A Study of a Plant-Based Diet in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM)

Inclusion Criteria:

BMI ≥25
Confirmed diagnosis of MGUS or SMM
M spike (immunoglobulin) ≥0.2 g/dL or abnormal free light chain ratio with increased level of the appropriate involved light chain
Secretory disease
Age ≥18 years
Willingness to comply with all study-related procedures
ECOG performance status of 0-3
Interest to learn to cook plant based recipes

Exclusion Criteria:

Patients that already follow a whole foods plant based or vegan diet (ovo-lactovegetarian diets are not excluded)
Legume allergy
Severe allergies, such as anaphylactic shock to peanuts
Concurrent participation in weight loss/dietary/exercise programs
Mental impairment leading to inability to cooperate
Enrollment onto any other therapeutic investigational study
Concurrent pregnancy
Patients with a known diagnosis of diabetes mellitus will not be excluded but will need to be followed regularly with an endocrinologist/primary care physician during the trial period.
Positive HBV, HCV, HIV PCR testing
Non English speaking
≥ Grade 2 electrolyte abnormalities as defined by CTCAEv5.0 (need to be resolved before enrolling on study)
If in the opinion of the investigator there maybe any concerns regarding the ability of the patient to complete the study safely