Multiple Myeloma Clinical Trial

Prospective Research Assessment in Multiple Myeloma: An Observational Evaluation (PREAMBLE)

Summary

The purpose of this study is to assess the clinical effectiveness of all approved multiple myeloma (MM) therapies in the newly-diagnosed (NDMM) and the relapsed/refractory MM (RRMM) settings in real-world clinical practice.

View Eligibility Criteria

Eligibility Criteria

For more information regarding Bristol-Myers Squibb Clinical Trial participation, please visit www.BMSStudyConnect.com

Inclusion Criteria:

For RRMM participants who have received at least one prior line of therapy (LoT) for MM:

Have documented progression from a prior LoT
Participants who have initiated treatment with one of the following therapies within 90 days before consent for this study OR in the case where treatment has not yet been initiated, documentation that the treatment strategy was determined before consent for this study must be provided, and treatment must be initiated within 30 days after consent:
IMiDs
PIs
Combination of IMiD + PI
Newer agents with novel MOAs alone or in combination (eg, mAbs, HDACIs, Akt inhibitors, SINE, or CAR T-cell therapies)

For NDMM participants receiving frontline therapy:

Eligible to receive frontline therapy for MM (no prior MM treatment)
Participants who have initiated treatment for MM with one of the following therapies within 90 days before consent for this study OR in the case where treatment has not yet been initiated, documentation that the treatment strategy was determined before consent for this study must be provided, and treatment must be initiated within 30 days after consent:
IMiDs
PIs
Combination of IMiD + PI
Newer agents with novel MOAs alone or in combination (eg, mAbs, HDACIs, Akt inhibitors, SINE, or CAR T-cell therapies)

Exclusion Criteria:

Participants who are currently participating in a clinical trial for MM
Participants who are currently receiving treatment for primary cancer other than MM
Participants who are not willing or able to provide informed consent
Participants who are incarcerated
Participants under compulsory detention for treatment of a physical (eg, infectious) or psychiatric illness

Other protocol-defined inclusion/exclusion criteria apply

Study is for people with:

Multiple Myeloma

Estimated Enrollment:

2555

Study ID:

NCT01838512

Recruitment Status:

Recruiting

Sponsor:

Bristol-Myers Squibb

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There are 136 Locations for this study

See Locations Near You

Local Institution
Birmingham Alabama, 35213, United States
Alabama Oncology
Birmingham Alabama, 35243, United States
Northwest Alabama Cancer Center PC
Muscle Shoals Alabama, 35661, United States
Local Institute
Goodyear Arizona, 85338, United States
Local Institution
Anaheim California, 92801, United States
Pacific Cancer Madical Center
Anaheim California, 92801, United States
East Valley Hematology And Oncology Medical Group
Burbank California, 91505, United States More Info
Raul Mena, Site 0045
Contact
Local Institution
Corona California, 92880, United States
The Oncology Institute Of Hope And Innovation
Downey California, 90241, United States
Compassionate Cancer Care Medical Group
Fountain Valley California, 92708, United States
Local Institute
Los Angeles California, 90013, United States
Local Institute
Santa Rosa California, 95403, United States
St Joseph Heritage Healthcare
Santa Rosa California, 95403, United States More Info
Wes Lee, Site 0051
Contact
MedStar Washington Hospital Center
Washington District of Columbia, 20010, United States
Florida Cancer Specialists & Research Institute
Brooksville Florida, 34613, United States
Local Institution
Brooksville Florida, 34613, United States
Michael and Dianne Bienes Cancer Center
Fort Lauderdale Florida, 33308, United States
Cancer Specialists of North Florida
Jacksonville Florida, 32256, United States
Local Institution
Jacksonville Florida, 32256, United States
Summit Cancer Care
Savannah Georgia, 31404, United States More Info
Grant Lewis, Site 0046
Contact
Local Institute
Valdosta Georgia, 31602, United States
Pearlman Cancer Center
Valdosta Georgia, 31602, United States More Info
Jianfeng Wang, Site 0047
Contact
Local Institution
Skokie Illinois, 60077, United States
SIU Simmons Cancer Institute
Springfield Illinois, 62794, United States More Info
Aziz-Ur-Rehman Khan, Site 0041
Contact
Local Institution - 0012
Urbana Illinois, 61801, United States
St. Vincent Anderson Regional Hospital
Anderson Indiana, 46016, United States
Indiana Blood and Marrow Transplantation LLC
Indianapolis Indiana, 46237, United States
Local Institution
Indianapolis Indiana, 46237, United States
Mercy Medical Center
Des Moines Iowa, 50314, United States
JENCC ACCRU Allianc Site
Sioux City Iowa, 51101, United States
Local Institute
Sioux City Iowa, 51101, United States
KentuckyOne Health and Oncology Associates
Lexington Kentucky, 40504, United States
Saint Joseph London
London Kentucky, 40741, United States
Local Institute
Louisville Kentucky, 40201, United States
Norton Cancer Institute
Louisville Kentucky, 40202, United States More Info
Don Stevens, Site 0042
Contact
Cancer Center of Acadiana at Lafayette General Health
Lafayette Louisiana, 70503, United States
Local Institution
Lafayette Louisiana, 70503, United States
Local Institution
Shreveport Louisiana, 71103, United States
Willis Knighton Cancer Center
Shreveport Louisiana, 71103, United States
Local Institution
Minneapolis Minnesota, 55404, United States
Minnesota Oncology Hematology, P.A.
Woodbury Minnesota, 55125, United States
University of Mississippi Medical Center
Jackson Mississippi, 39216, United States
Local Institute
Southaven Mississippi, 38671, United States
Local Institute
Kansas City Missouri, 64132, United States
Research Medical Center
Kansas City Missouri, 64132, United States More Info
Jaswinder Singh, Site 0050
Contact
Montana Cancer Institute Foundation
Missoula Missouri, 59802, United States More Info
Patrick Beatty, Site 0037
Contact
Local Institute
Saint Joseph Missouri, 64501, United States
Local Institution
Saint Louis Missouri, 63110, United States
Washington University School Of Medicine-St Louis
Saint Louis Missouri, 63110, United States
Local Institution
Springfield Missouri, 65804, United States
Mercy Medical Research Institute
Springfield Missouri, 65804, United States
Local Institute
Missoula Montana, 59802, United States
Local Institute
Missoula Montana, 59807, United States
Cancer Partners of Nebraska
Lincoln Nebraska, 68510, United States
Local Institute
Omaha Nebraska, 68124, United States
Oncology Hematology West, P.C.
Omaha Nebraska, 68124, United States
Bms Clinical Research Center
Does Not Exist New Jersey, 08690, United States More Info
Mr Bristol-Myers Squibb, Site 008
Contact
Stony Brook University Hospital
Stony Brook New York, 11794, United States More Info
Michael Schuster, Site 0049
Contact
Local Institute
Cary North Carolina, 27518, United States
Waverly Hematology Oncology
Cary North Carolina, 27518, United States More Info
Suzanne Kirby, Site 0033
Contact
Gaston Hematology & Oncology
Gastonia North Carolina, 28054, United States
Local Institution
Gastonia North Carolina, 28054, United States
Gabrail Cancer Center Research
Canton Ohio, 44718, United States
Local Institute
Canton Ohio, 44718, United States
Local Institute
Cleveland Ohio, 44109, United States
MetroHealth Medical Center
Cleveland Ohio, 44109, United States
Local Institute
Tulsa Oklahoma, 74136, United States
Tulsa Cancer Institute PLLC
Tulsa Oklahoma, 74146, United States
Local Institute
Portland Oregon, 97200, United States
Local Institute
Pottstown Pennsylvania, 19464, United States
Pottstown Hospital Tower Health - Oncology
Pottstown Pennsylvania, 19464, United States More Info
Wei Song, Site 0043
Contact
Charleston Oncology
Charleston South Carolina, 29414, United States
Local Institute
Charleston South Carolina, 29414, United States
Local Institute
Knoxville Tennessee, 37920, United States
University of Tennessee Medical Center
Knoxville Tennessee, 37920, United States More Info
Wahid Hanna, Site 0038
Contact
Baptist Cancer Center
Memphis Tennessee, 38120, United States More Info
Donald Gravenor, Site 0035
Contact
Local Institution
Memphis Tennessee, 38120, United States
Local Institute
Amarillo Texas, 79106, United States
Texas Oncology - Amarillo
Amarillo Texas, 79106, United States
St. Joseph Health Cancer Center
Bryan Texas, 77802, United States
Local Institute
Corpus Christi Texas, 78350, United States
Local Institute
Dallas Texas, 75229, United States
Dallas Presbyterian Hospital - Texas Oncology PA
Dallas Texas, 75231, United States
Local Institute
Dallas Texas, 75231, United States
Local Institute
Dallas Texas, 75390, United States
UT Southwestern Medical Center
Dallas Texas, 75390, United States
Texas Oncology-Garland
Garland Texas, 75042, United States More Info
Manish Gupta, Site 0032
Contact
Cancer Care Centers Of South Texas
San Antonio Texas, 78217, United States
Local Institute
San Antonio Texas, 78217, United States
Local Institute
Sherman Texas, 75090, United States
Texas Oncology - Denison
Sherman Texas, 75090, United States
Local Institute
Seattle Washington, 98101, United States
VA Puget Sound Health Care System
Seattle Washington, 98108, United States More Info
Robert Richard, Site 0039
Contact
Cancer Care Northwest
Spokane Washington, 99202, United States
Local Institute
Spokane Washington, 99202, United States
Local Institute
Yakima Washington, 98901, United States
Local Institute
Yakima Washington, 98902, United States
Yakima Valley Memorial Hospital
Yakima Washington, 98902, United States More Info
Thomas Boyd, Site 0031
Contact
Local Institution
Toronto Ontario, M3M 0, Canada
Local Institute
Toronto Ontario, M4N 3, Canada
Local Institution - 0066
Toronto Ontario, M5G 2, Canada
Local Institute
Weston Ontario, M9N 1, Canada
Local Institute
Blois , , France
Local Institution
Cannes Cedex , 06414, France
Local Institution
Chalon sur Saone , 71100, France
Local Institute
Chalon sur Saone , , France
Local Institute
La Roche sur Yon , , France
Local Institution
La Roche-sur-yon Cedex 9 , 85925, France
Local Institution
Limoges , 87042, France
Local Institute
Limoges , , France
Local Institution
Meaux , 77100, France
Local Institute
Meaux , , France
Local Institution
Nantes , 44093, France
Local Institute
Nantes , , France
Local Institution
Perigueux , 24000, France
Local Institute
Rennes , 35033, France
Local Institution
Rennes , 35033, France
Local Institute
Heidelberg Baden-Württemberg, 69120, Germany
Local Institute
Hamm Nordrhein-Westfalen, 59071, Germany
Local Institute
Aschaffenburg , 63739, Germany
Local Institution
Aschaffenburg , 63739, Germany
Local Institute
Berlin , 10407, Germany
Local Institution
Berlin , 10407, Germany
Local Institution
Bielefeld , 33611, Germany
Local Institution
Bochum , 44787, Germany
Local Institute
Dresden , 01099, Germany
Local Institution
Dresden , 01307, Germany
Local Institution
Frankfurt-oder , 15236, Germany
Local Institution
Gelsenkirchen , 45879, Germany
Local Institution
Goslar , 38642, Germany
Local Institution
Hamm , 59071, Germany
Local Institution - 0071
Heidelberg , 69120, Germany
Local Institution
Kiel , 24116, Germany
Local Institution
Köln , 50674, Germany
Local Institution - 0076
Ludwigsburg , 71640, Germany
Local Institute
Magdeburg , 39104, Germany
Local Institution
Magdeburg , 39104, Germany
Local Institution
Muenchen , 81377, Germany
Local Institution - 0079
Mutlangen , 73557, Germany
Local Institute
München , , Germany
Local Institution
Oldenburg , 26121, Germany
Local Institution
Reutlingen , 72764, Germany
Local Institution
Rostock , 18057, Germany
Local Institution
Rostock , 18059, Germany
Local Institute
Rostock , , Germany
Local Institution
Traunstein , 83278, Germany
Local Institution
Wiesbaden , 65191, Germany
Local Institute
Pesaro Pesaro E Urbino, 61122, Italy
Local Institute
Ancona , 04200, Italy
Local Institution
Ancona , 60123, Italy
Local Institute
Ancona , 60126, Italy
Local Institution
Cagliari , 09121, Italy
Local Institute
Cagliari , B354, Italy
Local Institution
Firenze , 50134, Italy
Local Institute
Firenze , 50139, Italy
Local Institute
Lecce , 73100, Italy
Local Institution - 0113
Lecce , 73100, Italy
Local Institution
Messina , 98121, Italy
Local Institution
Messina , 98122, Italy
Local Institute
Milano , 20121, Italy
Local Institution
Milano , 20133, Italy
Local Institute
Napoli , 80136, Italy
Local Institution
Napoli , 80139, Italy
Local Institution
Pesaro , 61122, Italy
Local Institution
Pescara , 65124, Italy
Local Institute
Roma , 00161, Italy
Local Institution
Roma , 00161, Italy
Local Institution
Roma , 00189, Italy
Local Institution
Roma , 00189, Italy
Local Institution
San Giovanni Rotondo (FG) , 71013, Italy
Local Institution
Terni , 05100, Italy
Local Institute
Terni , 5100, Italy
Local Institute
Torino , 10126, Italy
Local Institution
Torino , 10126, Italy
Local Institute
Vicenza , 36100, Italy
Local Institution
Vicenza , 36100, Italy
Local Institute
Truro Cornwall, TR1 3, United Kingdom
Local Institution
Harrow , HA1 3, United Kingdom
Local Institute
Leeds , LS9 7, United Kingdom
Local Institution - 0092
Leeds , LS97T, United Kingdom
Local Institution
Liverpool , L7 8X, United Kingdom
Local Institution
Liverpool , L7 8X, United Kingdom
Local Institution
Manchester , 30115, United Kingdom
Local Institute
Nottingham , NG5 1, United Kingdom
Local Institution
Nottingham , NG5 1, United Kingdom
Local Institute
Stafford , ST16 , United Kingdom
Local Institution
Stafford , ST16 , United Kingdom
Local Institute
Swansea , SA2 8, United Kingdom
Local Institution
Swansea , SA2 8, United Kingdom
Local Institution
Truro , TR1 3, United Kingdom

How clear is this clinincal trial information?

Study is for people with:

Multiple Myeloma

Estimated Enrollment:

2555

Study ID:

NCT01838512

Recruitment Status:

Recruiting

Sponsor:


Bristol-Myers Squibb

How clear is this clinincal trial information?

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