Melanoma Clinical Trial

A Study of Belzutifan (MK-6482) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Clear Cell Renal Cell Carcinoma Post Nephrectomy (MK-6482-022)

Summary

The purpose of this study is to assess the efficacy and safety of oral belzutifan (MK-6482) plus intravenous (IV) pembrolizumab (MK-3475) compared to placebo plus pembrolizumab, in the adjuvant treatment of Clear Cell Renal Cell Carcinoma (ccRCC) post nephrectomy.

The primary study hypothesis is that belzutifan plus pembrolizumab is superior to placebo plus pembrolizumab with respect to disease-free survival (DFS).

View Eligibility Criteria

Eligibility Criteria

The main inclusion and exclusion criteria include but are not limited to the following:

Inclusion Criteria:

Has a histologically or cytologically confirmed diagnosis of RCC with clear cell component per American Joint Committee on Cancer (AJCC) (8th Edition), with or without sarcomatoid features

Has intermediate-high risk, high risk, or M1 no evidence of disease (NED) RCC as defined by the following pathological tumor-node metastasis and tumor grading:

Intermediate-high risk RCC: pT2, Grade 4 or sarcomatoid, N0, M0; pT3, any grade, N0, M0
High risk RCC: pT4, any Grade N0, M0; pT any stage, any Grade, N+, M0
M1 NED RCC participants who present not only with the primary kidney tumor but also solid, isolated, soft tissue metastases that can be completely resected at one of the following: the time of nephrectomy (synchronous) or, ≤2 years from nephrectomy (metachronous)
Has undergone complete resection of the primary tumor (partial or radical nephrectomy) and complete resection of solid, isolated, soft tissue metastatic lesion(s) in M1 NED participants
Must have undergone a nephrectomy and/or metastasectomy ≤12 weeks prior to randomization
Has Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 1 within 10 days before randomization.
Male participants must agree to continue contraception at least 7 days after the last dose of belzutifan/placebo
Female participants of childbearing potential must be willing to use an adequate method of contraception, for the course of the study through 120 days after the last dose of pembrolizumab or at least 30 days after last dose of belzutifan/placebo, whichever occurs last
Has adequate organ function

Exclusion Criteria:

Has had a major surgery, other than nephrectomy plus resection of preexisting metastases for M1 NED participants, within 4 weeks prior to randomization
Has a pulse oximeter reading <92% at rest, requires intermittent supplemental oxygen, or requires chronic supplemental oxygen
Has clinically significant cardiovascular disease within 6 months from first dose of study intervention
Has other clinically significant disorders such as: serious active nonhealing wound/ulcer/bone fracture; requirement for hemodialysis or peritoneal dialysis
Has preexisting brain or bone metastatic lesions
Has received prior systemic therapy for RCC
Has received prior radiotherapy for RCC
Has received a live or live-attenuated vaccine within 30 days before the first dose of study intervention; administration of killed vaccines are allowed
Has a diagnosis of immunodeficiency or is receiving chronic systemic steroid therapy
Has a known additional malignancy (other than RCC treated with nephrectomy and/or metastasectomy) that is progressing or has required active treatment within the past 3 years
Has an active autoimmune disease that has required systemic treatment in past 2 years (i.e., with use of disease modifying agents, corticosteroids, or immunosuppressive drugs); replacement therapy is allowed
Has a history of (noninfectious) pneumonitis/interstitial lung disease that required steroids or has current pneumonitis/interstitial lung disease
Has an active infection, requiring systemic therapy
Has a known history of human immunodeficiency virus (HIV) infection, a known history of Hepatitis B or known active Hepatitis C virus infection
Has had an allogenic tissue/solid organ transplant

Study is for people with:

Melanoma

Phase:

Phase 3

Estimated Enrollment:

1600

Study ID:

NCT05239728

Recruitment Status:

Recruiting

Sponsor:

Merck Sharp & Dohme LLC

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There are 227 Locations for this study

See Locations Near You

City of Hope Comprehensive Cancer Center ( Site 3567)
Duarte California, 91010, United States More Info
Study Coordinator
Contact
626256467389200
Stanford Cancer Center ( Site 3523)
Palo Alto California, 94304, United States More Info
Study Coordinator
Contact
650-725-2078
University of Colorado Anschutz Medical Campus ( Site 3514)
Aurora Colorado, 80045, United States More Info
Study Coordinator
Contact
720-848-3427
St. Mary's Hospital and Regional Medical Center-SCL Health Cancer Centers of Colorado-St. Mary's ( S
Grand Junction Colorado, 81501, United States More Info
Study Coordinator
Contact
970-298-7500
Georgetown University Medical Center ( Site 3534)
Washington District of Columbia, 20007, United States More Info
Study Coordinator
Contact
202-687-6957
University of Miami Hospital and Clinics, Sylvester Cancer Center-Cancer Research Services ( Site 35
Miami Florida, 33136, United States More Info
Study Coordinator
Contact
954-243-1000
Northwest Georgia Oncology Centers, a Service of Wellstar Cobb Hospital-Research ( Site 3515)
Marietta Georgia, 30060, United States More Info
Study Coordinator
Contact
770-281-5101
Parkview Research Center at Parkview Regional Medical Center ( Site 3526)
Fort Wayne Indiana, 46845, United States More Info
Study Coordinator
Contact
260-425-6800
Johns Hopkins Hospital-Sidney Kimmel Comprehensive Cancer Center- GU Oncology ( Site 3549)
Baltimore Maryland, 21231, United States More Info
Study Coordinator
Contact
410-570-9410
Dana-Farber Cancer Institute-GU ( Site 3505)
Boston Massachusetts, 02215, United States More Info
Study Coordinator
Contact
617-632-5456
Cancer and Hematology Centers of Western Michigan ( Site 3502)
Grand Rapids Michigan, 49503, United States More Info
Study Coordinator
Contact
269-993-6056
Washington University-Internal Medicine/Oncology ( Site 3531)
Saint Louis Missouri, 63110, United States More Info
Study Coordinator
Contact
314-362-5740
St. Vincent Frontier Cancer Center-Research ( Site 3506)
Billings Montana, 59102, United States More Info
Study Coordinator
Contact
406-238-6290
Oncology Hematology West, PC dba Nebraska Cancer Specialists ( Site 3550)
Omaha Nebraska, 68130, United States More Info
Study Coordinator
Contact
402-334-4773
Englewood Hospital and Medical Center ( Site 3557)
Englewood New Jersey, 07631, United States More Info
Study Coordinator
Contact
201-568-5250
Rutgers Cancer Institute of New Jersey ( Site 3541)
New Brunswick New Jersey, 08903, United States More Info
Study Coordinator
Contact
732-235-2465
Monter Cancer Center ( Site 3560)
Lake Success New York, 11042, United States More Info
Study Coordinator
Contact
516-734-8894
Icahn School of Medicine at Mount Sinai ( Site 3539)
New York New York, 10029, United States More Info
Study Coordinator
Contact
212-824-8782
Memorial Sloan Kettering Cancer Center ( Site 3568)
New York New York, 10065, United States More Info
Study Coordinator
Contact
646-422-4312
The James Cancer Hospital and Solove Research Institute at The Ohio State University Comprehensive C
Columbus Ohio, 43210, United States More Info
Study Coordinator
Contact
614-293-1870
MidLantic urology ( Site 3501)
Bala-Cynwyd Pennsylvania, 19004, United States More Info
Study Coordinator
Contact
610-667-0458
Fox Chase Cancer Center-GU Oncology ( Site 3535)
Philadelphia Pennsylvania, 19111, United States More Info
Study Coordinator
Contact
215-728-4300
Sanford Cancer Center ( Site 3551)
Sioux Falls South Dakota, 57104, United States More Info
Study Coordinator
Contact
605-328-8000
The West Clinic, PLLC dba West Cancer Center ( Site 3522)
Germantown Tennessee, 38138, United States More Info
Study Coordinator
Contact
901-683-0055
Urology Associates ( Site 3512)
Nashville Tennessee, 37209, United States More Info
Study Coordinator
Contact
615-250-9200
UT Southwestern Medical Center ( Site 3529)
Dallas Texas, 75390, United States More Info
Study Coordinator
Contact
301-512-7242
University of Texas MD Anderson Cancer Center-Urology ( Site 3569)
Houston Texas, 77030, United States More Info
Study Coordinator
Contact
713-792-3250
Inova Schar Cancer Institute ( Site 3525)
Fairfax Virginia, 22031, United States More Info
Study Coordinator
Contact
267-240-2756
Seattle Cancer Care Alliance-Renal/Melanoma/MCC ( Site 3524)
Seattle Washington, 98109, United States More Info
Study Coordinator
Contact
425-830-1098
Blacktown Hospital-Blacktown Cancer and Haematology Centre - Medical Oncology ( Site 0002)
Blacktown New South Wales, 2148, Australia More Info
Study Coordinator
Contact
0286705077
Macquarie University-MQ Health Clinical Trials Unit ( Site 0003)
Macquarie University New South Wales, 2109, Australia More Info
Study Coordinator
Contact
+61298122956
Tamworth Hospital-North West Cancer Centre ( Site 0006)
North Tamworth New South Wales, 2340, Australia More Info
Study Coordinator
Contact
+61 2 6767 7760
Royal Brisbane and Women's Hospital-Medical Oncology Clinical Trials Unit, Cancer Care Services ( Si
Brisbane Queensland, 4029, Australia More Info
Study Coordinator
Contact
+61736467983
Lyell McEwin Hospital-Oncology Clinical Trials Unit ( Site 0008)
Elizabeth Vale South Australia, 5112, Australia More Info
Study Coordinator
Contact
61882820833
Austin Health-Cancer Clinical Trials Centre ( Site 0005)
Heidelberg Victoria, 3084, Australia More Info
Study Coordinator
Contact
+6139493352
Fiona Stanley Hospital-Medical Oncology ( Site 0004)
Murdoch Western Australia, 6150, Australia More Info
Study Coordinator
Contact
61861526530
Hospital São Carlos-Oncocentro Ce ( Site 0104)
Fortaleza Ceara, 60135, Brazil More Info
Study Coordinator
Contact
55 85 991122944
Centro Avançado de Tratamento Oncológico- CENANTRON-Clinical Research ( Site 0105)
Belo Horizonte Minas Gerais, 30130, Brazil More Info
Study Coordinator
Contact
55 31 993092597
Instituto do Câncer e Transplante de Curitiba ( Site 0102)
Curitiba Parana, 80510, Brazil More Info
Study Coordinator
Contact
55 41 992057755
Liga Norte Riograndense Contra o Câncer-Centro de Pesquisa Clínica ( Site 0103)
Natal Rio Grande Do Norte, 59075, Brazil More Info
Study Coordinator
Contact
+558440095595
Hospital Nossa Senhora da Conceição-Centro Integrado de Pesquisa em Oncologia ( Site 0101)
Porto Alegre Rio Grande Do Sul, 91350, Brazil More Info
Study Coordinator
Contact
+55 51 33572092
Hospital de Clínicas de Ribeirão Preto ( Site 0112)
Ribeirão Preto Sao Paulo, 14048, Brazil More Info
Study Coordinator
Contact
+551699174
BP - A Beneficencia Portuguesa de São Paulo ( Site 0111)
Sao Paulo , 01321, Brazil More Info
Study Coordinator
Contact
+551135056541
MBAL Uni Hospital-Department of Medical Oncology ( Site 0204)
Panagyurishte Pazardzhik, 4500, Bulgaria More Info
Study Coordinator
Contact
+35935788546
MHAT Serdika-Second Department of Medical Oncology ( Site 0203)
Sofia Sofia (stolitsa), 1301, Bulgaria More Info
Study Coordinator
Contact
+35929049100
BC Cancer Vancouver-Clinical Trials Unit ( Site 3707)
Vancouver British Columbia, V5Z 4, Canada More Info
Study Coordinator
Contact
6048776000
Victoria Hospital & Children's Hospital - London Health Scie-London Regional Cancer Program ( Site 3
London Ontario, N6A 5, Canada More Info
Study Coordinator
Contact
519-685-8500
McGill University Health Centre ( Site 3709)
Montréal Quebec, H4A 3, Canada More Info
Study Coordinator
Contact
5149341934
Centre intégré de cancérologie du CHU de Québec Université Laval, Hôpital de l'Enfant-Jésus ( Site 3
Quebec City Quebec, G1J 1, Canada More Info
Study Coordinator
Contact
418-525-4444
James Lind Centro de Investigación del Cáncer ( Site 0307)
Temuco Araucania, 48008, Chile More Info
Study Coordinator
Contact
+56 9 7431 6500
Clínica Puerto Montt ( Site 0309)
Puerto Montt Los Lagos, 55002, Chile More Info
Study Coordinator
Contact
+56 9 9863 4501
Oncocentro Valdivia ( Site 0312)
Valdivia Los Rios, 50900, Chile More Info
Study Coordinator
Contact
+56992195434
FALP-UIDO ( Site 0302)
Santiago Region M. De Santiago, 69009, Chile More Info
Study Coordinator
Contact
56224218596
Oncovida ( Site 0306)
Santiago Region M. De Santiago, 75100, Chile More Info
Study Coordinator
Contact
+56972151681
Bradfordhill ( Site 0305)
Santiago Region M. De Santiago, 84203, Chile More Info
Study Coordinator
Contact
+56229490970
ONCOCENTRO APYS-ACEREY ( Site 0301)
Viña del Mar Valparaiso, 25205, Chile More Info
Study Coordinator
Contact
+56323320850
Centro de Investigación Oncológica del Norte ( Site 0303)
Antofagasta , 12400, Chile More Info
Study Coordinator
Contact
+56 9 9419 8125
Afflilated Hospital of Bengbu Medical College-Urology Surgery ( Site 0438)
Bengbu Anhui, 23300, China More Info
Study Coordinator
Contact
13955259747
Second Affiliated hospital of Anhui Medical University-Urology ( Site 0416)
Hefei Anhui, 23000, China More Info
Study Coordinator
Contact
+8613705690883
Peking University First Hospital-Urology ( Site 0407)
Beijing Beijing, 10003, China More Info
Study Coordinator
Contact
8613910688432
Beijing Cancer hospital-Urinary Surgery ( Site 0406)
Beijing Beijing, 10014, China More Info
Study Coordinator
Contact
+86-10-88196023
Chinese PLA General Hospital ( Site 0415)
Beijing Beijing, 10085, China More Info
Study Coordinator
Contact
861068182255
Chongqing University Cancer Hospital ( Site 0414)
Chongqing Chongqing, 40003, China More Info
Study Coordinator
Contact
13883029913
SUN YAT-SEN UNIVERSITY CANCER CENTRE-Urology Surgery ( Site 0417)
Guangzhou Guangdong, 51006, China More Info
Study Coordinator
Contact
13822735659
Sun Yat-sen Memorial Hospital, Sun Yat-sen University-Urology Surgery ( Site 0402)
Guangzhou Guangdong, 51012, China More Info
Study Coordinator
Contact
+8613600054833
The First Affiliated Hospital of Guangzhou Medical University-Urology ( Site 0403)
Guangzhou Guangdong, 51012, China More Info
Study Coordinator
Contact
13719007083
Wuhan Union Hospital ( Site 0430)
Wuhan Hubei, 43002, China More Info
Study Coordinator
Contact
18602752025
Tongji Hospital Tongji Medical,Science & Technology-oncology ( Site 0423)
Wuhan Hubei, 43003, China More Info
Study Coordinator
Contact
13367255851
Hubei Cancer Hospital-Urinary surgery ( Site 0419)
Wuhan Hubei, 43007, China More Info
Study Coordinator
Contact
13907110640
Hunan Cancer Hospital ( Site 0421)
Changsha Hunan, 41001, China More Info
Study Coordinator
Contact
8673189762510
Nanjing Drum Tower Hospital The Affiliated Hospital of Nanjing University Medical School-Urology ( S
Nanjing Jiangsu, 21000, China More Info
Study Coordinator
Contact
+8613605171690
The First Affiliated Hospital of Nanchang University ( Site 0432)
Nanchang Jiangxi, 33000, China More Info
Study Coordinator
Contact
8618279116868
The First Affiliated Hospital of Xi'an Jiaotong University ( Site 0431)
Xi'an Shaanxi, 71006, China More Info
Study Coordinator
Contact
+029 85323473
Fudan University Shanghai Cancer Center-Urology department ( Site 0401)
Shanghai Shanghai, 20003, China More Info
Study Coordinator
Contact
+8613701663571
Huadong Hospital Affiliated to Fudan University ( Site 0405)
Shanghai Shanghai, 20004, China More Info
Study Coordinator
Contact
13301807126
West China Hospital of Sichuan University-Urology Surgery ( Site 0410)
Cheng Du Sichuan, 61004, China More Info
Study Coordinator
Contact
13881749152
Tianjin Medical University Cancer Institute and Hospital ( Site 0422)
Tianjin Tianjin, 30006, China More Info
Study Coordinator
Contact
+86 (022) 23340123-6416
The First Affiliated Hospital, Zhejiang University ( Site 0428)
Hangzhou Zhejiang, 31000, China More Info
Study Coordinator
Contact
13957120101
Zhejiang Provincial People's Hospital-Urology ( Site 0426)
Hangzhou Zhejiang, 31001, China More Info
Study Coordinator
Contact
+8613958036776
Ningbo First Hospital-Urology ( Site 0433)
Ningbo Zhejiang, 31501, China More Info
Study Coordinator
Contact
13967897956
The First Affiliated Hospital of Wenzhou Medical University-Urology Surgery ( Site 0425)
Wenzhou Zhejiang, 32500, China More Info
Study Coordinator
Contact
+8613626582653
Clinica de la Costa S.A.S. ( Site 0506)
Barranquilla Atlantico, 08002, Colombia More Info
Study Coordinator
Contact
+573008457696
Sociedad De Oncologia Y Hematologia Del Cesar-Oncology ( Site 0505)
Valledupar Cesar, 20000, Colombia More Info
Study Coordinator
Contact
+573128385292
Oncomedica S.A. ( Site 0501)
Monteria Cordoba, 23000, Colombia More Info
Study Coordinator
Contact
+573105394868
Administradora Country S.A. - Clinica del Country ( Site 0504)
Bogotá Distrito Capital De Bogota, 11022, Colombia More Info
Study Coordinator
Contact
+ 57 3108627483
Masarykuv onkologicky ustav-Klinika komplexni onkologicke pece ( Site 0605)
Brno Brno-mesto, 656 5, Czechia More Info
Study Coordinator
Contact
+420543136226
Fakultni Nemocnice u sv. Anny v Brne-Onkologicko-chirurgicke oddeleni ( Site 0603)
Brno Brno-mesto, 656 9, Czechia More Info
Study Coordinator
Contact
+420543183088
Fakultni nemocnice Ostrava-Klinika onkologicka ( Site 0606)
Ostrava Moravskoslezsky Kraj, 708 5, Czechia More Info
Study Coordinator
Contact
+420597372111
Fakultni nemocnice Olomouc-Onkologicka klinika ( Site 0601)
Olomouc Olomoucky Kraj, 779 0, Czechia More Info
Study Coordinator
Contact
+420588444295
Fakultni Thomayerova nemocnice-Onkologicka klinika 1. LF UK ( Site 0602)
Prague Praha 4, 140 5, Czechia More Info
Study Coordinator
Contact
+420261083530
Fakultni nemocnice Hradec Kralove-Klinika onkologie a radioterapie ( Site 0604)
Hradec Kralove , 500 0, Czechia More Info
Study Coordinator
Contact
+420727854666
Tampereen yliopistollinen sairaala ( Site 0805)
Tampere Pirkanmaa, 33520, Finland More Info
Study Coordinator
Contact
+358 3 31163082
Oulun yliopistollinen sairaala ( Site 0802)
Oulu Pohjois-Pohjanmaa, 90220, Finland More Info
Study Coordinator
Contact
+35883152870
Helsinki University Hospital - Comprehensive Cancer Center (HYKS - Syöpäkeskus) ( Site 0803)
Helsinki Uusimaa, 00290, Finland More Info
Study Coordinator
Contact
+358504279697
Turku University Hospital ( Site 0801)
Turku Varsinais-Suomi, 20520, Finland More Info
Study Coordinator
Contact
+35823130729
Institut de cancérologie Strasbourg Europe (ICANS) ( Site 0903)
Strasbourg Alsace, 67033, France More Info
Study Coordinator
Contact
0368767359
ROC37 ( Site 0910)
Chambray Les Tours Centre, 37170, France More Info
Study Coordinator
Contact
0247602574
CHU Besançon-Medical oncology ( Site 0904)
Besançon Doubs, 25000, France More Info
Study Coordinator
Contact
0033(0)370632005
Gustave Roussy ( Site 0907)
Villejuif Ile-de-France, 94800, France More Info
Study Coordinator
Contact
+33142115026
Centre Hospitalier Universitaire de Rennes - Hôpital Pontchaillou ( Site 0908)
Rennes Ille-et-Vilaine, 35000, France More Info
Study Coordinator
Contact
02 99 28 42 70
Centre Hospitalier Universitaire d'Angers-Urology ( Site 0901)
Angers Maine-et-Loire, 49933, France More Info
Study Coordinator
Contact
02 41 35 36 37
CENTRE LEON BERARD-Medical oncology ( Site 0902)
Lyon Rhone-Alpes, 69008, France More Info
Study Coordinator
Contact
+ 33 4 26 55 67 59
Hôpital Saint-Louis ( Site 0905)
Paris , 75010, France More Info
Study Coordinator
Contact
+33142494949
Hôpital Européen Georges Pompidou-Service d'Oncologie Médicale ( Site 0906)
Paris , 75015, France More Info
Study Coordinator
Contact
+33156092431
Universitaetsklinikum Tuebingen ( Site 1002)
Tübingen Baden-Wurttemberg, 72076, Germany More Info
Study Coordinator
Contact
4970712987235
klinikum rechts der isar der technischen universität münchen-Urologische Klinik und Poliklinik ( Sit
Munich Bayern, 81675, Germany More Info
Study Coordinator
Contact
498941402576
Universitätsklinikum Bonn ( Site 1006)
Bonn Nordrhein-Westfalen, 53127, Germany More Info
Study Coordinator
Contact
+49 228 287 16202
Universitaetsklinikum Duesseldorf ( Site 1017)
Düsseldorf Nordrhein-Westfalen, 40225, Germany More Info
Study Coordinator
Contact
+49 211 8118110
Universitaetsklinikum Essen ( Site 1004)
Essen Nordrhein-Westfalen, 45122, Germany More Info
Study Coordinator
Contact
+49 201 723 3213
Universitätsklinikum Münster - Albert Schweitzer Campus ( Site 1005)
Münster Nordrhein-Westfalen, 48149, Germany More Info
Study Coordinator
Contact
+49 (0) 251 8347446
Universitaetsklinikum des Saarlandes-Klinik fuer Urologie und Kinderurologies ( Site 1020)
Homburg Saarland, 66421, Germany More Info
Study Coordinator
Contact
4968411624787
Universitaetsklinikum Carl Gustav Carus Dresden-Klinik und Poliklinik für Urologie ( Site 1021)
Dresden Sachsen, 01307, Germany More Info
Study Coordinator
Contact
+49 351 458 4425
SRH Wald-Klinikum Gera ( Site 1015)
Gera Thuringen, 07548, Germany More Info
Study Coordinator
Contact
+49-(0)365 828 - 7151
Universitätsklinikum Jena ( Site 1007)
Jena Thuringen, 07747, Germany More Info
Study Coordinator
Contact
+49 3641 9 32 9947
Helios Klinikum Berlin-Buch ( Site 1011)
Berlin , 13125, Germany More Info
Study Coordinator
Contact
4930940154801
Universitaetsklinikum Hamburg-Eppendorf-Onkologisches Zentrum ( Site 1001)
Hamburg , 20246, Germany More Info
Study Coordinator
Contact
+49 (0) 40 7410-57118
Alexandra Hospital-ONCOLOGY DEPT. ( Site 1102)
Athens Attiki, 115 2, Greece More Info
Study Coordinator
Contact
0302132162513
Metropolitan Hospital-2nd Oncology Dept ( Site 1104)
Athens Attiki, 185 4, Greece More Info
Study Coordinator
Contact
+302104809150
ATTIKON GENERAL UNIVERSITY HOSPITAL ( Site 1101)
Chaidari Attiki, 124 6, Greece More Info
Study Coordinator
Contact
+302105831255
Euromedica General Clinic Thessaloniki-Oncology Unit ( Site 1103)
Thessaloniki , 546 4, Greece More Info
Study Coordinator
Contact
0302313252011
Szegedi Tudományegyetem Szent-Györgyi Albert Klinikai Központ ( Site 1319)
Szeged Csongrad, 6725, Hungary More Info
Study Coordinator
Contact
+3662545405
Petz Aladar Egyetemi Oktato Korhaz-Onkológiai Osztály ( Site 1321)
Gyor Gyor-Moson-Sopron, 9024, Hungary More Info
Study Coordinator
Contact
+36704511995
Országos Onkológiai Intézet-Urogenitális Tumorok és Klinikai Farmakológiai Osztály ( Site 1316)
Budapest Pest, 1122, Hungary More Info
Study Coordinator
Contact
3612248600
Somogy Megyei Kaposi Mór Oktató Kórház-Oncology center ( Site 1311)
Kaposvár Somogy, 7400, Hungary More Info
Study Coordinator
Contact
+36304111268
Debreceni Egyetem Klinikai Kozpont-Onkológiai Klinika ( Site 1310)
Debrecen , 4032, Hungary More Info
Study Coordinator
Contact
3652255840
Tallaght University Hospital ( Site 1402)
Dublin 24 Dublin, D24 N, Ireland More Info
Study Coordinator
Contact
35314144208
St. Vincent's University Hospital ( Site 1401)
Dublin 4 Dublin, , Ireland More Info
Study Coordinator
Contact
35314144208
Beaumont Hospital, Dublin-Cancer Clinical Trials & Research Unit ( Site 1403)
Dublin , 00009, Ireland More Info
Study Coordinator
Contact
0876130775
Rambam Health Care Campus-Oncology ( Site 1502)
Haifa , 31096, Israel More Info
Study Coordinator
Contact
+ 972 4 7776750
Rabin Medical Center-Oncology ( Site 1503)
Petah-Tikva , 49414, Israel More Info
Study Coordinator
Contact
97239378003
Sheba Medical Center-ONCOLOGY ( Site 1504)
Ramat Gan , 52656, Israel More Info
Study Coordinator
Contact
97235302191
Sourasky Medical Center-Oncology ( Site 1501)
Tel Aviv , 64239, Israel More Info
Study Coordinator
Contact
+ 972 972 3 6947284
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori-Oncologia Medica ( Site 1603)
Meldola Emilia-Romagna, 47014, Italy More Info
Study Coordinator
Contact
0543739426
Fondazione Policlinico Universitario Agostino Gemelli-Medical Oncology ( Site 1604)
Roma Lazio, 00168, Italy More Info
Study Coordinator
Contact
+390630154953
Ospedale San Raffaele-Oncologia Medica ( Site 1606)
Milano Lombardia, 20132, Italy More Info
Study Coordinator
Contact
+390226435789
Fondazione IRCCS Istituto Nazionale dei Tumori-Struttura Complessa Oncologia Medica 1 ( Site 1608)
Milan Lombardia, 20133, Italy More Info
Study Coordinator
Contact
00390223904450
Azienda Sanitaria Ospedaliera S Luigi Gonzaga-SCDU Oncologia Medica ( Site 1602)
Orbassano Piemonte, 10043, Italy More Info
Study Coordinator
Contact
390119026993
A.O.U.C. Policlinico di Bari ( Site 1607)
Bari Puglia, 70124, Italy More Info
Study Coordinator
Contact
+390805594167
Azienda Ospedaliera Universitaria Careggi-SOD ONCOLOGIA MEDICA ( Site 1601)
Firenze Toscana, 50134, Italy More Info
Study Coordinator
Contact
0557947298
IRCCS - AOU di Bologna-Oncologia Medica Ardizzoni ( Site 1605)
Bologna , 40138, Italy More Info
Study Coordinator
Contact
+39 0512142575
Azienda Ospedaliera Santa Maria Terni-SC Oncologia ( Site 1609)
Terni , 05100, Italy More Info
Study Coordinator
Contact
390744205410
Fujita Health University ( Site 1709)
Toyoake Aichi, 470-1, Japan More Info
Study Coordinator
Contact
+81-562-93-2111
National Cancer Center Hospital East ( Site 1704)
Kashiwa Chiba, 277-8, Japan More Info
Study Coordinator
Contact
+81-4-7133-1111
Toho University Sakura Medical Center ( Site 1718)
Sakura Chiba, 285-8, Japan More Info
Study Coordinator
Contact
+81-43-462-8811
Ehime University Hospital ( Site 1714)
Toon Ehime, 791-0, Japan More Info
Study Coordinator
Contact
+81-89-964-5111
Sapporo Medical University Hospital ( Site 1702)
Sapporo Hokkaido, 060-8, Japan More Info
Study Coordinator
Contact
+81-11-611-2111
Hokkaido University Hospital ( Site 1701)
Sapporo Hokkaido, 060-8, Japan More Info
Study Coordinator
Contact
+81-11-716-1161
Kanagawa cancer center ( Site 1703)
Yokohama Kanagawa, 241-8, Japan More Info
Study Coordinator
Contact
+81-45-520-2222
Nara Medical University Hospital ( Site 1712)
Kashihara Nara, 634-8, Japan More Info
Study Coordinator
Contact
+81-744-22-3051
Bell Land General Hospital ( Site 1710)
Sakai Osaka, 599-8, Japan More Info
Study Coordinator
Contact
+81-72-234-2001
Osaka University Hospital ( Site 1711)
Suita Osaka, 565-0, Japan More Info
Study Coordinator
Contact
+81-6-6879-5111
Hamamatsu University Hospital ( Site 1708)
Hamamatsu Shizuoka, 431-3, Japan More Info
Study Coordinator
Contact
+81-53-435-2111
Toranomon Hospital ( Site 1706)
Minato-ku Tokyo, 10584, Japan More Info
Study Coordinator
Contact
+81-3-3588-1111
Toyama University Hospital ( Site 1713)
Toyoma Toyama, 930-0, Japan More Info
Study Coordinator
Contact
+81-76-434-2315
Kyushu University Hospital ( Site 1715)
Fukuoka , 812-8, Japan More Info
Study Coordinator
Contact
+81-92-641-1151
Kagoshima University Hospital ( Site 1719)
Kagoshima , 890-8, Japan More Info
Study Coordinator
Contact
+81-99-275-5111
Kumamoto University ( Site 1716)
Kumamoto , 860-8, Japan More Info
Study Coordinator
Contact
+81-96-344-2111
Okayama University Hospital ( Site 1720)
Okayama , 700-8, Japan More Info
Study Coordinator
Contact
+81-86-223-7151
Nippon Medical School Hospital ( Site 1705)
Tokyo , 113-8, Japan More Info
Study Coordinator
Contact
+81-3-3822-2131
Tokyo Women's Medical University Adachi Medical Center ( Site 1717)
Tokyo , 123-8, Japan More Info
Study Coordinator
Contact
+81-3-3857-0111
Keio university hospital ( Site 1707)
Tokyo , 160-8, Japan More Info
Study Coordinator
Contact
+81-3-3353-1211
Wakayama Medical University Hospital ( Site 1721)
Wakayama , 641-8, Japan More Info
Study Coordinator
Contact
+81-73-447-2300
National Cancer Center-Center for Urologic Cancer ( Site 2604)
Goyang-si Kyonggi-do, 10408, Korea, Republic of More Info
Study Coordinator
Contact
+82 31-920-0114
Seoul National University Bundang Hospital-Urology ( Site 2602)
Seongnam Kyonggi-do, 13620, Korea, Republic of More Info
Study Coordinator
Contact
82317877342
Asan Medical Center-Oncology ( Site 2601)
Songpagu Seoul, 05505, Korea, Republic of More Info
Study Coordinator
Contact
82230105977
Samsung Medical Center ( Site 2603)
Seoul , 06351, Korea, Republic of More Info
Study Coordinator
Contact
+82 1599-3114
University Malaya Medical Centre ( Site 1804)
Lembah Pantai Kuala Lumpur, 59100, Malaysia More Info
Study Coordinator
Contact
+60378414000
Hospital Pulau Pinang ( Site 1806)
George Town Pulau Pinang, 10450, Malaysia More Info
Study Coordinator
Contact
+6042225768
Terapias Integrales del Riñon SA de CV ( Site 1910)
Guadalajara Jalisco, 44260, Mexico More Info
Study Coordinator
Contact
+523318414819
Hospital Civil Fray Antonio Alcalde-Oncology ( Site 1906)
Guadalajara Jalisco, 44280, Mexico More Info
Study Coordinator
Contact
+52 3322648799
Christus Muguerza Clinica Vidriera ( Site 1903)
Monterrey Nuevo Leon, 64570, Mexico More Info
Study Coordinator
Contact
+5218110623583
iCan Oncology Center Centro Medico AVE ( Site 1901)
Monterrey Nuevo Leon, 64710, Mexico More Info
Study Coordinator
Contact
8116597296
Hospital H+ Queretaro ( Site 1905)
Santiago de Queretaro Queretaro, 76000, Mexico More Info
Study Coordinator
Contact
+52 4422428555
BRCR Global Mexico - Queretaro-SMIQ ( Site 1907)
Santiago de Querétaro Queretaro, 76070, Mexico More Info
Study Coordinator
Contact
+52 442 195 9392
Centro de Oncología Personalizada ( Site 1911)
Culiacán Sinaloa, 80040, Mexico More Info
Study Coordinator
Contact
6671000522
Centro de Investigacion Clinica de Oaxaca ( Site 1904)
Oaxaca , 68020, Mexico More Info
Study Coordinator
Contact
+529516035559
Oncocenter ( Site 1909)
Puebla , 72530, Mexico More Info
Study Coordinator
Contact
+524151580443
Ziekenhuis Rijnstate-Rijnstate Centrum Oncologisch Onderzoek ( Site 3113)
Arnhem Gelderland, 6815 , Netherlands More Info
Study Coordinator
Contact
+31880057526
Maastricht UMC+ ( Site 3104)
Maastricht Limburg, 6229 , Netherlands More Info
Study Coordinator
Contact
0031433876543
Amphia Ziekenhuis, locatie Breda Molengracht ( Site 3103)
Breda Noord-Brabant, 4818 , Netherlands More Info
Study Coordinator
Contact
+3176595 5000
Maxima Medisch Centrum, locatie Eindhoven ( Site 3116)
Eindhoven Noord-Brabant, 5600 , Netherlands More Info
Study Coordinator
Contact
+31408886154
Tergooiziekenhuizen, locatie Hilversum ( Site 3102)
Hilversum Noord-Holland, 1213 , Netherlands More Info
Study Coordinator
Contact
+31887535153
Spaarne Gasthuis - Hoofddorp-Oncology ( Site 3107)
Hoofddorp Noord-Holland, 2134 , Netherlands More Info
Study Coordinator
Contact
+31232240000
Haga Ziekenhuis locatie Leyweg-Oncology ( Site 3108)
Den Haag Zuid-Holland, 2545 , Netherlands More Info
Study Coordinator
Contact
+31702104088
Franciscus Gasthuis & Vlietland, Locatie Vlietland ( Site 3101)
Schiedam Zuid-Holland, 3118 , Netherlands More Info
Study Coordinator
Contact
+31104612692
St. Antonius Ziekenhuis, locatie Utrecht-Interne geneeskunde ( Site 3112)
Utrecht , 3543 , Netherlands More Info
Study Coordinator
Contact
31306099111
Universitair Medisch Centrum Utrecht-Medical Oncology ( Site 3106)
Utrecht , 3584 , Netherlands More Info
Study Coordinator
Contact
31887556308
Uniwersytecki Szpital Kliniczny im. Jana Mikulicza-Radeckiego we Wrocławiu ( Site 2309)
Wrocław Dolnoslaskie, 50-55, Poland More Info
Study Coordinator
Contact
48601143281
Centrum Onkologii im. Prof. Franciszka Lukaszczyka-Ambulatorium Chemioterapii ( Site 2307)
Bydgoszcz Kujawsko-pomorskie, 85796, Poland More Info
Study Coordinator
Contact
48501446778
Szpital Wojewódzki im. Świętego Lukasza SP ZOZ w Tarnowie ( Site 2311)
Tarnow Malopolskie, 33-10, Poland More Info
Study Coordinator
Contact
48602280826
Mazowiecki Szpital Wojewódzki w Siedlcach-Siedleckie Centrum Onkologii ( Site 2313)
Siedlce Mazowieckie, 08-11, Poland More Info
Study Coordinator
Contact
48698826497
Luxmed Onkologia sp. z o. o. ( Site 2303)
Warszawa Mazowieckie, 01-74, Poland More Info
Study Coordinator
Contact
48691666578
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie - Panstwowy Instytut Badawczy w Warszawie (
Warszawa Mazowieckie, 02-78, Poland More Info
Study Coordinator
Contact
48225462331
Wojewodzki Szpital im. Sw. Ojca Pio w Przemyslu ( Site 2306)
Przemysl Podkarpackie, 37-70, Poland More Info
Study Coordinator
Contact
661957237
Przychodnia Lekarska KOMED ( Site 2304)
Konin Wielkopolskie, 62-50, Poland More Info
Study Coordinator
Contact
63 242 80 09
Szpital Kliniczny im. Przemienienia Panskiego Uniwersytetu M-chemotherapy department ( Site 2312)
Poznań Wielkopolskie, 60-56, Poland More Info
Study Coordinator
Contact
48601569568
Szpital Wojewódzki im. Mikoaja Kopernika w Koszalinie-Oddzial Dzienny Chemioterapii ( Site 2302)
Koszalin Zachodniopomorskie, 75-58, Poland More Info
Study Coordinator
Contact
+48502204953
Twoja Przychodnia - Szczecinskie Centrum Medyczne ( Site 2315)
Szczecin Zachodniopomorskie, 71-43, Poland More Info
Study Coordinator
Contact
+48608430889
National Cancer Centre Singapore ( Site 3601)
Singapore Central Singapore, 16961, Singapore More Info
Study Coordinator
Contact
+6564368000
Hospital Universitari de Girona Doctor Josep Trueta ( Site 2707)
Girona Gerona, 17007, Spain More Info
Study Coordinator
Contact
+34972225828
Hospital Universitario Ramón y Cajal-Medical Oncology ( Site 2710)
Madrid Madrid, Comunidad De, 28034, Spain More Info
Study Coordinator
Contact
+34913368263
Hospital Universitario 12 de Octubre-Medical Oncology ( Site 2708)
Madrid Madrid, Comunidad De, 28041, Spain More Info
Study Coordinator
Contact
+34913908339
Fundación Instituto Valenciano de Oncología ( Site 2705)
Valencia Valenciana, Comunitat, 46009, Spain More Info
Study Coordinator
Contact
+34961104605
Hospital Universitari Vall d'Hebron-Departamento de Oncologia- VHIO ( Site 2702)
Barcelona , 08035, Spain More Info
Study Coordinator
Contact
+34934894350
Hospital Lucus Augusti-Oncology ( Site 2706)
Lugo , 27003, Spain More Info
Study Coordinator
Contact
+34982296459
Hospital Clinico San Carlos-Oncology Department ( Site 2703)
Madrid , 28040, Spain More Info
Study Coordinator
Contact
+34913303000 x3133
Hospital Universitario Virgen de la Victoria-Phase II-III-IV Trials ( Site 2709)
Malaga , 29010, Spain More Info
Study Coordinator
Contact
+34951032508
Chang Gung Memorial Hospital at Kaohsiung-Oncology and Hematology ( Site 2905)
Kaohsiung Niao Sung Dist Kaohsiung, 83301, Taiwan More Info
Study Coordinator
Contact
886-2-28757519 ext. 315
Tri-Service General Hospital ( Site 2908)
Taipei City Taipei, 114, Taiwan More Info
Study Coordinator
Contact
886-2-87923311 ext. 13480
Kaohsiung Veterans General Hospital ( Site 2901)
Kaohsiung , 81362, Taiwan More Info
Study Coordinator
Contact
+886-7-3422121
China Medical University Hospital-Department of Urology ( Site 2907)
Taichung , 40447, Taiwan More Info
Study Coordinator
Contact
886-4-22052121 ext. 4440
Taichung Veterans General Hospital ( Site 2902)
Taichung , 407, Taiwan More Info
Study Coordinator
Contact
+886423592525 ext.5121
National Taiwan University Hospital ( Site 2904)
Taipei , 10002, Taiwan More Info
Study Coordinator
Contact
886-2-23123456
Taipei Veterans General Hospital ( Site 2903)
Taipei , 11217, Taiwan More Info
Study Coordinator
Contact
886228757519x315
Chang Gung Medical Foundation-Linkou Branch-Urology ( Site 2906)
Taoyuan , 333, Taiwan More Info
Study Coordinator
Contact
886-975366241
Chulalongkorn University ( Site 3005)
Bangkok Krung Thep Maha Nakhon, 10330, Thailand More Info
Study Coordinator
Contact
+6622564533
Ramathibodi Hospital ( Site 3001)
Bangkok Krung Thep Maha Nakhon, 10400, Thailand More Info
Study Coordinator
Contact
+6622011671
Faculty of Medicine Siriraj Hospital ( Site 3002)
Bangkok Krung Thep Maha Nakhon, 10700, Thailand More Info
Study Coordinator
Contact
+6624194488
Songklanagarind hospital ( Site 3004)
Hatyai Songkhla, 90110, Thailand More Info
Study Coordinator
Contact
+6674451469
Istanbul Universitesi Cerrahpasa-Internal Diseases ( Site 3204)
Istanbul- Fatih Istanbul, 34098, Turkey More Info
Study Coordinator
Contact
+902124400000
Baskent University Dr. Turgut Noyan Research and Training Center-ONCOLOGY ( Site 3208)
Adana , 01250, Turkey More Info
Study Coordinator
Contact
905325005269
Ankara Gülhane Eitim ve Aratrma Hastanesi-Oncology ( Site 3207)
Ankara , 06010, Turkey More Info
Study Coordinator
Contact
+905366401020
Ankara University Hospital Cebeci ( Site 3209)
Ankara , 06100, Turkey More Info
Study Coordinator
Contact
+905337483275
Hacettepe Universitesi-oncology hospital ( Site 3203)
Ankara , 06230, Turkey More Info
Study Coordinator
Contact
+905334318506
Ankara City Hospital-Medical Oncology ( Site 3206)
Ankara , 06800, Turkey More Info
Study Coordinator
Contact
+905555306271
TC Saglik Bakanligi Goztepe Prof. Dr. Suleyman Yalcin Sehir Hastanesi-oncology ( Site 3201)
Istanbul , 34722, Turkey More Info
Study Coordinator
Contact
905063509061
Ege University Medicine of Faculty-Medical Oncology ( Site 3202)
Izmir , 35100, Turkey More Info
Study Coordinator
Contact
+905324510608
The Christie NHS Foundation Trust ( Site 3301)
Manchester England, M20 4, United Kingdom More Info
Study Coordinator
Contact
+44 161 918 7217
City Hospital, Nottingham University Hospitals ( Site 3303)
Nottingham England, NG5 1, United Kingdom More Info
Study Coordinator
Contact
441158231851
Charing Cross Hospital ( Site 3302)
London Hammersmith And Fulham, W6 8R, United Kingdom More Info
Study Coordinator
Contact
442033110277
Singleton Hospital ( Site 3306)
Swansea , SA2 8, United Kingdom More Info
Study Coordinator
Contact
01792285520

How clear is this clinincal trial information?

Study is for people with:

Melanoma

Phase:

Phase 3

Estimated Enrollment:

1600

Study ID:

NCT05239728

Recruitment Status:

Recruiting

Sponsor:


Merck Sharp & Dohme LLC

How clear is this clinincal trial information?

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