Lung Cancer Clinical Trial

Study of TRM-1(TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-Small Cell Lung Cancer (NSCLC)

Summary

The purpose of this study is to evaluate the efficacy and safety of TRM-1 in subjects with relapsed or refractory non-small cell lung cancer.

View Eligibility Criteria

Eligibility Criteria

Primary Inclusion Criteria:

Relapsed or refractory histologically or cytologically confirmed Stage IIIB, IV, or recurrent NSCLC
Previously treated and failed to respond to standard therapy or progressed after standard therapy
18 years of age or older

Primary Exclusion Criteria:

Received a non-FDA approved investigational agent within the last 4 weeks.
Previous cancer therapies (chemotherapy, hormonal therapy, monoclonal antibodies or radiation therapy) within the last 3 weeks, 8 weeks for fully human or humanized monoclonal antibodies
Infection requiring antibiotics or hospitalization within the last 2 weeks
HIV, Hepatitis-B, Hepatitis-C
Pregnant or breast-feeding women
Major surgery within the last 4 weeks
History of other cancers within the past 5 years

Study is for people with:

Lung Cancer

Phase:

Phase 2

Study ID:

NCT00092924

Recruitment Status:

Completed

Sponsor:

Human Genome Sciences Inc.

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There are 5 Locations for this study

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University of Colorado Cancer Center
Denver Colorado, 80220, United States
Rush Medical College
Chicago Illinois, 60612, United States
Duke Comprehensive Cancer Center
Durham North Carolina, 27710, United States
Sarah Cannon Cancer Center
Nashville Tennessee, 37203, United States
MD Anderson
Houston Texas, 77230, United States

How clear is this clinincal trial information?

Study is for people with:

Lung Cancer

Phase:

Phase 2

Study ID:

NCT00092924

Recruitment Status:

Completed

Sponsor:


Human Genome Sciences Inc.

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