Non Hodgkin Lymphoma Clinical Trial
Safety and Efficacy of IDEC-114 in Combination With Rituxan in the Treatment of Non-Hodgkin’s Lymphoma
Summary
To determine what side effects and what clinical effect, if any, the administration of this investigational product, IDEC-114 in combination with Rituxan® [Rituxan® as a single agent is approved by the United States Food and Drug Administration (FDA) to treat patients with relapsed or refractory follicular NHL], has in this patient population.
Eligibility Criteria
Inclusion Criteria:
Signed IRB-approved informed consent
Greater than or equal to 18 years of age
Proof of follicular lymphoma
Progressive disease requiring treatment after at least 1 prior standard therapy
Acceptable hematologic status, liver function, and renal function
Patients of reproductive potential must agree to follow accepted birth control methods during treatment and for 3 months after completion of treatment
Exclusion Criteria:
No response to prior Rituxan® or Rituxan®-containing regimen
Presence of CLL or CNS lymphoma
Known history of HIV infection or AIDS
Prior diagnosis of aggressive NHL or mantle-cell lymphoma
Serious nonmalignant disease
Pregnant or currently breast feeding
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There are 22 Locations for this study
Birmingham Alabama, 35294, United States
Tucson Arizona, 85724, United States
Los Angeles California, 90095, United States
Newport Beach California, 92658, United States
San Diego California, 92121, United States
Aurora Colorado, 80010, United States
Washington District of Columbia, 20007, United States
Tampa Bay Florida, 33612, United States
Chicago Illinois, 60611, United States
Maywood Illinois, 60153, United States
Boston Massachusetts, 2115, United States
Detroit, Michigan, 48202, United States
Rochester Minnesota, 55905, United States
Omaha Nebraska, 68198, United States
Buffalo New York, 14263, United States
New York New York, 10021, United States
Rochester New York, 14642, United States
Durham North Carolina, 27710, United States
Philadelphia Pennsylvania, 1906, United States
Columbia South Carolina, 29210, United States
Houston Texas, 77030, United States
Charlottesville Virginia, 22908, United States
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