Non Hodgkin Lymphoma Clinical Trial

Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Follicular Lymphoma

Summary

Follicular Lymphoma (FL) is the second most common B-cell cancer and the most common type of cancer of lymphocytes. Unfortunately, this disease is incurable with conventional treatment and the disease recurs in almost all patients. This study will assess how safe and effective epcoritamab is in combination with lenalidomide and rituximab (R2) in treating adult participants with relapsed or refractory (R/R) FL. Adverse events and change in disease condition will be assessed.

Epcoritamab is an investigational drug being developed for the treatment of FL. Study doctors put the participants in 1 of 3 groups, called treatment arms. Each group receives a different treatment. Around 642 adult participants with R/R FL will be enrolled in approximately 300 sites across the world.

Participants will receive R2 (375 mg/m^2 intravenous infusion of rituximab up to 5 cycles and oral capsules of 20 mg lenalidomide for up to 12 cycles) alone or in combination with subcutaneous injections of epcoritamab for up to 12 cycles (each cycle is 28 days).

There may be higher treatment burden for participants in this trial compared to their standard of care. Participants will attend regular visits during the study at a hospital or clinic. The effect of the treatment will be checked by medical assessments, blood tests, checking for side effects and completing questionnaires.

View Eligibility Criteria

Eligibility Criteria

Inclusion Criteria:

Eastern Cooperative Oncology Group (ECOG) performance status score 0 to 2.

Participant has:

Fluorodeoxyglucose-positron emission tomography (FDG-PET) scan demonstrating positive lesion compatible with computed tomography (CT) or magnetic resonance image (MRI)-defined anatomical tumor sites AND
>= 1 measurable nodal lesion (long axis >= 1.5 cm and short axis > 1.0 cm) or >= 1 measurable extra-nodal lesion (long axis >= 1.0 cm) on CT scan or MRI.
Histologically confirmed Grade 1 to 3a follicular lymphoma (FL) according to the World Health Organization (WHO) 2016 classification with no evidence of histologic transformation to an aggressive lymphoma at most recent representative tumor biopsy and CD20+ on a representative tumor biopsy based on the pathology report.
Relapsed or refractory (R/R) disease to at least one prior systemic regimen that contained an anti-CD20 monoclonal antibody (mAb) in combination with (an)other anti-lymphoma agent(s).
Eligible to receive R2 per investigator determination.

Exclusion Criteria:

Documented refractoriness to lenalidomide.
Have lenalidomide exposure within 12 months prior to randomization.

Study is for people with:

Non Hodgkin Lymphoma

Phase:

Phase 3

Estimated Enrollment:

642

Study ID:

NCT05409066

Recruitment Status:

Recruiting

Sponsor:

AbbVie

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There are 273 Locations for this study

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University of Arizona Cancer Center - North Campus /ID# 228862
Tucson Arizona, 85719, United States
University of Arkansas for Medical Sciences /ID# 227198
Little Rock Arkansas, 72205, United States
Sutter Health Alta Bates Summit Medical Center /ID# 229428
Berkeley California, 94705, United States
Orange Coast Medical Center /ID# 229634
Fountain Valley California, 92708, United States
Saddleback Memorial Medical Center /ID# 229633
Laguna Hills California, 92653, United States
Long Beach Memorial Medical Ct /ID# 228997
Long Beach California, 90806, United States
University of Southern California /ID# 227195
Los Angeles California, 90033, United States
Kaiser Permanente, Waterpark III Institute for Health Research /ID# 228619
Aurora Colorado, 80014, United States
Boca Raton Regional Hospital /ID# 242769
Boca Raton Florida, 33486, United States More Info
Site Coordinator
Contact
561-955-4800
Baptist MD Anderson Cancer Center - Jacksonville /ID# 227270
Jacksonville Florida, 32207, United States
Emory University /ID# 227299
Atlanta Georgia, 30322, United States
Augusta University Georgia Cancer Center /ID# 227313
Augusta Georgia, 30912, United States
Northwestern University /ID# 227248
Chicago Illinois, 60611, United States
Goshen Center for Cancer Care /ID# 227189
Goshen Indiana, 46526, United States
University of Maryland School of Medicine /ID# 227191
Baltimore Maryland, 21201, United States
Massachusetts General Hospital /ID# 245233
Boston Massachusetts, 02114, United States
UMass Chan Medical School /ID# 227323
Worcester Massachusetts, 01655, United States
Henry Ford Health System /ID# 227250
Detroit Michigan, 48202, United States
Mmcorc /Id# 227177
Saint Louis Park Minnesota, 55416, United States
St. Luke's Hospitals /ID# 247817
Chesterfield Missouri, 63017, United States
Alliance for Multispecialty Research (AMR) - Kansas City /ID# 231075
Kansas City Missouri, 64114, United States
St. Vincent Frontier Cancer Center /ID# 251220
Billings Montana, 59102, United States
Morristown Medical Center /ID# 231427
Morristown New Jersey, 07960, United States
Roswell Park Comprehensive Cancer Center /ID# 239128
Buffalo New York, 14263, United States
NYU Langone - Laura and Isaac Perlmutter Cancer Center /ID# 227322
New York New York, 10016, United States
Icahn School of Medicine at Mount Sinai /ID# 227181
New York New York, 10029, United States
Memorial Sloan Kettering Cancer Center-Koch Center /ID# 227193
New York New York, 10065, United States
University of Rochester Cancer Center /ID# 227870
Rochester New York, 14642, United States
Cape Fear Valley Medical Center /ID# 246915
Fayetteville North Carolina, 28304, United States
East Carolina University Brody School of Medicine /ID# 227192
Greenville North Carolina, 27834, United States
The Christ Hospital /ID# 229335
Cincinnati Ohio, 45219, United States
Fox Chase Cancer Center /ID# 231484
Philadelphia Pennsylvania, 19111, United States
Lankenau Medical Center /ID# 228921
Wynnewood Pennsylvania, 19096, United States
Medical University of South Carolina /ID# 227351
Charleston South Carolina, 29425, United States
Virginia Commonwealth University Medical Center Main Hospital /ID# 227211
Richmond Virginia, 23219, United States
UW, Cancer Ctr ProHealth Care /ID# 228746
Waukesha Wisconsin, 53188, United States
Hospital Universitario Austral /ID# 230865
Pilar Buenos Aires, 1629, Argentina
Hospital Italiano de Buenos Aires /ID# 229699
Ciudad Autonoma Buenos Aires Ciuadad Autonoma De Buenos Aires, 1199, Argentina
Fundaleu /Id# 229700
Ciudad Autonoma de Buenos Aire Ciuadad Autonoma De Buenos Aires, 1114, Argentina
Cemic /Id# 229697
Ciudad Autonoma de Buenos Aire Ciuadad Autonoma De Buenos Aires, 1431, Argentina
Hospital Privado Univesitario /ID# 229701
Cordoba , 5016, Argentina
Clinica de Nefrologia, Urologia y Enfermedades Cardiovasculares /ID# 232124
Santa Fe , 3000, Argentina
Royal Prince Alfred Hospital /ID# 239272
Camperdown New South Wales, 2050, Australia
Nepean Hospital /ID# 239093
Kingswood New South Wales, 2747, Australia
Townsville University Hospital /ID# 231124
Douglas Queensland, 4814, Australia
Fiona Stanley Hospital /ID# 231122
Murdoch Western Australia, 6150, Australia
Royal Perth Hospital /ID# 230456
Perth Western Australia, 6000, Australia
Peninsula Private Hospital /ID# 238796
Langwarrin , 3910, Australia
Universitaetsklinikum St. Poelten /ID# 234015
Sankt Poelten Niederoesterreich, 3100, Austria
Ordensklinikum Linz GmbH Elisabethinen /ID# 247510
Linz Oberoesterreich, 4010, Austria
Landeskrankenhaus Salzburg-Universitätsklinikum der PMU (LKH) /ID# 228366
Salzburg , 5020, Austria
Uza /Id# 228521
Edegem Antwerpen, 2650, Belgium
Universitair Ziekenhuis Leuven /ID# 247780
Leuven Vlaams-Brabant, 3000, Belgium
Pôle Hospitalier Jolimont /ID# 228520
La Louvière , 7100, Belgium
Groupe Sante CHC - Clinique du MontLegia /ID# 230415
Liege , 4000, Belgium
Vitaz /Id# 228525
Sint-Niklaas , 9100, Belgium
AZ Turnhout - Campus Sint-Elisabeth /ID# 231628
Turnhout , 2300, Belgium
Hospital de Clinicas da Universidade Federal do Parana /ID# 228123
Curitiba Parana, 80060, Brazil
Hospital Amaral Carvalho - Fundacao Doutor Amaral Carvalho /ID# 228129
Jaú Sao Paulo, 17210, Brazil
Fundacao Antonio Prudente - AC Camargo Cancer Center /ID# 228130
São Paulo Sao Paulo, 01509, Brazil
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA) /ID# 228706
Rio de Janeiro , 20231, Brazil
Real e Benemérita Associação Portuguesa de Beneficência /ID# 228121
Sao Paulo , 01323, Brazil
Instituto de Assistencia Medica ao Servidor Publico Estadual /ID# 230182
Sao Paulo , 04039, Brazil
Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo /ID# 228127
Sao Paulo , 05403, Brazil
Cross Cancer Institute /ID# 249080
Edmonton Alberta, T6G 1, Canada
BC Cancer - Victoria /ID# 228850
Victoria British Columbia, V8R 6, Canada
Saint John Regional Hospital /ID# 233548
Saint John New Brunswick, E2L 4, Canada
Victoria Hospital /ID# 229409
London Ontario, N6A 4, Canada
CSSS Alphonse-Desjardins, CHAU de Levis /ID# 229896
Levis Quebec, G6V 3, Canada
CHUQ- Hôpital de l'Enfant-Jesus /ID# 231537
Quebec City Quebec, G1J 1, Canada
CISSSBSL -Hopital regional de Rimouski /ID# 229894
Rimouski Quebec, G5L 5, Canada
Peking University First Hospital /ID# 250517
Beijing Beijing, 10003, China
Peking University Third Hospital /ID# 230885
Beijing Beijing, 10019, China
Fujian Medical University Union Hospital /ID# 233919
Fuzhou Fujian, 35000, China
The First Affiliated Hospital of Xiamen University /ID# 238427
Xiamen Fujian, 36100, China
Sun Yat-Sen University Cancer Center /ID# 231463
Guangzhou Guangdong, 51006, China
Guangdong Provincial People's Hospital /ID# 232512
Guangzhou Guangdong, 51008, China
Nanfang Hospital of Southern Medical University /ID# 230383
Guangzhou Guangdong, 51051, China
The Fourth Hospital of Hebei Medical University /ID# 238657
Shijiazhuang Hebei, 05001, China
Henan Cancer Hospital /ID# 230459
Zhengzhou Henan, 45000, China
Hubei Cancer Hospital /ID# 232255
Wuhan Hubei, 43007, China
Hunan Cancer Hospital /ID# 232153
Changsha Hunan, 41000, China
Jiangsu Cancer Hospital /ID# 232470
Nanjing Jiangsu, 21000, China
The First Affiliated Hospital of Soochow University /ID# 232511
Suzhou Jiangsu, 21500, China
The Affiliated Hospital of Xuzhou Medical University /ID# 232513
Xuzhou Jiangsu, 22100, China
The First Affiliated Hospital of Nanchang University /ID# 231047
Nanchang Jiangxi, 33000, China
The First Hospital of China Medical University /ID# 232509
Shenyang Liaoning, 11000, China
Xijing Hospital /ID# 238650
Xi'an Shaanxi, 71003, China
Fudan University Shanghai Cancer Center /Id# 250475
Shanghai Shanghai, 20003, China
Yunnan Cancer Hospital /ID# 232062
Kunming Yunnan, 65011, China
The First Affiliated Hospital, Zhejiang University School of Medicine /ID# 230390
Hangzhou Zhejiang, 31000, China
The second Affiliated hospital of Zhejiang University school of Medicine /ID# 231250
Hangzhou Zhejiang, 31000, China
Zhejiang Cancer hospital /ID# 231389
Hangzhou Zhejiang, 31002, China
Jiangxi Cancer Hospital /ID# 232507
Nanchang , 33002, China
Tianjin Medical University Cancer Institute and Hospital /ID# 230876
Tianjin , 30006, China
Union Hospital affiliated to Tongji Medical College of Huazhong University of Sc /ID# 234153
Wuhan , 42002, China
Fakultni Nemocnice Brno /ID# 228271
Brno , 625 0, Czechia
Fakultni nemocnice Hradec Kralove /ID# 228269
Hradec Kralove , 500 0, Czechia
Fakultni nemocnice Kralovske Vinohrady /ID# 228564
Praha , 100 3, Czechia
Vseobecna fakultni nemocnice v Praze /ID# 228565
Praha , 128 0, Czechia
Fakultni Nemocnice v Motole /ID# 228272
Praha , 150 0, Czechia
Sygehus Lillebælt, Vejle /ID# 227404
Vejle Syddanmark, 7100, Denmark
Regionshospitalet Godstrup /ID# 227466
Herning , 7400, Denmark
CHU Clermont-Ferrand /ID# 238676
Clermont Auvergne-Rhone-Alpes, 63100, France
HCL - Hopital Lyon Sud /ID# 231449
Pierre Benite CEDEX Auvergne-Rhone-Alpes, 69495, France
CHU de Rennes - PONTCHAILLOU /ID# 230356
Rennes Bretagne, 35000, France
CHU Dijon /ID# 230354
Dijon Cote-d Or, 21000, France
CHU Limoges - Dupuytren 1 /ID# 231450
Limoges CEDEX 1 Franche-Comte, 87042, France
CHU NIMES - Hopital Caremeau /ID# 230351
Nimes CEDEX 9 Gard, 30029, France
CHU Bordeaux - Hopital Haut Leveque /ID# 230347
Pessac Gironde, 33604, France
CHRU Lille - Hopital Claude Huriez /ID# 230353
Lille Hauts-de-France, 59037, France
CHU Reims - Hôpital Robert Debre /ID# 248710
Reims CEDEX Marne, 51092, France
CHRU Nancy - Hopitaux de Brabois /ID# 241595
Vandoeuvre-les-Nancy Meurthe-et-Moselle, 54500, France
CHU de Nantes, Hotel Dieu -HME /ID# 245928
Nantes Pays-de-la-Loire, 44000, France
CHU Poitiers - La milétrie /ID# 230357
Poitiers Poitou-Charentes, 86000, France
Centre Leon Berard /ID# 230348
Lyon CEDEX 08 Rhone, 69373, France
CHU de CAEN - Hopital de la Cote de Nacre /ID# 245929
Caen , 14033, France
Hopital Henri Mondor /ID# 230358
Creteil , 94000, France
CHD Vendée- La Roche-sur-Yon - Les Oudairies /ID# 234095
La Roche Sur Yon , 85000, France
AP-HP - Hopital Saint-Louis /ID# 232067
Paris , 75010, France
Hopital Pitie Salpetriere /ID# 230360
Paris , 75013, France
IUCT Oncopole /ID# 233486
Toulouse Cedex 9 , 31059, France
Universitaetsklinikum Tuebingen /ID# 229663
Tubingen Baden-Wuerttemberg, 72076, Germany
Universitaetsklinikum Giessen /ID# 234245
Gießen Hessen, 35392, Germany
Universitaetsklinikum Leipzig /ID# 242907
Leipzig Sachsen, 04103, Germany
Universitaetsklinikum Jena /ID# 232064
Jena Thueringen, 07747, Germany
Sozialstiftung Bamberg /ID# 229184
Bamberg , 96049, Germany
Helios Klinikum Berlin-Buch /ID# 229178
Berlin , 13125, Germany
Universitaetsklinikum Carl Gustav Carus an der TU Dresden /ID# 229754
Dresden , 01307, Germany
Universitaetsklinikum Essen /ID# 229180
Essen , 45147, Germany
SRH Wald-Klinikum Gera /ID# 232117
Gera , 07548, Germany
Universitaetsmedizin Goettingen /ID# 230411
Goettingen , 37075, Germany
Klinikum Kassel /ID# 229185
Kassel , 34125, Germany
Otto-von-Guericke-Universitaet /ID# 230144
Magdeburg , 39120, Germany
Klinikum Mutterhaus der Borromäerinnen /ID# 232354
Trier , 54290, Germany
Universitaetsklinikum Wuerzburg /ID# 229278
Wuerzburg , 97080, Germany
General Hospital of Athens Laiko /ID# 226626
Athens Attiki, 11527, Greece
Alexandra General Hospital /ID# 226632
Athens Attiki, 11528, Greece
University General Hospital Attikon /ID# 226629
Athens Attiki, 12462, Greece
General Hospital of Athens Evaggelismos and Ophthalmiatrio of Athens Polyclinic /ID# 226633
Athens , 10676, Greece
University General Hospital of Ioannina /ID# 226628
Ioannina , 45500, Greece
General University Hospital of Thessaloniki AXEPA /ID# 226630
Thessaloniki , 54636, Greece
Theageneio Anticancer Hospital /ID# 226627
Thessaloniki , 54639, Greece
Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont /ID# 229289
Szeged Csongrad, 6725, Hungary
Debreceni Egyetem Klinikai Kozpont /ID# 229287
Debrecen Hajdu-Bihar, 4032, Hungary
Somogy Megyei Kaposi Mor Oktato Korhaz /ID# 246475
Kaposvár Somogy, 7400, Hungary
Szabolcs-Szatmar-Bereg Megyei Korhazak es Egyetemi Oktatokorhaz Josa Andras Okta /ID# 232203
Nyiregyhaza Szabolcs-Szatmar-Bereg, 4400, Hungary
Markusovszky Egyetemi Oktatokorhaz /ID# 229290
Szombathely Vas, 9700, Hungary
Semmelweis Egyetem /ID# 229291
Budapest , 1085, Hungary
Del-pesti Centrumkorhaz Orszagos Hematologiai es Infektologiai Intezet /ID# 229286
Budapest , 1097, Hungary
Orszagos Onkologiai Intezet /ID# 229292
Budapest , 1122, Hungary
The Chaim Sheba Medical Center /ID# 228322
Ramat Gan Tel-Aviv, 52656, Israel
Tel Aviv Sourasky Medical Center /ID# 228529
Tel Aviv-Yafo Tel-Aviv, 64239, Israel
Assaf Harofeh Medical Center /ID# 228037
Be'Er Ya'Akov , 70300, Israel
Rambam Health Care Campus /ID# 227849
Haifa , 31096, Israel
Hadassah /ID# 227846
Jerusalem , 91120, Israel
Rabin Medical Center /ID# 228043
Petakh Tikva , 49414, Israel
Ziv Medical Center /ID# 232257
Safed , 13100, Israel
Fondazione di Religione e di Culto Casa Sollievo della Sofferenza /ID# 228458
San Giovanni Rotondo Foggia, 71013, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS-Università Cattolica /ID# 230402
Rome Lazio, 00168, Italy
Ospedale San Raffaele IRCCS /ID# 228669
Milan Milano, 20132, Italy
IEO -Istituto Europeo di Oncologia /ID# 227396
Milan Milano, 20141, Italy
Azienda Ospedaliera Universitaria Citta della Salute e della Scienza di Torino /ID# 229820
Torino Piemonte, 10126, Italy
Istituto di Candiolo Fondazione del Piemonte per l'Oncologia IRCCS /ID# 229602
Candiolo Torino, 10060, Italy
Azienda Ospedaliera Nazionale SS. Antonio e Biagio e Cesare Arrigo /ID# 227401
Alessandria , 15121, Italy
Centro di Riferimento Oncologico /ID# 227395
Aviano , 33081, Italy
I.R.C.C.S Istituto Tumori Giovanni Paolo II /ID# 227400
Bari , 70124, Italy
ASST Spedali civili di Brescia /ID# 227397
Brescia , 25123, Italy
Azienda Ospedaliera Universitaria Federico II /ID# 230403
Napoli , 80131, Italy
Azienda Ospedaliero Universitaria Maggiore della Carita di Novara /ID# 227399
Novara , 28100, Italy
A.O. Ospedali Riuniti Villa Sofia - Cervello /ID# 227402
Palermo , 90146, Italy
Ospedale Santa Maria Croci /ID# 227394
Ravenna , 48121, Italy
NHO Nagoya Medical Center /ID# 230678
Nagoya-shi Aichi, 460-0, Japan
Aichi Cancer Center Hospital /ID# 230134
Nagoya-shi Aichi, 464-8, Japan
National Cancer Center Hospital East /ID# 232423
Kashiwa-shi Chiba, 277-8, Japan
Matsuyama Red Cross Hospital /ID# 251866
Matsuyama-shi Ehime, 790-8, Japan
Kyushu University Hospital /ID# 230136
Fukuoka-shi Fukuoka, 812-8, Japan
Fukushima Medical University Hospital /ID# 251839
Fukushima-shi Fukushima, 960-1, Japan
Hokkaido University Hospital /ID# 231443
Sapporo-shi Hokkaido, 060-8, Japan
Kobe City Medical Center General Hospital /ID# 251945
Kobe-shi Hyogo, 650-0, Japan
Kagoshima University Hospital /ID# 232251
Kagoshima-shi Kagoshima, 890-8, Japan
Kyoto University Hospital /ID# 231156
Kyoto-shi Kyoto, 606-8, Japan
Tohoku University Hospital /ID# 232303
Sendai-shi Miyagi, 98085, Japan
Okayama University Hospital /ID# 232009
Okayama-shi Okayama, 700-8, Japan
Kindai University Hospital /ID# 232152
Osakasayama-shi Osaka, 589-8, Japan
National Cancer Center Hospital /ID# 230004
Chuo-ku Tokyo, 104-0, Japan
Yamagata University Hospital /ID# 230005
Yamagata-shi Yamagata, 990-9, Japan
Seoul National University Bundang Hospital /ID# 228448
Seongnam Gyeonggido, 13620, Korea, Republic of
Inje University Busan Paik Hospital /ID# 230293
Busan , 47392, Korea, Republic of
Dong-A University Hospital /ID# 228638
Busan , 49201, Korea, Republic of
Pusan National University Hospital /ID# 229798
Busan , 49241, Korea, Republic of
Keimyung University Dongsan Medical Center /ID# 229800
Daegu , 41931, Korea, Republic of
Jeonbuk National University Hospital /ID# 228908
Jeonju , 54907, Korea, Republic of
Seoul National University Hospital /ID# 228446
Seoul , 03080, Korea, Republic of
Asan Medical Center /ID# 228444
Seoul , 05505, Korea, Republic of
Samsung Medical Center /ID# 228445
Seoul , 06351, Korea, Republic of
The Catholic University of Korea, Seoul St. Mary's Hospital /ID# 228447
Seoul , 06591, Korea, Republic of
Dijklander Ziekenhuis /ID# 248993
Hoorn Nh Noord-Holland, 1624 , Netherlands
Albert Schweitzer Ziekenhuis /ID# 247740
Dordrecht Zuid-Holland, 3318 , Netherlands
Onze Lieve Vrouwe Gasthuis /ID# 247899
Amsterdam , 1091 , Netherlands
Amphia Ziekenhuis /ID# 247739
Breda , 4818 , Netherlands
Deventer Ziekenhuis /ID# 247853
Deventer , 7416 , Netherlands
Medisch Spectrum Twente /ID# 247854
Enschede , 7512 , Netherlands
Admiraal de Ruyter Ziekenhuis /ID# 247692
Goes , 4462 , Netherlands
Universitair Medisch Centrum Groningen /ID# 247741
Groningen , 9713 , Netherlands
Leids Universitair Medisch Centrum /ID# 247742
Leiden , 2333 , Netherlands
St. Antonius Ziekenhuis /ID# 248644
Nieuwegein , 3435 , Netherlands
Canisius-Wilhelmina Ziekenhuis /ID# 248138
Nijmegen , 2025, New Zealand
North Shore Hospital /ID# 228508
Takapuna Auckland, 0622, New Zealand
Palmerston North Hospital /ID# 232352
Palmerston North Manawatu-Wanganui, 4442, New Zealand
Pratia MCM Krakow /ID# 229121
Krakow Malopolskie, 30-51, Poland
Szpitale Pomorskie Sp. z o.o /ID# 229122
Gdynia Pomorskie, 81-51, Poland
Swietokrzyskie Centrum Onkologii Samodzielny Publiczny Zaklad Opieki Zdrowotnej /ID# 229362
Kielce Swietokrzyskie, 25-73, Poland
ARS-MEDICAL Sp. z o.o. /ID# 229601
Pila Wielkopolskie, 64-92, Poland
Centrum Medyczne Pratia Poznan /ID# 229299
Skorzewo Wielkopolskie, 60-18, Poland
Hematology and Oncology Institute /ID# 230056
Manati , 00674, Puerto Rico
Pan American Center for Oncology Trials, LLC /ID# 230055
Rio Piedras , 00935, Puerto Rico
Auxilio Mutuo Cancer Center /ID# 248721
San Juan , 00918, Puerto Rico
Narodny Onkologicky ustav /ID# 239510
Bratislava , 831 0, Slovakia
Univerzitna nemocnica L. Pasteura Kosice /ID# 240175
Kosice , 040 0, Slovakia
Univerzitna nemocnica Martin /ID# 240827
Martin , 036 0, Slovakia
Wits Clinical Research Site /ID# 228895
Johannesburg Gauteng, 2193, South Africa
Albert Alberts Stem Cell Transplant Centre /ID# 228896
Pretoria Gauteng, 0044, South Africa
University of Cape Town /ID# 228900
Cape Town Western Cape, 7925, South Africa
Haemalife Inc. Netcare Kuilsrivier Hospital /ID# 243392
Kuilsrivier Western Cape, 7580, South Africa
Instituto Catalan de Oncologia (ICO) Badalona /ID# 228108
Badalona Barcelona, 08916, Spain
Instituto Catalan de Oncologia (ICO) L'Hospitalet /ID# 228107
Hospitalet de Llobregat Barcelona, 08908, Spain
Hospital Unversitario Marques de Valdecilla /ID# 228984
Santander Cantabria, 39008, Spain
CLINICA UNIVERSIDAD DE NAVARRA-Pamplona /ID# 228116
Pamplona Navarra, 31008, Spain
Hospital Parc de Salut del Mar /ID# 228106
Barcelona , 08003, Spain
Hospital Santa Creu i Sant Pau /ID# 229859
Barcelona , 08041, Spain
Hospital San Pedro de Alcantara /ID# 248845
Caceres , 10003, Spain
Hospital Universitario Reina Sofia /ID# 228122
Cordoba , 14004, Spain
CLINICA UNIVERSIDAD DE NAVARRA-Madrid /ID# 229157
Madrid , 28027, Spain
MD Anderson Madrid /ID# 229860
Madrid , 28033, Spain
Hospital Universitario Ramon y Cajal /ID# 228113
Madrid , 28034, Spain
Hospital Universitario Fundacion Jimenez Diaz /ID# 228110
Madrid , 28040, Spain
Hospital Universitario 12 de Octubre /ID# 228109
Madrid , 28041, Spain
Hospital Universitario de Salamanca /ID# 228117
Salamanca , 37711, Spain
Hospital Universitario Virgen del Rocio /ID# 228118
Sevilla , 41013, Spain
Sunderby sjukhus /ID# 228165
Lulea Norrbottens Lan, 971 8, Sweden
Sodra Alvsborgs sjukhus /ID# 228886
Boras Vastra Gotalands Lan, 501 8, Sweden
Linkoping University Hospital /ID# 233520
Linkoping , 581 8, Sweden
Kantonsspital Aarau AG /ID# 229113
Aarau Aargau, 5001, Switzerland
Kantonsspital St. Gallen /ID# 229117
St. Gallen Sankt Gallen, 9007, Switzerland
EOC Ospedale Regionale di Bellinzona e Valli /ID# 228922
Bellinzona Ticino, 6500, Switzerland
Universitatsspital Zurich /ID# 228920
Zurich Zuerich, 8091, Switzerland
Kaohsiung Chang Gung Memorial Hospital /ID# 227384
Kaohsiung , 833, Taiwan
China Medical University Hospital /ID# 227379
Taichung City , 40447, Taiwan
Taichung Veterans General Hospital /ID# 227383
Taichung , 40705, Taiwan
National Cheng Kung University Hospital /ID# 227381
Tainan , 704, Taiwan
Taipei Veterans General Hosp /ID# 227380
Taipei City , 11217, Taiwan
Ankara Universitesi Fakultesi /ID# 227790
Ankara , 06620, Turkey
Akdeniz Universitesi Tip Fakul /ID# 227791
Antalya , 07059, Turkey
Dicle Universitesi Tip /ID# 230087
Diyarbakir , 21200, Turkey
Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty /ID# 248202
Istanbul , 34098, Turkey
Istanbul Florence Nightingale Hastanesi /ID# 229546
Istanbul , 34200, Turkey
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi /ID# 227855
Istanbul , 34899, Turkey
Ege University Medical Faculty /ID# 227792
Izmir , 35040, Turkey
Kocaeli University Med Faculty /ID# 227854
Kocaeli , 41380, Turkey
Ondokuz mayis University Facul /ID# 227794
Samsun , 55200, Turkey
University Hospital of Derby and Burton NHS Foundation Trust /ID# 234093
Derby Derbyshire, DE22 , United Kingdom
Barts Health NHS Trust /ID# 230028
London London, City Of, E1 2E, United Kingdom
Oxford University Hospitals NHS Foundation Trust /ID# 230035
Oxford Oxfordshire, OX3 9, United Kingdom
NHS Greater Glasgow and Clyde /ID# 230027
Glasgow Scotland, G12 0, United Kingdom
University Hospitals of North Midlands NHS Trust /ID# 230042
Stoke-on-Trent Staffordshire, ST4 6, United Kingdom
University Hospitals Birmingham NHS Foundation Trust /ID# 230043
Birmingham , B15 2, United Kingdom
East Kent Hospitals University NHS Foundation Trust /ID# 230152
Canterbury , CT1 3, United Kingdom
East Suffolk and North Essex NHS Foundation Trust /ID# 230040
Colchester , CO4 5, United Kingdom
Leeds Teaching Hospitals NHS Trust /ID# 230471
Leeds , LS9 7, United Kingdom
The Clatterbridge Cancer Centre NHS Foundation Trust /ID# 230036
Liverpool , L7 8Y, United Kingdom
University College London Hospitals NHS Foundation Trust /ID# 249468
London , NW1 2, United Kingdom
The Christie Hospital /ID# 230124
Manchester , M20 4, United Kingdom
The Newcastle Upon Tyne Hospitals NHS Foundation Trust /ID# 230123
Newcastle upon Tyne , NE7 7, United Kingdom
University Hospital Plymouth NHS Trust /ID# 230038
Plymouth , PL6 5, United Kingdom
Portsmouth Hospitals University NHS Trust /ID# 230044
Portsmouth , PO6 3, United Kingdom
South Tyneside and Sunderland NHS Foundation Trust /ID# 230039
South Shields , NE34 , United Kingdom

How clear is this clinincal trial information?

Study is for people with:

Non Hodgkin Lymphoma

Phase:

Phase 3

Estimated Enrollment:

642

Study ID:

NCT05409066

Recruitment Status:

Recruiting

Sponsor:


AbbVie

How clear is this clinincal trial information?

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