Myeloproliferative Neoplasms Clinical Trial

A Long-Term Study of the Effects of Orally Administered SAR302503 in Patients With Myelofibrosis

Summary

The purpose of this study is to evaluate the long-term effects of orally administered SAR302503 (TG101348) in patients with myelofibrosis who have completed the MF-TG101348-001 study.

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Full Description

SAR302503 (TG101348) is a potent small molecule inhibitor of Janus kinase 2 (JAK2). This is an extension study for a first-in-man, dose escalation study (MF-TG101348-001). The safety, tolerability and clinical activity of SAR302503 (TG101348) in subjects with myelofibrosis will be evaluated.

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Eligibility Criteria

Inclusion Criteria:

Completion of MF-TG101348-001 study
Diagnosis of myelofibrosis
At least 18 years of age

Exclusion Criteria:

Any acute or chronic medical abnormality that may increase the risk associated with study participation

Study is for people with:

Myeloproliferative Neoplasms

Phase:

Phase 1

Estimated Enrollment:

42

Study ID:

NCT00724334

Recruitment Status:

Completed

Sponsor:

Sanofi

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There are 6 Locations for this study

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Investigational Site Number 840103
La Jolla California, 92093, United States
Investigational Site Number 840102
Stanford California, 94305, United States
Investigational Site Number 840105
Boston Massachusetts, 02115, United States
Investigational Site Number 840106
Ann Arbor Michigan, 48109, United States
Investigational Site Number 840104
Rochester Minnesota, 55905, United States
Investigational Site Number 840101
Houston Texas, 77030, United States

How clear is this clinincal trial information?

Study is for people with:

Myeloproliferative Neoplasms

Phase:

Phase 1

Estimated Enrollment:

42

Study ID:

NCT00724334

Recruitment Status:

Completed

Sponsor:


Sanofi

How clear is this clinincal trial information?

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