Multiple Myeloma Clinical Trial

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A Comparative Clinical Study to Determine the Optimal Initial Therapy for Multiple Myeloma

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Summary

This study evaluates the outcomes of patients undergoing initial therapy for multiple myeloma.

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Full Description

PRIMARY OBJECTIVE:

I. Compare the overall survival between bortezomib, lenalidomide and dexamethasone (VRd), daratumumab, lenalidomide and dexamethasone (DRd) and daratumumab, bortezomib, lenalidomide and dexamethasone (DVRd) used as initial therapy for patients with newly diagnosed MM.

OUTLINE: This is an observational study.

Patients have their medical records reviewed on study.

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Eligibility Criteria

Inclusion Criteria:

Previously untreated active multiple myeloma starting a new treatment for the disease with one of the three established treatment regimens: VRd (bortezomib, lenalidomide, dexamethasone), DRd (daratumumab lenalidomide dexamethasone), or DVRd (daratumumab, bortezomib, lenalidomide, and dexamethasone)
No prior treatment for myeloma
Not receiving concurrent treatment for another active malignancy
No more than 3 months from start of treatment

Exclusion Criteria:

Does not meet all inclusion criteria

Study is for people with:

Multiple Myeloma

Estimated Enrollment:

2370

Study ID:

NCT06151717

Recruitment Status:

Recruiting

Sponsor:

Mayo Clinic

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There are 4 Locations for this study

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Mayo Clinic in Arizona
Scottsdale Arizona, 85259, United States More Info
Clinical Trials Referral Office
Contact
855-776-0015
[email protected]
Saurabh Chhabra, M.D.
Principal Investigator
Mayo Clinic in Florida
Jacksonville Florida, 32224, United States More Info
Clinical Trials Referral Office
Contact
855-776-0015
[email protected]
Sikander Ailawadhi, M.D.
Principal Investigator
Mayo Clinic in Rochester
Rochester Minnesota, 55905, United States More Info
Clinical Trials Referral Office
Contact
855-776-0015
[email protected]
Shaji K. Kumar, M.D.
Principal Investigator
Mayo Clinic Health System-Franciscan Healthcare
La Crosse Wisconsin, 54601, United States More Info
Clinical Trials Referral Office
Contact
855-776-0015
[email protected]
Anna C. Jones, M.D.
Principal Investigator

How clear is this clinincal trial information?

Study is for people with:

Multiple Myeloma

Estimated Enrollment:

2370

Study ID:

NCT06151717

Recruitment Status:

Recruiting

Sponsor:


Mayo Clinic

How clear is this clinincal trial information?

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