Lung Cancer Clinical Trial

Metabolic and Microbial Profiling of Lung Cancer

Summary

This pilot study will establish non-invasive sample collections, including breath, saliva, blood and urine pre-surgery and at the participant's one-month post-surgery follow-up visit. Participants with suspected non-small cell lung cancer (NSCLC) stage I-III will be recruited.

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Full Description

Primary Objective

To evaluate the feasibility of adding non-invasive sample collections in the pre-surgical setting and at the post-surgery follow-up visit.
To identify and assess metabolic and microbial signatures collected at pre- and post-surgery and determine which are indicative of lung cancer.

Secondary Objective

To identify signatures which are associated with lung cancer stage.
To identify signatures which are impacted by patient's pulmonary function status.

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Eligibility Criteria

Inclusion Criteria:

Male and female patients age >18 years, of all racial and ethnic origins, with suspected nonsmall cell lung cancer stages I, II, and III, as evident through radiographic evidence and felt acceptable to undergo surgical resection.
Patients who have the ability to understand and the willingness to sign a written consent form.

Exclusion Criteria:

Patients who are have taken antibiotics within two weeks.
Patients who are on continuous supplemental oxygen.
Patients currently undergoing active treatment for other malignancies.
Subjects who are unable or unwilling to provide consent.

Study is for people with:

Lung Cancer

Estimated Enrollment:

1

Study ID:

NCT03998189

Recruitment Status:

Terminated

Sponsor:

Wake Forest University Health Sciences

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There is 1 Location for this study

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Wake Forest Baptist Comprehensive Cancer Center
Winston-Salem North Carolina, 27157, United States

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Estimated Enrollment:

1

Study ID:

NCT03998189

Recruitment Status:

Terminated

Sponsor:


Wake Forest University Health Sciences

How clear is this clinincal trial information?

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