Multiple Sclerosis Clinical Trial
Clinical Study to Evaluate the Efficacy, Safety, and Tolerability of ACT-128800 in Patients With Relapsing-remitting Multiple Sclerosis
Summary
This study will assess the efficacy, safety, and tolerability of ACT-128800 in patients with relapsing-remitting multiple sclerosis.
Eligibility Criteria
Inclusion Criteria:
Adult males and females
Diagnosis of RRMS as defined by the revised (2005) McDonald Diagnostic Criteria for Multiple Sclerosis (MS).
Signed inform consent prior to initiation of any study-mandated procedure.
Exclusion Criteria:
A diagnosis of MS categorized as primary progressive or secondary progressive or progressive relapsing.
Patients currently treated for an autoimmune disorder other than MS.
Contraindications for MRI.
Ongoing bacterial, viral, or fungal infection.
History or presence of malignancy.
Additional inclusion and exclusion criteria apply with respect to medical conditions and concomitant treatments which could affect patients' risk from participating in the study.
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There are 112 Locations for this study
Scottsdale Arizona, 85259, United States
Tucson Arizona, 85741, United States
Sacramento California, 95817, United States
Stanford California, 94305, United States
Sarasota Florida, 34233, United States
Indianapolis Indiana, 46202, United States
Kansas City Kansas, 66160, United States
Lenexa Kansas, 66214, United States
Baltimore Maryland, 21201, United States
Worcester Massachusetts, 01605, United States
Saint Louis Missouri, 63100, United States
Newark New Jersey, 07103, United States
Latham New York, 12110, United States
New York New York, 10032, United States
Schenectady New York, 12308, United States
Stony Brook New York, 11794, United States
Raleigh North Carolina, 27607, United States
Akron Ohio, 44320, United States
Cincinnati Ohio, 45219, United States
Columbus Ohio, 43221, United States
Portland Oregon, 97225, United States
Philadelphia Pennsylvania, 19107, United States
Burlington Vermont, 05401, United States
Richmond Virginia, 23298, United States
Kirkland Washington, 98034, United States
Fitzroy , 3065, Australia
Westmead , 2145, Australia
Amstetten , 3300, Austria
St Polten , 3100, Austria
Vienna , 1090, Austria
La Louviere , 7100, Belgium
Liege , 4000, Belgium
Ottignies , 1340, Belgium
Sijsele-Damme , 8340, Belgium
Sofia , 1309, Bulgaria
Sofia , 1431, Bulgaria
Varna , 9010, Bulgaria
Varna , 9010, Bulgaria
Burbaby British Columbia, V5G 2, Canada
Burnaby , V5G 2, Canada
Ottawa , K1H 8, Canada
Brno , 656 9, Czechia
Jihlava , 586 3, Czechia
Olomouc , 775 2, Czechia
Ostrava-Poruba , 70852, Czechia
Praha , 128 0, Czechia
Teplice , , Czechia
Helsinki , 00100, Finland
Hyvinkaa , 05800, Finland
Tampere , 33520, Finland
Turku , 20100, Finland
Montpellier Cedex , 34295, France
Bayreuth , 95445, Germany
Berlin , 10117, Germany
Berlin , 13347, Germany
Dusseldorf , 40225, Germany
Essen , 45147, Germany
Homburg/Saar , 66421, Germany
Ulm , 89081, Germany
Budapest , 1134, Hungary
Budapest , H-111, Hungary
Budapest , H-114, Hungary
Gyor , 11-90, Hungary
Petofi , 2500, Hungary
Szentpeteri-Kapu , 3526, Hungary
Ashkelon , 78278, Israel
Tel-Aviv , 64239, Israel
Tel-Hashomer , 52621, Israel
Zerifin , 70300, Israel
Gallarte , 21013, Italy
Genova , 16132, Italy
Milan , 20132, Italy
Padova , 35128, Italy
Roma , 00189, Italy
Siena , 53100, Italy
Breda , 4818, Netherlands
Nijmegen , 6533, Netherlands
Sittard-Geleen , 6162, Netherlands
Katowice , 47-75, Poland
Poznan , 60-35, Poland
Warsaw , 02-95, Poland
Wroclaw , 50-04, Poland
Bucuresti , 02290, Romania
Cluj-Napoca , 42806, Romania
Timisoara , 30073, Romania
Moscow , 12701, Russian Federation
Nizhniy Novgorod , 60315, Russian Federation
Pyatigorsk , 35753, Russian Federation
Samara , 44309, Russian Federation
Saratov , 41003, Russian Federation
St. Petersburg , 19435, Russian Federation
St. Petersburg , 19702, Russian Federation
St. Petersburg , 19737, Russian Federation
Ufa , 45000, Russian Federation
Belgrade , 11000, Serbia
Kragujevac , 34000, Serbia
Nis , 18000, Serbia
Barcelona , 08035, Spain
Madrid , 28040, Spain
Madrid , 28222, Spain
Malaga , 29010, Spain
Sevilla , 41009, Spain
Valencia , 46009, Spain
Goteburg , 41345, Sweden
Stockholm , 17176, Sweden
Umed , 90185, Sweden
Lugano , CH-69, Switzerland
St Gallen , CH-90, Switzerland
Chernihiv , 14029, Ukraine
Dnipropetrovsk , 49044, Ukraine
Kyiv , 03110, Ukraine
Odesa , 65000, Ukraine
Bristol , BS16 , United Kingdom
Devon , PL6 S, United Kingdom
London , SE5 9, United Kingdom
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