Multiple Sclerosis Clinical Trial

Longitudinal Cortical Demyelination in Multiple Sclerosis and Related Disorders

Summary

In this protocol, a combination of MRI, blood, and cerebrospinal fluid (CSF) analysis will be used to understand the natural history, underlying immunologic mechanisms, and clinical implications of central nervous system (CNS) lesions, in particular lesions in the cerebral cortex, in multiple sclerosis (MS) and other inflammatory and autoimmune disorders affecting the CNS. Patients with these disorders, as well as healthy controls, will undergo baseline clinical evaluation and testing, bloodwork, and MRI, with follow up clinical evaluation, bloodwork, and MRI at years 1, 3, and 6. Additional MRIs may be performed in patients with possible new lesion formation or to compare MRI techniques. Lumbar puncture will be performed on participants who are not currently being treated with disease modifying therapies and who are willing to undergo the procedure.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

18 years old
able to provide consent in English
able to undergo MRI

Exclusion Criteria:

contraindication to MRI
pregnancy

Study is for people with:

Multiple Sclerosis

Estimated Enrollment:

100

Study ID:

NCT05982925

Recruitment Status:

Recruiting

Sponsor:

Icahn School of Medicine at Mount Sinai

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There is 1 Location for this study

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Mount Sinai Hospital
New York New York, 10029, United States More Info
Erin S Beck, MD, PhD
Contact
212-241-2474
[email protected]
Julia L Galasso, BS
Contact
212-241-9463
[email protected]
Erin S Beck
Principal Investigator

How clear is this clinincal trial information?

Study is for people with:

Multiple Sclerosis

Estimated Enrollment:

100

Study ID:

NCT05982925

Recruitment Status:

Recruiting

Sponsor:


Icahn School of Medicine at Mount Sinai

How clear is this clinincal trial information?

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