Multiple Sclerosis Clinical Trial
The Longitudinal CONQUER Study of Rare Neuroimmunologic Disorders
Summary
This study seeks to determine the biologic causes of inflammation in patients with Transverse Myelitis (TM) Neuromyelitis Optica Spectrum Disorder (NMOSD) and related conditions. While patients will be treated according to decisions with their treating physician, this study will collect data and samples from patients prospectively to gain a better understanding of the disease. We are seeking to understand why some patients respond to medications, while others do not. We also seek to understand what happens biologically, preceding relapses. Gathering these data and samples will allow researchers to identify new ways of diagnosing and treating these diseases. Data and samples will be shared with researchers around the world to support collaborative efforts to treat these conditions.
Full Description
This study seeks to determine the biologic causes of inflammation in patients with Neuromyelitis Optica (NMO), Transverse Myelitis (TM), optic neuritis (ON), related conditions and healthy controls. While patients will be treated according to decisions with their treating physician, this study will collect data and samples from patients prospectively to gain a better understanding of the disease. We are seeking to understand why some patients respond to medications, while others do not. We also seek to understand what happens biologically, preceding relapses. Gathering these data and samples will allow researchers to identify new ways of diagnosing and treating these diseases. Data and samples will be shared with researchers around the world to support collaborative efforts to treat these conditions.
Patients will agree to share medical records, complete questionnaires and donate samples on a timed basis.
Eligibility Criteria
Inclusion Criteria:
Age 6 years or greater
Male or Female
Patient or Parent (in the case of a minor) able to give informed consent
For patients 10 to 17, patient able to assent
Patient diagnosed with NMO, NMOSD, TM or ON
Exclusion Criteria:
Unable to maintain scheduled visits
Patient has known HIV or hepatitis C infection
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There is 1 Location for this study
Dallas Texas, 75390, United States More Info
Principal Investigator
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