Randomised Study to Compare the Efficacy of AZD6244 vs TMZ

Inclusion Criteria:

Diagnosed with late stage malignant melanoma
Aged 18 or over
Female patients must be post-menopausal or with negative urine pregnancy test if pre-menopausal

Exclusion Criteria:

Any previous radiotherapy or chemotherapy (palliative radiotherapy is acceptable)
Participation in any other trial with an investigational product within the previous 30 days