Multiple Myeloma Clinical Trial

Mycobiome Supporting Diet to Reduce GI Toxicity Associated With ASCT

Summary

The purpose of this study is to determine if this specific Mycobiome Supporting Diet (MSD diet) can help reduce gut inflammation during post-transplant period. The MSD is an special diet which will be explained in detail by a dietician that works by supporting the body's good gut bacteria and fungi.

View Full Description

Full Description

This is a non-randomized cohort study. Participants will be on a specific diet for 4 weeks prior to transplant and 10 days after transplant, and will then be asked to fill out several questionnaires during this period to see if this diet is easy and simple to follow. The questionnaires will be weekly while participants are outpatient and once admitted to the hospital, participants will need to fill it on the last day (10 days after stem cell infusion). Participants will also be requested to provide fecal swab samples which we will test for bacteria and fungi. A total of 3 samples will be taken at different time points during this study.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Eligible for first autologous transplant for myeloma
Willing to adhere to the allowed and disallowed foods of the diet plan.
Able to get and prepare their own food items for all meals during the study

Exclusion Criteria:

Active inflammatory bowel disease, celiac disease, other chronic intestinal disorders
Pregnant women, planning to get pregnant or breastfeeding
Prior bowel resection
Inability to tolerate the study diet due to allergies/ intolerance/ preference
Inability to consent to trial
Patients with restrictions in diet including inability to have oral nutrition with regular consistency
Any condition that the investigator feels may limit the volunteer's ability to complete the study protocol.
Patients with absolute neutrophil count (ANC) < 1000 on long term antibacterial prophylaxis ongoing 3 days prior to enrollment
Patients who received antifungal therapy in 3 days prior to enrollment
Patients who received steroid therapy in 7 days prior to enrollment

Study is for people with:

Multiple Myeloma

Study ID:

NCT04685525

Recruitment Status:

Withdrawn

Sponsor:

Case Comprehensive Cancer Center

Check Your Eligibility

Let’s see if you might be eligible for this study.

What is your age and gender ?

Submit

There is 1 Location for this study

See Locations Near You

University Hospitals Cleveland Medical Center, Case Comprehensive Cancer Center
Cleveland Ohio, 44106, United States

How clear is this clinincal trial information?

Study is for people with:

Multiple Myeloma

Study ID:

NCT04685525

Recruitment Status:

Withdrawn

Sponsor:


Case Comprehensive Cancer Center

How clear is this clinincal trial information?

×

Introducing, the Journey Bar

Use this bar to access information about the steps in your cancer journey.