
Kadlec Clinic Hematology and Oncology
Kennewick Washington, 99336, United States
Kennewick Washington, 99336, United States
Local Institution
Waratah New South Wales, 2298, Australia
Waratah New South Wales, 2298, Australia
Local Institution
Brisbane Queensland, 4032, Australia
Brisbane Queensland, 4032, Australia
Local Institution
Elizabeth Vale South Australia, 5112, Australia
Elizabeth Vale South Australia, 5112, Australia
Local Institution
Kurralta Park South Australia, 5037, Australia
Kurralta Park South Australia, 5037, Australia
Local Institution
Perth Western Australia, 6150, Australia
Perth Western Australia, 6150, Australia
Local Institution
Murdoch , 6150, Australia
Murdoch , 6150, Australia
Local Institution
Graz , 8036, Austria
Graz , 8036, Austria
Local Institution
Wels , 4600, Austria
Wels , 4600, Austria
Akh Wien
Wien , 1090, Austria
Wien , 1090, Austria
Local Institution
Bruxelles , 1200, Belgium
Bruxelles , 1200, Belgium
Local Institution
Edegem , 2650, Belgium
Edegem , 2650, Belgium
Local Institution
Leuven , 3000, Belgium
Leuven , 3000, Belgium
Local Institution - 0010
Yvoir , 5530, Belgium
Yvoir , 5530, Belgium
Local Institution - 0095
Ijui RIO Grande DO SUL, 98700, Brazil
Ijui RIO Grande DO SUL, 98700, Brazil
Local Institution
Porto Alegre Rio Grande Do Sul, 90610, Brazil
Porto Alegre Rio Grande Do Sul, 90610, Brazil
Local Institution
Barretos Sao Paulo, 14784, Brazil
Barretos Sao Paulo, 14784, Brazil
Local Institution
Sao Paulo , 01321, Brazil
Sao Paulo , 01321, Brazil
Local Institution
Recoleta Santiago De Chile, , Chile
Recoleta Santiago De Chile, , Chile
Local Institution
Beijing Beijing, 10000, China
Beijing Beijing, 10000, China
Local Institution
Beijing Beijing, 10002, China
Beijing Beijing, 10002, China
Local Institution
Beijing Beijing, 10003, China
Beijing Beijing, 10003, China
Local Institution
Beijing Beijing, 10114, China
Beijing Beijing, 10114, China
Local Institution
Guanzhou Guangdong, 51008, China
Guanzhou Guangdong, 51008, China
Local Institution
Zhengzhou Henan, 45000, China
Zhengzhou Henan, 45000, China
Local Institution
Nanjing Jiangsu, 21000, China
Nanjing Jiangsu, 21000, China
Local Institution
Changchun Jilin, 13001, China
Changchun Jilin, 13001, China
Local Institution
Xian Shaanxi, 71003, China
Xian Shaanxi, 71003, China
Local Institution - 0181
Shanghai Shanghai, 20002, China
Shanghai Shanghai, 20002, China
Local Institution
Shanghai Shanghai, 20003, China
Shanghai Shanghai, 20003, China
Local Institution
Urumqi Xinjiang, 83001, China
Urumqi Xinjiang, 83001, China
Local Institution - 0183
Hangzhou Zhejiang, 31002, China
Hangzhou Zhejiang, 31002, China
Local Institution
Beijing , 10007, China
Beijing , 10007, China
Local Institution
Guangzhou , , China
Guangzhou , , China
Local Institution
Hangzhou , 31001, China
Hangzhou , 31001, China
Local Institution
Shanghai , 20003, China
Shanghai , 20003, China
Local Institution
Brno , 625 0, Czechia
Brno , 625 0, Czechia
Klinika komplexni onkologicke pece
Brno , 656 5, Czechia
Brno , 656 5, Czechia
Klinika plicnich nemoci a tuberkulozy
Olomouc , 779 0, Czechia
Olomouc , 779 0, Czechia
Pneumologicka klinika 1. LF a TN
Praha 4 , 14059, Czechia
Praha 4 , 14059, Czechia
Local Institution - 0106
Copenhagen , 2100, Denmark
Copenhagen , 2100, Denmark
Local Institution - 0098
Herlev , 2730, Denmark
Herlev , 2730, Denmark
Local Institution - 0100
Odense , 5000, Denmark
Odense , 5000, Denmark
Chu Brest Hopital Morvan
Brest , 29200, France
Brest , 29200, France
CHRU Lille - Hopital Calmette
Lille Cedex , 59037, France
Lille Cedex , 59037, France
Hopital Cochin
Paris Cedex 14 , 75014, France
Paris Cedex 14 , 75014, France
Centre Hospitalier D'Annecy
Pringy Cedex , 74374, France
Pringy Cedex , 74374, France
Polyclinique De Courlancy
Reims , 51100, France
Reims , 51100, France
Hopital Sainte Musse
Toulon Cedex , 83056, France
Toulon Cedex , 83056, France
Local Institution
Bamberg , 96049, Germany
Bamberg , 96049, Germany
Local Institution
Berlin , 13125, Germany
Berlin , 13125, Germany
Local Institution
Essen , 45122, Germany
Essen , 45122, Germany
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Frankfurt am Main , 60590, Germany
Frankfurt am Main , 60590, Germany
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Gera , 07548, Germany
Gera , 07548, Germany
Local Institution
Gerlingen , 70839, Germany
Gerlingen , 70839, Germany
Local Institution
Grosshansdorf , 22927, Germany
Grosshansdorf , 22927, Germany
Local Institution
Halle (saale) , 06120, Germany
Halle (saale) , 06120, Germany
Local Institution
Hamburg , 21075, Germany
Hamburg , 21075, Germany
Local Institution
Heidelberg , 69126, Germany
Heidelberg , 69126, Germany
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Immenstadt , 87509, Germany
Immenstadt , 87509, Germany
Local Institution
Koeln , 50937, Germany
Koeln , 50937, Germany
Local Institution
Muenchen , 81925, Germany
Muenchen , 81925, Germany
Local Institution
Oberhausen , 46145, Germany
Oberhausen , 46145, Germany
Local Institution
Regensburg , 93053, Germany
Regensburg , 93053, Germany
University Hospital Of Heraklion
Heraklion Creta, 71110, Greece
Heraklion Creta, 71110, Greece
Sotiria General Hospital
Athens , 11527, Greece
Athens , 11527, Greece
Papageorgiou General Hospital
Thessaloniki , 56429, Greece
Thessaloniki , 56429, Greece
Pulmonologiai Klinika
Budapest , 1083, Hungary
Budapest , 1083, Hungary
Orsz.Koranyi Tbc es Pulm.Int.
Budapest , 1121, Hungary
Budapest , 1121, Hungary
Local Institution
Beer Sheva , 84101, Israel
Beer Sheva , 84101, Israel
Local Institution
Kfar Saba , , Israel
Kfar Saba , , Israel
Local Institution
Ramat -Gan , 52621, Israel
Ramat -Gan , 52621, Israel
Local Institution
Safed , 13100, Israel
Safed , 13100, Israel
Ospedale Bellaria-Maggiore
Bologna , 40139, Italy
Bologna , 40139, Italy
Local Institution - 0073
Livorno , 57100, Italy
Livorno , 57100, Italy
Ospedale San Luca
Lucca , 55100, Italy
Lucca , 55100, Italy
IRST Meldola
Meldola , 47014, Italy
Meldola , 47014, Italy
Local Institution
Milano , 20133, Italy
Milano , 20133, Italy
Azienda Ospedaliera - Nuovo Ospedale San Gerardo
Monza , 20052, Italy
Monza , 20052, Italy
Ospedale Degli Infermi
Rimini , 47923, Italy
Rimini , 47923, Italy
Azienda Ospedaliera S. Andrea
Roma , 00189, Italy
Roma , 00189, Italy
Local Institution
Nagoya-shi Aichi, 46486, Japan
Nagoya-shi Aichi, 46486, Japan
Local Institution
Nagoya Aichi, 460-0, Japan
Nagoya Aichi, 460-0, Japan
Local Institution - 0196
Kashiwa Chiba, 277-8, Japan
Kashiwa Chiba, 277-8, Japan
Local Institution
Matsuyama Ehime, 79102, Japan
Matsuyama Ehime, 79102, Japan
Local Institution
Fukuoka-shi Fukuoka, 811-1, Japan
Fukuoka-shi Fukuoka, 811-1, Japan
Local Institution
Akashi-shi Hyogo, 67385, Japan
Akashi-shi Hyogo, 67385, Japan
Local Institution
Kobe Hyogo, 65000, Japan
Kobe Hyogo, 65000, Japan
Local Institution
Natori-shi Miyagi, 98112, Japan
Natori-shi Miyagi, 98112, Japan
Local Institution - 0161
Niigata-shi Niigata, 951-8, Japan
Niigata-shi Niigata, 951-8, Japan
Local Institution
Habikino-shi Osaka, 58385, Japan
Habikino-shi Osaka, 58385, Japan
Local Institution
Hirakata-shi Osaka, 57311, Japan
Hirakata-shi Osaka, 57311, Japan
Local Institution
Osaka-sayama Osaka, 589-8, Japan
Osaka-sayama Osaka, 589-8, Japan
Local Institution - 0165
Osaka-shi Osaka, 53400, Japan
Osaka-shi Osaka, 53400, Japan
Local Institution
Sakai Osaka, 591-8, Japan
Sakai Osaka, 591-8, Japan
Local Institution
Kitaadachi-gun Saitama, 362-0, Japan
Kitaadachi-gun Saitama, 362-0, Japan
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Bunkyo-ku Tokyo, 11384, Japan
Bunkyo-ku Tokyo, 11384, Japan
Local Institution
Chuo-ku Tokyo, 10400, Japan
Chuo-ku Tokyo, 10400, Japan
Local Institution
Chuo-ku Tokyo, 54185, Japan
Chuo-ku Tokyo, 54185, Japan
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Wakayama-Shi Wakayama, 641-8, Japan
Wakayama-Shi Wakayama, 641-8, Japan
Local Institution - 0154
Tokyo , 135-8, Japan
Tokyo , 135-8, Japan
Local Institution
Suwon Gyeonggi-do, 16247, Korea, Republic of
Suwon Gyeonggi-do, 16247, Korea, Republic of
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Cheongju-si , 28644, Korea, Republic of
Cheongju-si , 28644, Korea, Republic of
Local Institution
Seoul , 02841, Korea, Republic of
Seoul , 02841, Korea, Republic of
Local Institution
Seoul , 05505, Korea, Republic of
Seoul , 05505, Korea, Republic of
Local Institution - 0096
Bergen , 5021, Norway
Bergen , 5021, Norway
Local Institution - 0072
Oslo , 0424, Norway
Oslo , 0424, Norway
Wojewodzki Szpital Zespolony W Elblagu
Elblag , 82-30, Poland
Elblag , 82-30, Poland
Klinika Onkologii I Radioterapii Am
Gdansk , 80-21, Poland
Gdansk , 80-21, Poland
Oddzial Onkologiczny
Krakow , 31-20, Poland
Krakow , 31-20, Poland
Regionalny Osrodek Onkologiczny
Lodz , 93-51, Poland
Lodz , 93-51, Poland
Oddzial Onkologii Klinicznej
Poznan , 60-56, Poland
Poznan , 60-56, Poland
Klinika Nowotworow Pluca i Klatki Piersiowej
Warszawa , 02-78, Poland
Warszawa , 02-78, Poland
Local Institution
Bucharest , 02012, Romania
Bucharest , 02012, Romania
Local Institution
Craiova , 20034, Romania
Craiova , 20034, Romania
Local Institution - 0113
Romania , 40001, Romania
Romania , 40001, Romania
Local Institution
Timisoara, Timis , 30023, Romania
Timisoara, Timis , 30023, Romania
Local Institution
Moscow , 11547, Russian Federation
Moscow , 11547, Russian Federation
Local Institution
Ryazan , 39001, Russian Federation
Ryazan , 39001, Russian Federation
Local Institution
Saint-Petersburg , 19775, Russian Federation
Saint-Petersburg , 19775, Russian Federation
Local Institution
St. Petersburg , 19429, Russian Federation
St. Petersburg , 19429, Russian Federation
Local Institution
Barcelona , 08025, Spain
Barcelona , 08025, Spain
Local Institution
Barcelona , 08035, Spain
Barcelona , 08035, Spain
Local Institution
Madrid , 28034, Spain
Madrid , 28034, Spain
Local Institution
Madrid , 28050, Spain
Madrid , 28050, Spain
Local Institution - 0008
Sevilla , 41009, Spain
Sevilla , 41009, Spain
Local Institution - 0007
Valencia , 46026, Spain
Valencia , 46026, Spain
Local Institution
Basel , 4031, Switzerland
Basel , 4031, Switzerland
Centre hospitalier universitaire Vaudois (CHUV)
Lausanne , 1011, Switzerland
Lausanne , 1011, Switzerland
Local Institution
Winterthur , 8401, Switzerland
Winterthur , 8401, Switzerland
Local Institution
Zurich , 8091, Switzerland
Zurich , 8091, Switzerland
Local Institution
Taichung , 404, Taiwan
Taichung , 404, Taiwan
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London Greater London, SW3 6, United Kingdom
London Greater London, SW3 6, United Kingdom
Local Institution
Manchester Greater Manchester, M20 4, United Kingdom
Manchester Greater Manchester, M20 4, United Kingdom
Local Institution
Maidstone Kent, ME16 , United Kingdom
Maidstone Kent, ME16 , United Kingdom
Local Institution
Sutton Surrey, SM2 5, United Kingdom
Sutton Surrey, SM2 5, United Kingdom
Local Institution
Southampton , SO16 , United Kingdom
Southampton , SO16 , United Kingdom
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