Pilot Study of Multi-Modality Imaging in Patients With Hematologic Malignancies

Inclusion Criteria:

Diagnosis of hematologic malignancy and fitting into one of the following categories:

Newly diagnosed and/or day 14 post-induction chemotherapy
Relapsed, including relapse after hematopoietic cell transplant
Planned hematopoietic cell transplant (if enrolling at "close") or within 100 days post hematopoietic cell transplant (if enrolling post-transplant) with a preparative regimen that includes either total marrow irradiation (TMI) or total body irradiation (TBI)
Undergoing natural killer cell therapies (with or without subsequent transplant)
Aged 18 years and older
Not pregnant - women of childbearing potential will have a confirmatory pregnancy test prior to each imaging per routine procedures
Adequate renal function (estimated glomerular filtration rate > 60 ml/min) as determined by a serum creatinine level performed as a part of standard of care within 7 days of imaging
Able and willing to provide written consent

Exclusion Criteria:

Otherwise eligible patients meeting one or more of the contraindicates for an MRI, may enroll in the study without undergoing the MRI:

ferromagnetic implants
history of shrapnel or shot gun injury
too large to fit in the magnet (approximate body mass index ≥ 40)
cardiac pacemakers or other implanted devices that are not MR-compatible
claustrophobia
large tattoos