Myelodysplastic Syndrome Clinical Trial

Collecting and Storing Blood, Bone Marrow, and Other Samples From Patients With Acute Leukemia, Chronic Leukemia, or Myelodysplastic Syndromes

Summary

As one of the nation's largest cooperative cancer treatment groups, the Alliance for Clinical Trials in Oncology (Alliance) is in a unique position to organize a Leukemia Tissue Bank. The member institutions diagnose hundreds of patients with leukemia or myelodysplastic syndrome each year, and uniformly treat these patients with chemotherapy regimens. The Alliance offers centralized data management for the clinical history, the classification of the leukemia and myelodysplastic syndrome, cytogenetics, flow cytometric analysis, treatment and follow-up. The highly skilled health care providers at each member institution are familiar with obtaining informed consent, completing data questionnaires and shipping specimens. There currently exists a central processing facility where samples are prepared for a variety of cellular and molecular studies. Hence, the patient resources, the health care providers, and a processing facility for a Leukemia Tissue Bank are all in place. What is needed, however, and is addressed in the current protocol, is a formal mechanism to procure bone marrow, blood and normal tissue from patients with hematologic malignancies who are to be enrolled on Alliance (Cancer and Leukemia Group B [CALGB]) treatment studies.

View Full Description

Full Description

The objective of the study is to collect and store specimens from every newly diagnosed patient with acute or chronic leukemia or myelodysplastic syndrome (MDS) who are entered on a CALGB protocol for previously untreated patients. Bone marrow aspirate and blood specimens are obtained from patients at diagnosis, remission, or relapse and stored. Buccal smears are obtained at diagnosis, and DNA is extracted and preserved.

It was anticipated that the specimens collected under this protocol would be used by a large number of investigators. This protocol does not describe the details of each approved project (eg, eligibility age range).

View Eligibility Criteria

Eligibility Criteria

Previously untreated patients on a CALGB treatment protocol for leukemia (acute or chronic) or myelodysplasia are eligible. Patients must be registered to CALGB 9665 prior to receiving any therapy for their disease.
Signed informed consent

Study is for people with:

Myelodysplastic Syndrome

Estimated Enrollment:

1500

Study ID:

NCT00899223

Recruitment Status:

Active, not recruiting

Sponsor:

Alliance for Clinical Trials in Oncology

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There are 124 Locations for this study

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Camino Medical Group - Treatment Center
Mountain View California, 94040, United States

Pismo Beach California, 93449, United States
Naval Medical Center - San Diego
San Diego California, 92134, United States
UCSF Helen Diller Family Comprehensive Cancer Center
San Francisco California, 94115, United States
Helen and Harry Gray Cancer Center at Hartford Hospital
Hartford Connecticut, 06102, United States
Tunnell Cancer Center at Beebe Medical Center
Lewes Delaware, 19958, United States
CCOP - Christiana Care Health Services
Newark Delaware, 19713, United States
Lombardi Comprehensive Cancer Center at Georgetown University Medical Center
Washington District of Columbia, 20007, United States
Washington Cancer Institute at Washington Hospital Center
Washington District of Columbia, 20010, United States
Michael and Dianne Bienes Comprehensive Cancer Center at Holy Cross Hospital
Fort Lauderdale Florida, 33308, United States
Ella Milbank Foshay Cancer Center at Jupiter Medical Center
Jupiter Florida, 33458, United States
CCOP - Mount Sinai Medical Center
Miami Beach Florida, 33140, United States
Florida Hospital Cancer Institute at Florida Hospital Orlando
Orlando Florida, 32803, United States
Illinois CancerCare - Bloomington
Bloomington Illinois, 61701, United States
St. Joseph Medical Center
Bloomington Illinois, 61701, United States
Illinois CancerCare - Canton
Canton Illinois, 61520, United States
University of Illinois Cancer Center
Chicago Illinois, 60612, United States
Veterans Affairs Medical Center - Chicago Westside Hospital
Chicago Illinois, 60612, United States
University of Chicago Cancer Research Center
Chicago Illinois, 60637, United States
Eureka Community Hospital
Eureka Illinois, 61530, United States
Illinois CancerCare - Eureka
Eureka Illinois, 61530, United States
Evanston Hospital
Evanston Illinois, 60201, United States
Galesburg Clinic, PC
Galesburg Illinois, 61401, United States
Illinois CancerCare - Macomb
Macomb Illinois, 61455, United States
BroMenn Regional Medical Center
Normal Illinois, 61761, United States
Community Cancer Center
Normal Illinois, 61761, United States
Illinois CancerCare - Community Cancer Center
Normal Illinois, 61761, United States
Community Hospital of Ottawa
Ottawa Illinois, 61350, United States
Oncology Hematology Associates of Central Illinois, PC - Ottawa
Ottawa Illinois, 61350, United States
Cancer Treatment Center at Pekin Hospital
Pekin Illinois, 61554, United States
Illinois CancerCare - Pekin
Pekin Illinois, 61603, United States
Proctor Hospital
Peoria Illinois, 61614, United States
CCOP - Illinois Oncology Research Association
Peoria Illinois, 61615, United States
Oncology Hematology Associates of Central Illinois, PC - Peoria
Peoria Illinois, 61615, United States
Methodist Medical Center of Illinois
Peoria Illinois, 61636, United States
OSF St. Francis Medical Center
Peoria Illinois, 61637, United States
Illinois CancerCare - Peru
Peru Illinois, 61354, United States
Illinois Valley Community Hospital
Peru Illinois, 61354, United States
Illinois CancerCare - Spring Valley
Spring Valley Illinois, 61362, United States
Elkhart Clinic, LLC
Elkhart Indiana, 46514, United States
Michiana Hematology-Oncology, PC - Elkhart
Elkhart Indiana, 46514, United States
Elkhart General Hospital
Elkhart Indiana, 46515, United States
Howard Community Hospital
Kokomo Indiana, 46904, United States
Center for Cancer Therapy at LaPorte Hospital and Health Services
La Porte Indiana, 46350, United States
Suniti Medical Corporation
Merrillville Indiana, 46410, United States
Michiana Hematology-Oncology, PC - South Bend
Mishawaka Indiana, 46545, United States
Saint Joseph Regional Medical Center
Mishawaka Indiana, 46545, United States
Michiana Hematology Oncology PC - Plymouth
Plymouth Indiana, 46563, United States
CCOP - Northern Indiana CR Consortium
South Bend Indiana, 46601, United States
Memorial Hospital of South Bend
South Bend Indiana, 46601, United States
Michiana Hematology Oncology PC - La Porte
Westville Indiana, 46391, United States
Hematology Oncology Associates of the Quad Cities
Bettendorf Iowa, 52722, United States
Iowa Blood and Cancer Care
Cedar Rapids Iowa, 52402, United States
Holden Comprehensive Cancer Center at University of Iowa
Iowa City Iowa, 52242, United States
Veterans Affairs Medical Center - Iowa City
Iowa City Iowa, 52246, United States
Menorah Medical Center
Overland Park Kansas, 66209, United States
Saint Luke's Hospital - South
Overland Park Kansas, 66213, United States
CCOP - Kansas City
Prairie Village Kansas, 66208, United States
Harold Alfond Center for Cancer Care
Augusta Maine, 04330, United States
CancerCare of Maine at Eastern Maine Medical Center
Bangor Maine, 04401, United States
Greenebaum Cancer Center at University of Maryland Medical Center
Baltimore Maryland, 21201, United States
National Naval Medical Center
Bethesda Maryland, 20889, United States
Union Hospital of Cecil County
Elkton Maryland, 21921, United States
Massachusetts General Hospital
Boston Massachusetts, 02114, United States
Dana-Farber/Brigham and Women's Cancer Center
Boston Massachusetts, 02115, United States
Dana-Farber/Harvard Cancer Center at Dana-Farber Cancer Institute
Boston Massachusetts, 02115, United States
Addison Gilbert Hospital
Gloucester Massachusetts, 01930, United States
Lakeland Regional Cancer Care Center - St. Joseph
Saint Joseph Michigan, 49085, United States
Lakeside Cancer Specialists, PLLC
Saint Joseph Michigan, 49085, United States
St. Luke's Hospital Cancer Care Center
Duluth Minnesota, 55805, United States
Veterans Affairs Medical Center - Minneapolis
Minneapolis Minnesota, 55417, United States
Masonic Cancer Center at University of Minnesota
Minneapolis Minnesota, 55455, United States
Southeast Cancer Center
Cape Girardeau Missouri, 63703, United States
Ellis Fischel Cancer Center at University of Missouri - Columbia
Columbia Missouri, 65203, United States
Goldschmidt Cancer Center
Jefferson City Missouri, 65109, United States
Saint Luke's Cancer Institute at Saint Luke's Hospital
Kansas City Missouri, 64111, United States
North Kansas City Hospital
Kansas City Missouri, 64116, United States
Heartland Hematology Oncology Associates, Incorporated
Kansas City Missouri, 64118, United States
Research Medical Center
Kansas City Missouri, 64132, United States
Saint Luke's East - Lee's Summit
Lee's Summit Missouri, 64086, United States
Saint Joseph Oncology, Incorporated
Saint Joseph Missouri, 64507, United States
Siteman Cancer Center at Barnes-Jewish Hospital - Saint Louis
Saint Louis Missouri, 63110, United States
Missouri Baptist Cancer Center
Saint Louis Missouri, 63131, United States
Saint Francis Cancer Treatment Center at Saint Francis Memorial Health Center
Grand Island Nebraska, 68803, United States
Callahan Cancer Center at Great Plains Regional Medical Center
North Platte Nebraska, 69103, United States
UNMC Eppley Cancer Center at the University of Nebraska Medical Center
Omaha Nebraska, 68198, United States
University Medical Center of Southern Nevada
Las Vegas Nevada, 89102, United States
CCOP - Nevada Cancer Research Foundation
Las Vegas Nevada, 89106, United States
Sunrise Hospital and Medical Center
Las Vegas Nevada, 89109, United States
New Hampshire Oncology - Hematology, PA at Payson Center for Cancer Care
Concord New Hampshire, 03301, United States
New Hampshire Oncology - Hematology, PA - Hooksett
Hooksett New Hampshire, 03106, United States
Lakes Region General Hospital
Laconia New Hampshire, 03246, United States
Norris Cotton Cancer Center at Dartmouth-Hitchcock Medical Center
Lebanon New Hampshire, 03756, United States
Norris Cotton Cancer Center at Catholic Medical Center
Manchester New Hampshire, 03102, United States
Cancer Institute of New Jersey at Cooper - Voorhees
Voorhees New Jersey, 08043, United States
Roswell Park Cancer Institute
Buffalo New York, 14263, United States
CCOP - Hematology-Oncology Associates of Central New York
East Syracuse New York, 13057, United States
Charles R. Wood Cancer Center at Glens Falls Hospital
Glens Falls New York, 12801, United States
Queens Cancer Center of Queens Hospital
Jamaica New York, 11432, United States
Monter Cancer Center of the North Shore-LIJ Health System
Lake Success New York, 11042, United States
CCOP - North Shore University Hospital
Manhasset New York, 11030, United States
Don Monti Comprehensive Cancer Center at North Shore University Hospital
Manhasset New York, 11030, United States
Long Island Jewish Medical Center
New Hyde Park New York, 11040, United States
New York Weill Cornell Cancer Center at Cornell University
New York New York, 10021, United States
Mount Sinai Medical Center
New York New York, 10029, United States
SUNY Upstate Medical University Hospital
Syracuse New York, 13210, United States
Veterans Affairs Medical Center - Syracuse
Syracuse New York, 13210, United States
Mission Hospitals - Memorial Campus
Asheville North Carolina, 28801, United States
Lineberger Comprehensive Cancer Center at University of North Carolina - Chapel Hill
Chapel Hill North Carolina, 27599, United States
Blumenthal Cancer Center at Carolinas Medical Center
Charlotte North Carolina, 28232, United States
Presbyterian Cancer Center at Presbyterian Hospital
Charlotte North Carolina, 28233, United States
Batte Cancer Center at Northeast Medical Center
Concord North Carolina, 28025, United States
Duke Cancer Institute
Durham North Carolina, 27710, United States
Wayne Memorial Hospital, Incorporated
Goldsboro North Carolina, 27534, United States
Leo W. Jenkins Cancer Center at ECU Medical School
Greenville North Carolina, 27834, United States
Pardee Memorial Hospital
Hendersonville North Carolina, 28791, United States
Kinston Medical Specialists
Kinston North Carolina, 28501, United States
Cleveland Regional Medical Center
Shelby North Carolina, 28150, United States
Iredell Memorial Hospital
Statesville North Carolina, 28677, United States
Forsyth Regional Cancer Center at Forsyth Medical Center
Winston-Salem North Carolina, 27103, United States
Wake Forest University Comprehensive Cancer Center
Winston-Salem North Carolina, 27157, United States
Arthur G. James Cancer Hospital and Richard J. Solove Research Institute at Ohio State University Comprehensive Cancer Center
Columbus Ohio, 43210, United States
Cancer Care Associates - Norman
Norman Oklahoma, 73071, United States
Oklahoma University Cancer Institute
Oklahoma City Oklahoma, 73104, United States
Cancer Care Associates - Mercy Campus
Oklahoma City Oklahoma, 73120, United States
Western Pennsylvania Cancer Institute at Western Pennsylvania Hospital
Pittsburgh Pennsylvania, 15224, United States
Rhode Island Hospital Comprehensive Cancer Center
Providence Rhode Island, 02903, United States
Miriam Hospital
Providence Rhode Island, 02906, United States
McLeod Regional Medical Center
Florence South Carolina, 29501, United States
Cancer Centers of the Carolinas - Faris Road
Greenville South Carolina, 29605, United States
Cancer Centers of the Carolinas - Grove Commons
Greenville South Carolina, 29605, United States
Greenville Hospital Cancer Center
Greenville South Carolina, 29605, United States
Cancer Centers of the Carolinas - Eastside
Greenville South Carolina, 29615, United States
CCOP - Greenville
Greenville South Carolina, 29615, United States
Cancer Centers of the Carolinas - Greer Medical Oncology
Greer South Carolina, 29650, United States
Cancer Centers of the Carolinas - Seneca
Seneca South Carolina, 29672, United States
Cancer Centers of the Carolinas - Spartanburg
Spartanburg South Carolina, 29307, United States
Mountainview Medical
Berlin Vermont, 05602, United States
Fletcher Allen Health Care - University Health Center Campus
Burlington Vermont, 05401, United States
Danville Regional Medical Center
Danville Virginia, 24541, United States
Ravenel Oncology Center at Memorial Hospital of Martinsville and Henry County
Martinsville Virginia, 24115, United States
Virginia Commonwealth University Massey Cancer Center
Richmond Virginia, 23298, United States

How clear is this clinincal trial information?

Study is for people with:

Myelodysplastic Syndrome

Estimated Enrollment:

1500

Study ID:

NCT00899223

Recruitment Status:

Active, not recruiting

Sponsor:


Alliance for Clinical Trials in Oncology

How clear is this clinincal trial information?

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