Melanoma Clinical Trial

Genetic Basis of Melanocytic Nevi

Summary

The objective of this protocol is to further elucidate the genetic mutations that drive melanocytic nevi (benign melanocytic neoplasms, moles). This will be performed by whole genome, whole exome, or targeted sequencing of de-identified specimens.

Herein, the investigators plan to isolate DNA from de-identified skin biopsy specimens and blood samples:

From melanocytic nevi collected by skin biopsy (a shave or punch biopsy). A part of the tissue will be submitted for routine diagnostic dermatopathology and investigational histomorphologic and immunohistochemical analysis.
From corresponding normal tissue (blood). DNA isolated from blood will be used as a normal control when analyzing sequencing data to identify somatic mutations in lesional tissue.

View Eligibility Criteria

Eligibility Criteria

Inclusion criteria:

Male or female subjects that are 18 years or older
Subjects with melanocytic nevi

Exclusion criteria:

Patients less than 18 years of age
Patients without melanocytic nevi
Patients with a bleeding disorder or are taking anticoagulation medication

Study is for people with:

Melanoma

Estimated Enrollment:

50

Study ID:

NCT03054584

Recruitment Status:

Recruiting

Sponsor:

University of California, Davis

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There is 1 Location for this study

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University of California-Davis, Department of Dermatology
Sacramento California, 95816, United States More Info
John Robb
Contact
916-551-2636
[email protected]

How clear is this clinincal trial information?

Study is for people with:

Melanoma

Estimated Enrollment:

50

Study ID:

NCT03054584

Recruitment Status:

Recruiting

Sponsor:


University of California, Davis

How clear is this clinincal trial information?

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