Lung Cancer Clinical Trial
Lung Cancer Screening Study With Low-dose CT Scan and Blood Biomarker
Lung cancer is the number one cancer killer in the USA. Early stage lung cancer is asymptomatic. Most patients with lung cancer are usually symptomatic at diagnosis and already have advanced stage disease. Low dose CT screening (LDCT) for high risk individuals has recently been shown to decrease lung cancer mortality by 20%. However, 4 out of 5 lung cancer deaths are not prevented with LDCT screening alone.
In this trial, the addition of a blood biomarker test is being combined with early LDCT to determine if screening with combination may result in detection of more lung cancer at an earlier stage of disease.The study will also assess if the blood test is able to detect lung cancers in high risk individuals when the LDCT is negative for cancer. There will be health-economic costs included in the final analysis of study data.
Smokers or former smokers
At least 20 pack year history of smoking
Ages 50 - 75
Had a CT scan of chest within last 24 months
History of any cancer within 10 yrs (except skin cancer or cervical cancer)
A serious illness that decreases life expectancy to less than 5 years
Any current use of Oxygen
Uncontrolled congestive heart failure or cardiac arrhythmia that would prevent surgery for a lung lesion
Severe COPD or dyspnea that would prevent lung surgery or stereotactic body radiotherapy
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There is 1 Location for this study
Denver Colorado, 80206, United States
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