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A Long-Term Study of the Effects of Orally Administered SAR302503 in Patients With Myelofibrosis Summary The purpose of this study is to evaluate the long-term effects of orally administered SAR302503 (TG101348) in patients with myelofibrosis who have completed the MF-TG101348-001 study.
View Full Description Full Description SAR302503 (TG101348) is a potent small molecule inhibitor of Janus kinase 2 (JAK2). This is an extension study for a first-in-man, dose escalation study (MF-TG101348-001). The safety, tolerability and clinical activity of SAR302503 (TG101348) in subjects with myelofibrosis will be evaluated.
View Eligibility Criteria Eligibility Criteria Inclusion Criteria: Completion of MF-TG101348-001 study Diagnosis of myelofibrosis At least 18 years of age Exclusion Criteria: Any acute or chronic medical abnormality that may increase the risk associated with study participation
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There are 6 Locations for this study
Investigational Site Number 840103 La Jolla California, 92093, United States
Investigational Site Number 840102 Stanford California, 94305, United States
Investigational Site Number 840105 Boston Massachusetts, 02115, United States
Investigational Site Number 840106 Ann Arbor Michigan, 48109, United States
Investigational Site Number 840104 Rochester Minnesota, 55905, United States
Investigational Site Number 840101 Houston Texas, 77030, United States
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