Multiple Myeloma Clinical Trial

A Study of Real-life Current Standards of Care in Patients With Relapsed and/or Refractory Multiple Myeloma Who Received at Least 3 Prior Lines of Therapy Including Proteasome Inhibitor (PI), Immunomodulatory Drug (IMID), and Cluster of Differentiation 38 (CD38) Monoclonal Antibody Treatment

Summary

The purpose of this study is to assess the safety and clinical response including overall response rate (ORR) of real-life standard-of-care (SOC) treatments under routine clinical practice, over a 24-month period, in patients with relapsed/refractory multiple myeloma (RRMM).

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Have a documented diagnosis of multiple myeloma according to International myeloma working group (IMWG) diagnostic criteria
Received at least 3 prior lines of therapy or are double refractory to a proteasome inhibitor (PI) and an immunomodulatory agent (IMID) (induction with or without hematopoietic stem cell transplant and with or without maintenance therapy is considered a single regimen). Patients will have undergone at least 1 complete cycle of treatment for each regimen (unless progressive disease was the best response)
Must have documented evidence of progressive disease based on study physician's determination of response by the IMWG response criteria on or after the last regimen. Patients with documented evidence of progressive disease within the previous 6 months and who are refractory or nonresponsive to their most recent line of treatment afterwards are also eligible
Have an Eastern Cooperative Oncology Group (ECOG) Performance Status grade of 0 or 1
Must not be pregnant or must not plan to become pregnant within the study period

Study is for people with:

Multiple Myeloma

Estimated Enrollment:

248

Study ID:

NCT04035226

Recruitment Status:

Active, not recruiting

Sponsor:

Janssen-Cilag Ltd.

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There are 85 Locations for this study

See Locations Near You

Oncology Institute of Hope and Innovation
Tucson Arizona, 85745, United States
Oncology Institute of Hope and Innovation
Corona California, 92882, United States
Oncology Institute of Hope and Innovation
Glendale California, 91204, United States
Marin Cancer Center
Greenbrae California, 94904, United States
Asclepes Research
Weeki Wachee Florida, 34607, United States
Oncology Hematology Assoc of Central Illinois, P.C. d.b.a. Illinois CancerCare, P.C.
Peoria Illinois, 61615, United States
Providence Cancer Center
Southfield Michigan, 48075, United States
Central Care Cancer Center
Bolivar Missouri, 65613, United States
Washington University School of Medicine
Saint Louis Missouri, 63110, United States
Optum Care
Las Vegas Nevada, 89102, United States
Hunterdon Hematology Oncology
Flemington New Jersey, 08822, United States
The Cancer Institute at St. Francis Hospital
East Hills New York, 11548, United States
North Shore Hematology Oncology Associates, P.C.
East Setauket New York, 11733, United States
The Ohio State University
Columbus Ohio, 43210, United States
Grand Hôpital de Charleroi, site Notre Dame
Charleroi , 6000, Belgium
Universitair Ziekenhuis Antwerpen
Edegem , 2650, Belgium
UZ Leuven
Leuven , 3000, Belgium
Ucl de Mont-Godinne
Yvoir , 5530, Belgium
Centre Hospitalier du Mans
Le Mans , 72000, France
Centre Hospitalier Régional Universitaire de Lille, Hôpital Claude Huriez
Lille Cedex , 59000, France
CHU de Montpellier, Hopital Saint-Eloi
Montpellier , 34295, France
C.H.U. Hotel Dieu - France
Nantes , 44093, France
Hopital Saint-Louis
Paris cedex 10 , 75475, France
Hopital Saint-Antoine
PARIS cedex 12 , 75571, France
CHU de Bordeaux - Hôpital Haut-Lévêque
Pessac cedex , 33604, France
Centre hospitalier Lyon-Sud
Pierre-Bénite , 69495, France
CHU Poitiers - Hôpital la Milétrie
Poitiers , 86021, France
Pôle IUC Oncopole CHU
Toulouse cedex 9 , 31059, France
Universitätsklinik Hamburg-Eppendorf - Orthopädische Universitätsklinik und Poliklinik
Hamburg , 20251, Germany
Universitaetsklinikum Heidelberg
Heidelberg , 69120, Germany
Universitaetsklinikum Koeln
Koeln , 50397, Germany
Medizinische Klinik A
Muenster , 48149, Germany
Klinikum der Eberhard-Karls-Universität/Abt. für innere Med. II/Hämatologie/Onkologie-Germany
Tübingen , 72076, Germany
Universitätsklinikum Würzburg
Würzburg , 97080, Germany
U.O. Ematologia con Trapianto- AOU Policlinico di Bari
Bari , 70124, Italy
U.O. Ematologia Istituto Tumori Giovanni Paolo II
Bari , 70124, Italy
Istituto di Ematologia Seràgnoli azienda ospedaliera univeristaria Policlinico S.Orsola-Malpighi
Bologna , 40138, Italy
Policlinico di Catania
Catania , 95128, Italy
Azienda Ospedaliera Universitaria Careggi
Firenze , 50134, Italy
IRCCS Azienda Ospedaliera San Martino - IST
Genova , 16132, Italy
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori
Meldola , 47014, Italy
Universita degli Studi di Padova - Azienda Ospedaliera di Pa
Padova , 35128, Italy
Ospedale Villa Sofia-Cervello
Palermo , 90146, Italy
Fondazione IRCCS Policlinico San Matteo
Pavia , 27100, Italy
Irccs Crob
Rionero in Vulture , 85028, Italy
Università di Roma La Sapienza
Roma , 00161, Italy
Fondazione Policlinico Universitario A. Gemelli IRCCS
Rome , 00168, Italy
IRCCS Ospedale Casa Sollievo della Sofferenza
San Giovanni Rotondo , 71013, Italy
Ospedale Cardinale G. Panico
Tricase , 73039, Italy
A.O.U. Citta della Salute e della Scienza di Torino - Presidio Molinette
Turin , 10126, Italy
VU Medisch Centrum
Amsterdam , 1081 , Netherlands
UMCG
Groningen , 9713 , Netherlands
Erasmus MC - Satellite
Rotterdam , 3075 , Netherlands
Samodzielny Publiczny Zaklad Opieki Zdrowotnej Zespol Szpitali Miejskich
Chorzów , 41-50, Poland
Samodzielny Publiczny Szpital Kliniczny nr 1 w Lublinie
Lublin , 20-08, Poland
Szpital Kliniczny Przemienienia Panskiego Uniwersytetu Medycznego im. Karola Marcinkowskiego
Poznan , 60-56, Poland
S.P. Botkin Moscow City Clinical Hospital
Moscow , 12528, Russian Federation
City Clinical Hospital # 40
Moscow , 12930, Russian Federation
Nizhniy Novgorod Region Clinical Hospital
Nizhny Novgorod , 60312, Russian Federation
Samara Region Clinical Hospital
Samara , 44309, Russian Federation
Clinical Research Institute of Hematology and Transfusiology
St-Petersburg , 19102, Russian Federation
Hosp. Clinic I Provincial de Barcelona
Barcelona , 08036, Spain
Inst. Cat. Doncologia-H Duran I Reynals
Barcelona , 08908, Spain
Hosp. Puerta Del Mar
Cadiz , 11009, Spain
Hosp. de Jerez de La Frontera
Jerez de la Frontera , 11407, Spain
Hosp. de Leon
Leon , 24080, Spain
Hosp. Univ. Ramon Y Cajal
Madrid , 28034, Spain
Hosp. Univ. 12 de Octubre
Madrid , 28041, Spain
Hosp. Univ. Son Espases
Palma , 7120, Spain
Clinica Univ. de Navarra
Pamplona , 31008, Spain
Hosp. Clinico Univ. de Salamanca
Salamanca , 37007, Spain
Hosp. Univ. Marques de Valdecilla
Santander , 39008, Spain
Hosp. Mutua Terrassa
Terrassa , 08221, Spain
Hosp. Univ. Dr. Peset
Valencia , 46017, Spain
Hosp. Clinico Univ. de Valladolid
Valladolid , 47003, Spain
University Hospital Birmingham (QE)
Birmingham , B15 2, United Kingdom
Birmingham Heartlands Hospital
Birmingham , B9 5S, United Kingdom
Southmead Hospital
Bristol , BS10 , United Kingdom
Maidstone Hospital
Kent , ME16 , United Kingdom
King's College Hospital
London , SE5 9, United Kingdom
St George's Hospital
London , SW17 , United Kingdom
Manchester Royal Infirmary
Manchester , M13 9, United Kingdom
Wythenshawe Hospital
Manchester , M23 9, United Kingdom
Nottingham University Hospitals NHS Trust
Nottingham , NG5 1, United Kingdom
Sheffield Teaching Hospitals NHS Foundation Trust
Sheffield , S10 2, United Kingdom
The Royal Marsden NHS Trust Sutton
Surrey , SM2 5, United Kingdom

How clear is this clinincal trial information?

Study is for people with:

Multiple Myeloma

Estimated Enrollment:

248

Study ID:

NCT04035226

Recruitment Status:

Active, not recruiting

Sponsor:


Janssen-Cilag Ltd.

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.