Multiple Myeloma Clinical Trial
A Study to Determine the Recommended Dose and Regimen and to Evaluate the Safety and Preliminary Efficacy of CC-92480 in Combination With Standard Treatments in Participants With Relapsed or Refractory Multiple Myeloma (RRMM) and Newly Diagnosed Multiple Myeloma (NDMM)
Summary
The purpose of this study is to evaluate the safety and preliminary efficacy of CC-92480 in combination with standard treatments.
Eligibility Criteria
Inclusion Criteria:
• Eastern Cooperative Oncology Group (ECOG) performance status score of 0, 1 or 2
For participants in Cohorts A, B, C, D, E, F, H, I, J, and K the following inclusions will also apply:
Documented diagnosis of multiple myeloma (MM) and measurable disease
Documented disease progression during or after their last antimyeloma regimen
Achieved a response (minimal response [MR] or better) to at least 1 prior treatment regimen
Exclusion Criteria:
Plasma cell leukemia, Waldenstrom's macroglobulinemia, POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, and skin changes) or clinically significant amyloidosis
Known central nervous system (CNS) involvement with myeloma
Received immunosuppressive medication within the last 14 days of initiating study treatment
Uncontrolled hypertension or uncontrolled diabetes within 14 days prior to enrollment
Other protocol-defined inclusion/exclusion criteria apply
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There are 50 Locations for this study
Denver Colorado, 80218, United States
Tampa Florida, 33612, United States
Chicago Illinois, 60611, United States
Chicago Illinois, 60637, United States
Boston Massachusetts, 02115, United States More Info
Rochester Minnesota, 55905, United States
Hackensack New Jersey, 07601, United States
Winston-Salem North Carolina, 27157, United States
Nashville Tennessee, 37203, United States
Seattle Washington, 98104, United States
Ostrava-Poruba , 708 5, Czechia
Praha 2 , 128 0, Czechia
Vejle , 7100, Denmark
Berlin , 12203, Germany
Hamburg , 20246, Germany
Munchen , 81675, Germany
Reggio Emilia , 42100, Italy
Torino , 10126, Italy
Madrid , 28022, Spain
How clear is this clinincal trial information?