Melanoma Clinical Trial

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Efficacy Study of Nivolumab Compared to Ipilimumab in Prevention of Recurrence of Melanoma After Complete Resection of Stage IIIb/c or Stage IV Melanoma

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Summary

The purpose of this study is to determine whether nivolumab is better than ipilimumab to prevent recurrence of melanoma.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

At least 15 years of age Except: where local regulations and/or institutional policies do not allow for subjects < 18 years of age (pediatric population) to participate. For those sites, the eligible subject population is ≥ 18 years of age
Completely removed melanoma by surgery performed within 12 weeks of randomization
Stage IIIb/C or Stage IV before complete resection
No previous anti-cancer treatment

Exclusion Criteria:

Ocular or uveal melanoma
History of carcinomatosis meningitis
History of auto-immune disease
Treatment directed against the resected melanoma that is administrated after the surgery

Other protocol-defined inclusion/exclusion criteria apply

Study is for people with:

Melanoma

Phase:

Phase 3

Estimated Enrollment:

906

Study ID:

NCT02388906

Recruitment Status:

Active, not recruiting

Sponsor:

Bristol-Myers Squibb

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There are 131 Locations for this study

See Locations Near You

Local Institution - 0036
Little Rock Arkansas, 72205, United States
Local Institution - 0117
La Jolla California, 92093, United States
Local Institution - 0189
Los Angeles California, 90025, United States
Local Institution - 0021
San Francisco California, 94109, United States
Local Institution - 0006
San Francisco California, 94143, United States
Local Institution - 0010
Aurora Colorado, 80045, United States
Local Institution - 0004
Washington District of Columbia, 20007, United States
Local Institution - 0012
Jacksonville Florida, 32207, United States
Local Institution - 0019
Miami Beach Florida, 33140, United States
Local Institution - 0030
Orlando Florida, 32806, United States
Local Institution - 0032
Tampa Florida, 33612, United States
Local Institution - 0016
Atlanta Georgia, 30322, United States
Local Institution - 0106
Chicago Illinois, 60637, United States
Local Institution - 0013
Boston Massachusetts, 02215, United States
Local Institution - 0170
Boston Massachusetts, 02215, United States
Local Institution - 0171
Boston Massachusetts, 02215, United States
Local Institution - 0015
Ann Arbor Michigan, 48109, United States
Local Institution - 0002
Fridley Minnesota, 55432, United States
Local Institution - 0017
Saint Louis Missouri, 63110, United States
Local Institution - 0123
Hackensack New Jersey, 07601, United States
Local Institution - 0095
New Brunswick New Jersey, 08903, United States
Local Institution - 0024
New York New York, 10016, United States
Local Institution - 0033
New York New York, 10065, United States
Local Institution - 0003
Charlotte North Carolina, 28204, United States
Local Institution - 0025
Durham North Carolina, 27710, United States
Local Institution - 0157
Columbus Ohio, 43210, United States
Local Institution - 0031
Portland Oregon, 97213, United States
Local Institution - 0029
Portland Oregon, 97239, United States
Local Institution - 0022
Allentown Pennsylvania, 18103, United States
Local Institution - 0001
Bethlehem Pennsylvania, 18015, United States
Local Institution - 0026
Charleston South Carolina, 29425, United States
Local Institution - 0014
Nashville Tennessee, 37203, United States
Local Institution - 0005
Dallas Texas, 75246, United States
Local Institution - 0027
Charlottesville Virginia, 22908, United States
Local Institution - 0126
Seattle Washington, 98109, United States
Local Institution - 0142
Capital Federal Buenos Aires, 1426, Argentina
Local Institution - 0140
San Miguel de Tucuman Tucuman, 4000, Argentina
Local Institution
Cordoba , 5000, Argentina
Local Institution - 0079
Gateshead New South Wales, 2290, Australia
Local Institution - 0080
Westmead New South Wales, 2145, Australia
Local Institution - 0078
Wollstonecraft New South Wales, 2065, Australia
Local Institution - 0082
Greenslopes Queensland, 4120, Australia
Local Institution - 0083
Southport Queensland, 4215, Australia
Local Institution - 0084
Adelaide South Australia, 5000, Australia
Local Institution - 0075
Heidelberg Victoria, 3084, Australia
Local Institution - 0077
Prahran Victoria, 3181, Australia
Local Institution - 0085
Nedlands Western Australia, 6009, Australia
Local Institution - 0081
Camperdown , 2050, Australia
Local Institution - 0169
Graz , 8036, Austria
Local Institution - 0168
Salzburg , 5020, Austria
Local Institution - 0038
Brussels , 1090, Belgium
Local Institution - 0040
Bruxelles , 1200, Belgium
Local Institution - 0037
Gent , 9000, Belgium
Local Institution - 0039
Leuven , 3000, Belgium
Local Institution - 0051
Edmonton Alberta, T6G 1, Canada
Local Institution - 0074
Vancouver British Columbia, V5Z 4, Canada
Local Institution - 0094
Toronto Ontario, M5G 2, Canada
Local Institution - 0105
Montreal Quebec, H3T 1, Canada
Local Institution - 0046
Quebec City Quebec, G1J 1, Canada
Local Institution - 0101
Hradec Kralove , 500 0, Czechia
Local Institution - 0102
Ostrava-Poruba , 708 5, Czechia
Local Institution - 0099
Praha 1 , 110 0, Czechia
Local Institution - 0100
Praha 2 , 128 0, Czechia
Local Institution - 0047
Helsinki , 00029, Finland
Local Institution - 0048
Tampere , 33521, Finland
Local Institution - 0138
Lille , 59037, France
Local Institution - 0135
Marseille Cedex 5 , 13385, France
Local Institution - 0134
Nantes , 44000, France
Local Institution - 0136
Paris , 75010, France
Local Institution - 0133
Pierre Benite , 69495, France
Local Institution - 0137
Toulouse Cedex 9 , 31059, France
Local Institution - 0086
Athens , 11526, Greece
Local Institution - 0087
Neo Faliro , 18547, Greece
Local Institution - 0163
Budapest , 1122, Hungary
Local Institution - 0166
Dublin 7 , 0, Ireland
Local Institution - 0063
Dublin , 01, Ireland
Local Institution - 0108
Dublin , 4, Ireland
Local Institution - 0064
Galway , , Ireland
Local Institution - 0112
Bergamo , 24127, Italy
Local Institution - 0116
Genova , 16128, Italy
Local Institution - 0115
Meldola (FC) , 47014, Italy
Local Institution - 0113
Milano , 20133, Italy
Local Institution - 0107
Napoli , 80131, Italy
Local Institution - 0111
Padova , Padov, Italy
Local Institution - 0114
Roma , 00144, Italy
Local Institution - 0110
Siena , 53100, Italy
Local Institution - 0179
Nagoya-shi Aichi, 46685, Japan
Local Institution - 0161
Fukuoka-shi Fukuoka, 81285, Japan
Local Institution - 0174
Tsukuba-shi Ibaraki, 30585, Japan
Local Institution - 0162
Kumamoto-shi Kumamoto, 86085, Japan
Local Institution - 0160
Matsumoto-shi Nagano, 39086, Japan
Local Institution - 0175
Niigata-shi Niigata, 95185, Japan
Local Institution - 0176
Osaka-shi Osaka, 54000, Japan
Local Institution - 0159
Sunto-gun Shizuoka, 41187, Japan
Local Institution - 0158
Chuo-ku Tokyo, 10400, Japan
Local Institution - 0180
Chuo-shi Yamanashi, 40938, Japan
Local Institution - 0129
Seoul , 03080, Korea, Republic of
Local Institution - 0127
Seoul , 03722, Korea, Republic of
Local Institution - 0144
Seoul , 05505, Korea, Republic of
Local Institution - 0128
Seoul , 06351, Korea, Republic of
Local Institution - 0042
Amsterdam , 1081 , Netherlands
Local Institution - 0045
Groningen , 9714 , Netherlands
Local Institution - 0043
Nijmegen , 6525G, Netherlands
Local Institution - 0041
Veldhoven , 5504 , Netherlands
Local Institution - 0098
Bergen , 5021, Norway
Local Institution - 0109
Oslo , 3100, Norway
Local Institution - 0150
Gdansk , 80-21, Poland
Local Institution - 0149
Krakow , 31-11, Poland
Local Institution - 0152
Warszawa , 02-78, Poland
Local Institution - 0156
Craiova , 20054, Romania
Local Institution - 0153
Romania , 40001, Romania
Local Institution - 0148
Johannesburg Gauteng, 2196, South Africa
Local Institution - 0145
Pretoria Gauteng, 0075, South Africa
Local Institution - 0147
Saxonwold, Johannesburg Gauteng, 2196, South Africa
Local Institution - 0181
Cape Town Western CAPE, 7700, South Africa
Local Institution - 0146
Kraaifontein Western Cape, 7570, South Africa
Local Institution - 0120
Barcelona , 08036, Spain
Local Institution - 0119
Madrid , 28007, Spain
Local Institution - 0121
Sevilla , 41009, Spain
Local Institution - 0122
Valencia , 46014, Spain
Local Institution - 0050
Gothenberg , 413 4, Sweden
Local Institution - 0096
Lund , 221 8, Sweden
Local Institution - 0167
Zuerich , 8091, Switzerland
Local Institution - 0131
Kaohsiung , 833, Taiwan
Local Institution - 0132
Taichung , 404, Taiwan
Local Institution - 0130
Taoyuan , 333, Taiwan
Local Institution - 0057
Bristol Avon, BS2 8, United Kingdom
Local Institution - 0052
Swansea Carmarthenshire, SA2 8, United Kingdom
Local Institution - 0165
London Greater London, SW3 6, United Kingdom
Local Institution - 0054
Manchester Greater Manchester, M20 4, United Kingdom
Local Institution - 0056
Southampton Hampshire, SO16 , United Kingdom
Local Institution - 0177
Northwood Middlesex, HA6 2, United Kingdom
Local Institution - 0055
Oxford Oxfordshire, OX3 7, United Kingdom
Local Institution - 0060
Newcastle Upon Tyne Tyne And Wear, NE7 7, United Kingdom
Local Institution - 0097
Leicester , LE15W, United Kingdom
Local Institution - 0053
Surrey , SM2 5, United Kingdom
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How clear is this clinincal trial information?

Study is for people with:

Melanoma

Phase:

Phase 3

Estimated Enrollment:

906

Study ID:

NCT02388906

Recruitment Status:

Active, not recruiting

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

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