Lung Cancer Clinical Trial

Safety and Efficacy Study of Ulocuplumab and Nivolumab in Subjects With Solid Tumors

Summary

The purpose of this study is to determine whether the combination of Ulocuplumab and Nivolumab is safe and effective in the treatment of pancreatic cancer and small cell lung cancer.

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Full Description

Intervention model: Single group for Stage 1 DLT, then Parallel
Data Monitoring Committee: No (Stage 1) Yes (Stage 2 Randomized Ph2)

View Eligibility Criteria

Eligibility Criteria

For more information regarding BMS clinical trial participation, please visit www.BMSStudyConnect.com

Inclusion Criteria:

SCLC or PAC that is advanced or has spread to other parts of the body
Treated with at least one other chemotherapy that did not work or where cancer relapsed
Minimal limitations on activities of daily living as measured by Eastern Cooperative Oncology Group (ECOG) score of 0-1

Exclusion Criteria:

Patients with cancer that spread to the brain
Active, known or suspected autoimmune disease
Prior treatment with any drug that targets T cell co-stimulation pathways (such as checkpoint inhibitors)

Study is for people with:

Lung Cancer

Phase:

Phase 1

Estimated Enrollment:

61

Study ID:

NCT02472977

Recruitment Status:

Terminated

Sponsor:

Bristol-Myers Squibb

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There are 7 Locations for this study

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University Of Colorado Hosp
Aurora Colorado, 80045, United States
Indiana University Health
Indianapolis Indiana, 46202, United States
Sidney Kimmel Comprehensive Cancer Center At Johns Hopkins
Baltimore Maryland, 21287, United States
Columbia University Medical Center (Cumc)
New York New York, 10032, United States
Memorial Sloan Kettering Cancer Center
New York New York, 10065, United States
Huntsman Cancer Institute
Salt Lake City Utah, 84112, United States
Local Institution
Helsinki , 00029, Finland

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 1

Estimated Enrollment:

61

Study ID:

NCT02472977

Recruitment Status:

Terminated

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

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