Melanoma Clinical Trial

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Determining the Lymphokine Activated Killer (LAK) Cytotoxicity Present in Patients Undergoing Interleukin-2 Therapy

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Summary

Therapy with Interleukin-2 stimulates lymphocytes in humans to become Lymphokine-activated Killer cells (LAK). This study will determine if these killer cells are able to kill certain standard cell-lines in the laboratory.

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Full Description

Blood samples will be taken from patients undergoing outpatient Interleukin-2 therapy to measure the LAK cytotoxicity at baseline, after 1 cycle of therapy and 2 months later. The LAK cytotoxicity assay will be a standard colorimetric assay that measures lactic dehydrogenase release from lysed cells.

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Eligibility Criteria

Inclusion Criteria:

Patients must be undergoing Interleukin-2 therapy under the care of physicians at Loma Linda University Cancer Center
Patients must sign and give written informed consent in accordance with institutional and federal guidelines

Exclusion Criteria:

Patients not undergoing Interleukin-2 therapy under the care of physicians at Loma Linda University Cancer Center

Study is for people with:

Melanoma

Estimated Enrollment:

11

Study ID:

NCT01068470

Recruitment Status:

Terminated

Sponsor:

Loma Linda University

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There is 1 Location for this study

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Loma Linda University Cancer Center
Beaumont California, 92223, United States

How clear is this clinincal trial information?

Study is for people with:

Melanoma

Estimated Enrollment:

11

Study ID:

NCT01068470

Recruitment Status:

Terminated

Sponsor:


Loma Linda University

How clear is this clinincal trial information?

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