Lung Cancer Clinical Trial

Pathways, a Hope Intervention to Support Personal Goal Pursuit, Mental Health, and Quality of Life During Advanced Lung Cancer Treatment

Summary

This study will compare the effects of a brief supportive intervention, called Pathways, against enhanced usual care on the mental health and quality of life of people undergoing treatment for advanced lung cancer. Patients will complete baseline survey measures and be randomized to intervention. Survey measures will be collected again mid-intervention, post-intervention and at 6- and 12-week follow-up, with analyses focused on changes pre- to post-intervention.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

New or recurrent AJCC 8th edition stage 3b, 3c, or IV non-small cell lung cancer, extensive stage small cell lung cancer
18 years of age or older
Eastern Cooperative Oncology Group (ECOG) performance status 0-2/Karnofsky 60-100
3-12 weeks into systemic, infusion-based treatment (chemotherapy, immunotherapy, chemo-immunotherapy)
Past month distress score (per electronic health record) of 3/10 or higher OR a Rotterdam Symptom item score of 2 or higher for psychological distress items.

Exclusion Criteria:

Unstable brain metastases (i.e., progressive neurological deficits, inadequately controlled seizures, or requiring escalated steroid doses)
Cognitive (i.e., dementia) or psychiatric condition (e.g., psychotic disorder) for which participating would be inappropriate
Receiving overlapping palliative care or psychological services at the cancer center
Unable to speak and read English.

Study is for people with:

Lung Cancer

Estimated Enrollment:

234

Study ID:

NCT06047301

Recruitment Status:

Not yet recruiting

Sponsor:

Laurie McLouth

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There is 1 Location for this study

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University of Kentucky
Lexington Kentucky, 40506, United States More Info
Laurie McLouth, PhD
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How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Estimated Enrollment:

234

Study ID:

NCT06047301

Recruitment Status:

Not yet recruiting

Sponsor:


Laurie McLouth

How clear is this clinincal trial information?

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