Non Hodgkin Lymphoma Clinical Trial
Study of Nivolumab in Patients With Classical Hodgkin’s Lymphoma (Registrational)
Summary
The purpose of this study is to evaluate the efficacy and safety of Nivolumab in previously treated (cohorts, A, B & C) or newly diagnosed (cohort D) classical Hodgkin Lymphoma participants.
Eligibility Criteria
Inclusion Criteria:
Eastern Cooperative Oncology Group (ECOG) performance status 0 or 1
Must have received prior high-dose conditioning chemotherapy followed by autologous stem cell transplant (ASCT) as a part of salvage therapy for cHL (cohort A, B & C - enrollment closed)
Participants may be Brentuximab vedotin- naïve, or may have had prior Brentuximab vedotin treatment (cohort A, B & C - enrollment closed)
Newly diagnosed and previously untreated classical Hodgkin Lymphoma (cohort D)
Exclusion Criteria:
Known central nervous system lymphoma
Participants with nodular lymphocyte-predominant Hodgkin Lymphoma
Prior allogeneic stem cell transplantation (SCT)
Chest radiation ≤ 24 weeks prior to first dose
Carmustine ≥ 600 mg/m² received as part of the pre-transplant conditioning regimen
Check Your Eligibility
Let’s see if you might be eligible for this study.
What is your age and gender ?
There are 36 Locations for this study
Los Angeles California, 90048, United States
Los Angeles California, 90095, United States
Atlanta Georgia, 30322, United States
Boston Massachusetts, 02215, United States
Boston Massachusetts, 02215, United States
Boston Massachusetts, 02215, United States
Detroit Michigan, 48201, United States
Rochester Minnesota, 55905, United States
Basking Ridge New Jersey, 07920, United States
Hackensack New Jersey, 07601, United States
New York New York, 10021, United States
Allentown Pennsylvania, 18103, United States
Nashville Tennessee, 37232, United States
Houston Texas, 77030, United States
Innsbruck , 6020, Austria
Wien , 1090, Austria
B-leuven , 3000, Belgium
Gent , 9000, Belgium
Vancouver British Columbia, V5Z 4, Canada
Toronto Ontario, M5G 2, Canada
Praha 2 , 128 0, Czechia
Berlin , 10117, Germany
Hamburg , 20099, Germany
Koeln , 50937, Germany
Ulm , 89081, Germany
Bologna , 40126, Italy
Napoli , 80131, Italy
Rozzano (milano) , 20089, Italy
Amsterdam , 1066 , Netherlands
Groningen , 9713 , Netherlands
Utrecht , 3584 , Netherlands
Hospitalet Llobregat- Barcelona , 9908, Spain
Majadahonda - Madrid , 28222, Spain
Marbella , 29603, Spain
Swansea Carmarthenshire, SA2 8, United Kingdom
Withington Manchester, M20 4, United Kingdom
Oxford Oxfordshire, OX3 7, United Kingdom
Sutton , SM2 5, United Kingdom
How clear is this clinincal trial information?