Multiple Sclerosis Clinical Trial

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Anti-Inflammatory Type II Monocyte Induction by Glatiramer Acetate (Copaxone) Treatment of Multiple Sclerosis

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Summary

The purpose of this study is to determine whether glatiramer acetate (Copaxone) will induce anti-inflammatory type II monocyte development during treatment of MS, and if these antigen presenting cells (APC) will promote Th2 and Treg differentiation of naïve T cells.

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Eligibility Criteria

Inclusion Criteria:

Relapsing-remitting (RR) MS patients (McDonald criteria)
Ages 18-55
Males and females
EDSS score ≤5
No prior treatment with Copaxone
Prior treatment with corticosteroids or interferon-beta (-1a or -1b) is acceptable, provided there is a washout period of at least one month

Exclusion Criteria:

Treatment with Tysabri, Novantrone or cyclophosphamide
Treatment with other immunomodulatory therapies (e.g. imuran, mycophenolate or methotrexate)
Primary-progressive (PP) and secondary-progressive (SP) multiple sclerosis
Pregnancy

Study is for people with:

Multiple Sclerosis

Estimated Enrollment:

17

Study ID:

NCT00819195

Recruitment Status:

Completed

Sponsor:

University of California, San Francisco

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There is 1 Location for this study

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UCSF Multiple Sclerosis Center
San Francisco California, 94143, United States

How clear is this clinincal trial information?

Study is for people with:

Multiple Sclerosis

Estimated Enrollment:

17

Study ID:

NCT00819195

Recruitment Status:

Completed

Sponsor:


University of California, San Francisco

How clear is this clinincal trial information?

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