Multiple Myeloma Clinical Trial

Clinical Trial Finder Multiple Myeloma Trials

An Investigational Immuno-therapy Study of Nivolumab, Pomalidomide and Dexamethasone Combinations in Patients With Multiple Myeloma

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Summary

The purpose of this study is to evaluate the safety and effectiveness of several combination therapies for Multiple Myeloma. Upon entry into the study, patients will be randomized (assigned by chance) to receive either:

Group 1: nivolumab, pomalidomide and dexamethasone OR Group 2: pomalidomide and dexamethasone OR Group 3: nivolumab, elotuzumab, pomalidomide and dexamethasone.

Enrollment is closed for all groups.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Refractory or relapsed and refractory multiple myeloma
Measurable disease
Have received ≥ 2 lines of prior therapy which must have included an immune modulatory drug (IMiD) and a proteasome inhibitor alone or in combination

Exclusion Criteria:

Solitary bone or extramedullary plasmacytoma disease only
Active plasma cell leukemia

Other protocol defined inclusion/exclusion criteria apply

Study is for people with:

Multiple Myeloma

Phase:

Phase 3

Estimated Enrollment:

170

Study ID:

NCT02726581

Recruitment Status:

Completed

Sponsor:

Bristol-Myers Squibb

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There are 121 Locations for this study

See Locations Near You

Local Institution - 0020
Birmingham Alabama, 35294, United States
Local Institution - 0160
Mobile Alabama, 36608, United States
Local Institution - 0163
Fayetteville Arkansas, 72703, United States
Local Institution - 0118
Bakersfield California, 93309, United States
Local Institution - 0093
Corona California, 92879, United States
Local Institution - 0016
Fountain Valley California, 92708, United States
Local Institution - 0164
La Jolla California, 92037, United States
UC San Diego Moores Cancer Ctr
La Jolla California, 92093, United States
Local Institution - 0138
Los Angeles California, 90017, United States
Local Institution - 0155
Los Angeles California, 90095, United States
Local Institution - 0117
Redondo Beach California, 90277, United States
Local Institution - 0092
Riverside California, 92501, United States
Coastal Integrative Cancer Care
San Luis Obispo California, 93401, United States
Local Institution - 0113
Santa Maria California, 93454, United States
Colorado Blood Cancer Institute
Denver Colorado, 80218, United States
Poudre Valley Health Care
Fort Collins Colorado, 80528, United States
Local Institution - 0116
Grand Junction Colorado, 81501, United States
Yale University School Of Medicine
New Haven Connecticut, 06520, United States
Local Institution - 0147
Washington District of Columbia, 20007, United States
Local Institution - 0011
Boynton Beach Florida, 33426, United States
Florida Cancer Specialists S.
Fort Myers Florida, 33916, United States
Local Institution - 0114
Hollywood Florida, 33021, United States
Cancer Specialists of North FL
Jacksonville Florida, 32256, United States
Local Institution - 0082
Pensacola Florida, 32504, United States
Local Institution - 0126
Saint Petersburg Florida, 33705, United States
Local Institution - 0130
Tallahassee Florida, 32308, United States
Local Institution - 0125
West Palm Beach Florida, 33401, United States
Local Institution - 0119
Athens Georgia, 30607, United States
Local Institution - 0009
Atlanta Georgia, 30318, United States
Local Institution - 0024
Atlanta Georgia, 30322, United States
Augusta University
Augusta Georgia, 30912, United States
Local Institution - 0035
Chicago Illinois, 60612, United States
Local Institution - 0111
Fort Wayne Indiana, 46845, United States
Indiana University Cancer Ctr
Indianapolis Indiana, 46202, United States
Local Institution - 0018
Bethesda Maryland, 20817, United States
Local Institution - 0006
Baltimore Massachusetts, 21229, United States
Local Institution - 0123
Worcester Massachusetts, 01655, United States
Local Institution - 0150
Ypsilanti Michigan, 48197, United States
Local Institution - 0137
Hattiesburg Mississippi, 39401, United States
St. Louis Cancer Care, Llp
Bridgeton Missouri, 63044, United States
Local Institution - 0128
Kansas City Missouri, 64132, United States
Washington University
Saint Louis Missouri, 63110, United States
Local Institution - 0049
Springfield Missouri, 65806, United States
Local Institution - 0079
Lincoln Nebraska, 68510, United States
Local Institution - 0076
Flemington New Jersey, 08822, United States
Local Institution - 0002
Hackensack New Jersey, 07601, United States
Local Institution - 0095
New Brunswick New Jersey, 08903, United States
Local Institution - 0142
Paramus New Jersey, 07652, United States
Local Institution - 0010
Buffalo New York, 14263, United States
Broome Oncology LLC
Johnson City New York, 13790, United States
Mount Sinai Medical Center
New York New York, 10029, United States
Local Institution - 0017
New York New York, 10065, United States
Local Institution - 0001
Durham North Carolina, 27710, United States
Local Institution - 0096
Winston-Salem North Carolina, 27157, United States
Local Institution - 0012
Columbus Ohio, 43219, United States
University Of Oklahoma
Oklahoma City Oklahoma, 73104, United States
Local Institution - 0145
Portland Oregon, 97213, United States
Local Institution - 0136
Lancaster Pennsylvania, 17604, United States
Local Institution - 0021
Philadelphia Pennsylvania, 19104, United States
Local Institution - 0036
Sayre Pennsylvania, 18840, United States
Local Institution - 0152
Greenville South Carolina, 29605, United States
Local Institution - 0069
Germantown Tennessee, 38138, United States
Tennessee Oncology, PLLC - SCRI - PPDS
Nashville Tennessee, 37203, United States
Baylor Research Institute
Dallas Texas, 75246, United States
Local Institution - 0044
Houston Texas, 77090, United States
Local Institution - 0037
San Antonio Texas, 78229, United States
Local Institution - 0046
Temple Texas, 76508, United States
Local Institution - 0022
Ogden Utah, 84403, United States
Local Institution - 0153
Salt Lake City Utah, 84106, United States
Emily Couric Clinical Cancer Center
Charlottesville Virginia, 22908, United States
Virginia Cancer Institute
Richmond Virginia, 23230, United States
Local Institution - 0144
Seattle Washington, 98108, United States
Local Institution - 0029
Linz , 4020, Austria
Universitaetsklinik Salzburg
Salzburg , 5020, Austria
Local Institution - 0026
Vienna , 1090, Austria
Klinikum Wels-Grieskirchen Gmbh
Wels , 4600, Austria
Wilhelminenspital
Wien , 1160, Austria
Local Institution
Edmonton Alberta, T6G 1, Canada
Local Institution
Vancouver British Columbia, V5Z 1, Canada
Local Institution - 0074
Toronto Ontario, M5G 2, Canada
Local Institution - 0039
Montreal Quebec, H2X 3, Canada
MUHC - Glen Site
Montreal Quebec, H4A 3, Canada
Local Institution - 0154
Montreal Quebec, H4J 1, Canada
Local Institution - 0157
Rimouski Quebec, G5L 5, Canada
Local Institution
Quebec , G1R 2, Canada
Interni hematologicka a onkologicka klinika
Brno , 625 0, Czechia
Klinika hematoonkologie
Ostrava-Poruba , 708 5, Czechia
I. interni klinika - klinika hematologie 1. LF UK a VFN v Praze
Praha 2 , 128 0, Czechia
Local Institution
Aarhus , 8200, Denmark
Local Institution
Odense , 5000, Denmark
Local Institution - 0050
Berlin , 12200, Germany
Universitaetsklinikum Carl Gustav Carus
Dresden , 01307, Germany
Uniklinikum Duesseldorf
Duesseldorf , 40225, Germany
Local Institution - 0135
Kiel , 24105, Germany
Klinikum Der Johannes Gutenberg Universitaet Mainz
Mainz , 55101, Germany
Local Institution - 0054
Ulm , 89081, Germany
Alexandra General Hospital Of Athens
Athens , 11528, Greece
Local Institution - 0087
Beer Sheva , 84101, Israel
Local Institution
Jerusalem , 91120, Israel
Local Institution
Petah Tikva , 49414, Israel
Local Institution
Ramat-gan , 52621, Israel
Local Institution
Tel Aviv , 64239, Israel
Local Institution - 0042
Torino Piemonte, 10126, Italy
Azienda Ospedaliero Universitaria Ospedali Riuniti Di Ancona
Ancona , 60126, Italy
Local Institution - 0089
Bergamo , 24127, Italy
A. O. U. Di Bologna, Policlinico S. Orsola Malpighi
Bologna , 40138, Italy
Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori (IRST)
Meldola (FC) , 47014, Italy
Azienda Ospedaliera Santa Maria Terni
Terni , 05100, Italy
Local Institution
Oslo , 0372, Norway
Local Institution - 0075
Stavanger , 4011, Norway
Local Institution - 0132
Lisbon Lisboa, 1400-, Portugal
Local Institution
Porto , 4200-, Portugal
Local Institution - 0071
San Juan , 00918, Puerto Rico
Local Institution - 0101
Pozuelo De Alarcon Madrid, 28223, Spain
Local Institution - 0098
Badalona-Barcelona , 08916, Spain
Local Institution - 0100
Barcelona , 08035, Spain
Local Institution - 0097
Pamplona , 31008, Spain
Local Institution - 0099
Salamanca , 37007, Spain
Local Institution - 0064
Huddinge , 14186, Sweden
Hopitaux Universitaires de Geneve
Geneve , 1211, Switzerland
Local Institution - 0186
Istanbul , 34899, Turkey
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How clear is this clinincal trial information?

Study is for people with:

Multiple Myeloma

Phase:

Phase 3

Estimated Enrollment:

170

Study ID:

NCT02726581

Recruitment Status:

Completed

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

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