Multiple Sclerosis Clinical Trial
Improving Prospective Memory Via Telehealth
Summary
Up to 70% of persons with multiple sclerosis (PwMS) experience cognitive impairment, which can have a significant impact on several aspects of their daily lives. One cognitive domain that has been shown to impact daily functioning, but is understudied in MS, is prospective memory (PM). While there have been successful PM interventions in other clinical populations, to date there has not been a specific PM intervention for PwMS that has been tested in a clinical trial.
The study will be a double-masked randomized feasibility trial, with 18 participants randomized to a PM intervention and 18 participants randomized to an active control (psychoeducation). Participants will meet with an interventionist twice a week for four weeks. Feasibility will be assessed via 1) recruitment, enrollment, and retention; 2) adherence to the treatment; 3) treatment credibility and expectancy; and 4) treatment satisfaction. A preliminary effect size (Cohen's d) will be computed for the group difference using participants' performance on the Memory for Intentions Test, which will be given at baseline (week 1) and post-treatment (week 6). Participants will also complete a battery of neuropsychological measures as part of their baseline and post-treatment assessments.
Eligibility Criteria
Inclusion Criteria:
Clinical diagnosis of MS
Able to read, write, and speak in English
Between the ages of 18 and 60
All genders
No history of other serious neurologic or psychiatric illness, including drug or alcohol misuse
No relapses within the past two months
Access to the Internet and a web camera
Not enrolled in a cognitive rehabilitation program within the past six months
Self-reported issues "remembering places they have to be" and "things they have to do"
Exclusion Criteria:
No diagnosis of MS
Unable to complete the study protocol due to language barriers
Younger than 18 or older than 61
No gender exclusions
History of other serious neurologic or psychiatric illness, including drug or alcohol misuse
Had a relapse within the past two months
No access to the Internet and/or a web camera
Currently enrolled or enrolled in a cognitive rehabilitation program within the past six months
No self-reported issues with "remembering places they have to be" or "things they have to do"
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There is 1 Location for this study
Hartford Connecticut, 06112, United States
How clear is this clinincal trial information?

Please confirm you are a US based health care provider:
Yes, I am a health care Provider No, I am not a health care providerSign Up Now.
Take Control of Your Disease Journey.
Sign up now for expert patient guides, personalized treatment options, and cutting-edge insights that can help you push for the best care plan.